DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6985 and RDH54

DIOPT Version :9

Sequence 1:	NP_651091.1	Gene:	CG6985 / 42694	FlyBaseID:	FBgn0039017	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_009629.6	Gene:	RDH54 / 852365	SGDID:	S000000277	Length:	958	Species:	Saccharomyces cerevisiae

Alignment Length:	507	Identity:	99/507 - (19%)
Similarity:	179/507 - (35%)	Gaps:	188/507 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 TSGGTQSLG--PREFRAGENPLKDSRIFHVLWRNQTTKKHKTWTGNG--TLVVTGSIVTLKDDTG 95
            ::|.|.:|.  |....:.||    :|.|.:::|..||||||||:|:|  ||..:...:...::.|
Yeast    85 SAGPTLNLAKKPNNLSSNEN----TRYFTIMYRKPTTKKHKTWSGDGYATLKASSDKLCFYNEAG 145

  Fly    96 KVV---------DTM--TYFKQRQLQENDQLEVGSKDVEIQEEIKTVEECLIQRQLEIANWCQKI 149
            |.:         |::  |.||           .||.:|::..|:|        ...||.:..:.:
Yeast   146 KFLGSSMLPSDSDSLFETLFK-----------AGSNEVQLDYELK--------ENAEIRSAKEAL 191

  Fly   150 DAQNGCTDTSPPPADSAPVRSHLLKKIKREADAFAPPHLEISQHREDKHVSYAAADSSTSMGKKI 214
            ....|  :.|||...:    :..:...|.:...:..|   :||                     :
Yeast   192 SQNMG--NPSPPTTST----TETVPSTKNDGGKYQMP---LSQ---------------------L 226

  Fly   215 YEQNTLK-IENPTKEFTQSEYLCLLTPAELQKKILLFVSEYAQTSKTESSTLKEIFQI-VCDHPV 277
            :..||:| .::.||:..:.               :..|.:.:|.||.:.  ...:|.: ..|:|:
Yeast   227 FSLNTVKRFKSVTKQTNEH---------------MTTVPKTSQNSKAKK--YYPVFDVNKIDNPI 274

  Fly   278 LLKTLGTNPVFKEIMEVLDAILPPWPSMGLY------DSAKFEFLHVM------LDHLVAERGEK 330
            ::.        |.....:|.|:.  |.:|.:      :..||.:..:|      :::...:...|
Yeast   275 VMN--------KNAAAEVDVIVD--PLLGKFLRPHQREGVKFMYDCLMGLARPTIENPDIDCTTK 329

  Fly   331 CCILANSED---CL------------------TLVRGYCQSYSLDHAQLDGPQKVNLFNSLADGE 374
            ..:|.|..|   ||                  ||:|           |.....||:...|   |.
Yeast   330 SLVLENDSDISGCLLADDMGLGKTLMSITLIWTLIR-----------QTPFASKVSCSQS---GI 380

  Fly   375 PMIGL------------------------------ILTSDLSALRALRCKHLIIYNHNSRQQANQ 409
            |:.||                              :||  ||:..:.....:.:.|....|:..|
Yeast   381 PLTGLCKKILVVCPVTLIGNWKREFGKWLNLSRIGVLT--LSSRNSPDMDKMAVRNFLKVQRTYQ 443

  Fly   410 LLAVGAMDTKIYTLITAGGSPEELQFYGHMGD----DSIEDLQNCRSQLIPT 457
            :|.:|.  .|:.::      .|||:...|:.|    |....|:|..|:::.|
Yeast   444 VLIIGY--EKLLSV------SEELEKNKHLIDMLVCDEGHRLKNGASKILNT 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6985	NP_651091.1	DUF2439	60..128	CDD:287368	23/80 (29%)
RDH54	NP_009629.6	DUF2439	108..>158	CDD:402138	16/49 (33%)
		DEXHc_RAD54	296..573	CDD:350762	40/216 (19%)
		SF2_C_SNF	663..789	CDD:350180
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0390
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900