Protein Alignment CG6985 and RDH54

DIOPT Version :10

• Sequence 1: NP_651091.1
• Gene: CG6985 / 42694
• FlyBaseID: FBgn0039017
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_009629.6
• Gene: RDH54 / 852365
• SGDID: S000000277
• Length: 958
• Species: Saccharomyces cerevisiae
• Alignment Length: 507
• Identity: 99/507 - (19%)
• Similarity: 179/507 - (35%)
• Gaps: 188/507 - (37%)

  Fly    35 TSGGTQSLG--PREFRAGENPLKDSRIFHVLWRNQTTKKHKTWTGNG--TLVVTGSIVTLKDDTG 95
            ::|.|.:|.  |....:.||    :|.|.:::|..||||||||:|:|  ||..:...:...::.|
Yeast    85 SAGPTLNLAKKPNNLSSNEN----TRYFTIMYRKPTTKKHKTWSGDGYATLKASSDKLCFYNEAG 145

  Fly    96 KVV---------DTM--TYFKQRQLQENDQLEVGSKDVEIQEEIKTVEECLIQRQLEIANWCQKI 149
            |.:         |::  |.||           .||.:|::..|:|        ...||.:..:.:
Yeast   146 KFLGSSMLPSDSDSLFETLFK-----------AGSNEVQLDYELK--------ENAEIRSAKEAL 191

  Fly   150 DAQNGCTDTSPPPADSAPVRSHLLKKIKREADAFAPPHLEISQHREDKHVSYAAADSSTSMGKKI 214
            ....|  :.|||...:    :..:...|.:...:..|   :||                     :
Yeast   192 SQNMG--NPSPPTTST----TETVPSTKNDGGKYQMP---LSQ---------------------L 226

  Fly   215 YEQNTLK-IENPTKEFTQSEYLCLLTPAELQKKILLFVSEYAQTSKTESSTLKEIFQI-VCDHPV 277
            :..||:| .::.||:..:.               :..|.:.:|.||.:.  ...:|.: ..|:|:
Yeast   227 FSLNTVKRFKSVTKQTNEH---------------MTTVPKTSQNSKAKK--YYPVFDVNKIDNPI 274

  Fly   278 LLKTLGTNPVFKEIMEVLDAILPPWPSMGLY------DSAKFEFLHVM------LDHLVAERGEK 330
            ::.        |.....:|.|:.  |.:|.:      :..||.:..:|      :::...:...|
Yeast   275 VMN--------KNAAAEVDVIVD--PLLGKFLRPHQREGVKFMYDCLMGLARPTIENPDIDCTTK 329

  Fly   331 CCILANSED---CL------------------TLVRGYCQSYSLDHAQLDGPQKVNLFNSLADGE 374
            ..:|.|..|   ||                  ||:|           |.....||:...|   |.
Yeast   330 SLVLENDSDISGCLLADDMGLGKTLMSITLIWTLIR-----------QTPFASKVSCSQS---GI 380

  Fly   375 PMIGL------------------------------ILTSDLSALRALRCKHLIIYNHNSRQQANQ 409
            |:.||                              :||  ||:..:.....:.:.|....|:..|
Yeast   381 PLTGLCKKILVVCPVTLIGNWKREFGKWLNLSRIGVLT--LSSRNSPDMDKMAVRNFLKVQRTYQ 443

  Fly   410 LLAVGAMDTKIYTLITAGGSPEELQFYGHMGD----DSIEDLQNCRSQLIPT 457
            :|.:|.  .|:.::      .|||:...|:.|    |....|:|..|:::.|
Yeast   444 VLIIGY--EKLLSV------SEELEKNKHLIDMLVCDEGHRLKNGASKILNT 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6985	NP_651091.1	DUF2439	60..128	CDD:463065	23/80 (29%)
RDH54	NP_009629.6	DUF2439	108..>158	CDD:463065	16/49 (33%)
		DEXHc_RAD54	296..573	CDD:350762	40/216 (19%)
		SF2_C_SNF	663..789	CDD:350180