Protein Alignment CG6985 and Rad54b

DIOPT Version :10

• Sequence 1: NP_651091.1
• Gene: CG6985 / 42694
• FlyBaseID: FBgn0039017
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001034645.1
• Gene: Rad54b / 623474
• MGIID: 3605986
• Length: 886
• Species: Mus musculus
• Alignment Length: 758
• Identity: 136/758 - (17%)
• Similarity: 208/758 - (27%)
• Gaps: 356/758 - (46%)

  Fly    20 SPCSWPKNNLPSEWGTSGGTQSLGP--------REFRAGENPLKD-SRIFHVLWRNQTTKKHKTW 75
            :||  |...:|.|.|.......|.|        .|.:|.|..... .:.|.|:|...:.||||.|
Mouse    60 NPC--PSEGIPREVGDGTRVDPLPPVHSASKEITESKAQEEEASSLLKYFSVVWCKASKKKHKKW 122

  Fly    76 TGNGTLVVTGSIVTLKDDTGKVVDTMTYFKQRQL---QENDQLEVGSKDVEIQEEI--------- 128
            .|:..|:|.|...||||..||.:.....:|.:.|   :|...|.:|.|::||...|
Mouse   123 EGDAILIVRGRSFTLKDLEGKDIGRGIGYKFKDLENVEEGQTLIIGGKEIEILGTISSDDFNSGK 187

  Fly   129 --------------KTVEECLIQRQLEIANWCQKIDAQ----NGCTDTSPPPADSA-----PVRS 170
                          :...:|...   ...:.||...||    |.|.....|...:|     |..:
Mouse   188 CFQHGSGSPAVPSSQAARKCFSN---PFKSVCQSTQAQGKRWNDCRPRHNPCTPNALVMPRPDEN 249

  Fly   171 HLLKKIKRE----ADAFAPPHL--EISQHRED------------KHVSYAAADSSTSMG------ 211
            | .:...|.    .|....|||  .:..|::|            :.|....|..:..||
Mouse   250 H-QRMFNRHCSPIVDVVIDPHLVHHLRPHQKDGIIFLYECVMGMRAVGKCGAILADEMGLGKTLQ 313

  Fly   212 -----------------------------------KKIYEQ----NTLKI-----ENPTKEFTQS 232
                                               :|.:::    ..:||     ::..:||..|
Mouse   314 CISLIWTLQCQGPYGGKPVIKKTLIVTPGSLVNNWRKEFQKWLGSERIKIFTVDQDHKVEEFINS 378

  Fly   233 --------EYLCLLTPAELQKKI---LLFVSEYAQTSKTESSTLKEIFQIVCDHPVLLKTLGT-- 284
                    .|..||...:..|.|   ||...|..:...:...|...:..:.|:..|:|  .||
Mouse   379 TFHSVLIISYEMLLRSLDQIKTIPFGLLICDEGHRLKNSSIKTTTALSSLSCEKTVIL--TGTPV 441

  Fly   285 --------------NP-----------------------------------------------VF 288
                          ||                                               :.
Mouse   442 QNDLQEFFALVDFVNPGILGSLSSYRKIYEEPIIISREPSSSKEERELGERRATELTRLTGRFIL 506

  Fly   289 KEIMEVLDAILPP--------WP---SMGLY------DSAKFEFLHVMLD---HLVA-------- 325
            :...||::..|||        .|   .:.||      .|.:| .|..:|:   ||:.
Mouse   507 RRTQEVINKYLPPKIENVVFCRPGALQIELYRKLLRSQSVRF-CLQGLLENSAHLICIGALKKLC 570

  Fly   326 -----------------------------------------------ERG--------------- 328
                                                           |.|
Mouse   571 NHPCLLFSSVKGKEFSSSCEENEERNLCQGLLSVFPAGYNPLQFSEEESGKLQVLVKLLAVIHEL 635

  Fly   329 ---EKCCILANSEDCLTLVRGYCQSYSLDHAQLDGPQKVN-------------------LFNSLA 371
               ||..:::|....|.::...|:.:....|:|||...|:                   |.:|.|
Mouse   636 RPTEKVILVSNYRQTLNVLEEVCKRHGYACARLDGQTPVSQRQHIVDSFNSKYSTDFIFLLSSKA 700

  Fly   372 DGEPMIGLILTSDLSALRALRCKHLIIY----NHNSRQQA---------------NQLLAVGAMD 417
            .|   :||.|...         .|||:|    |..:..||               .:||..|.::
Mouse   701 GG---VGLNLIGG---------SHLILYDIDWNPATDIQAMSRVWRDGQKHPVHIYRLLTTGTIE 753

  Fly   418 TKIY-----------TLITAGGSPEELQFYGHMGDDSIEDLQN 449
            .|||           .::....|.|.:||       |:|:|:|
Mouse   754 EKIYQRQISKQGLSGAVVDLTRSSEHIQF-------SVEELKN 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6985	NP_651091.1	DUF2439	60..128	CDD:463065	26/70 (37%)
Rad54b	NP_001034645.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..95		9/36 (25%)
		HepA	<274..772	CDD:440319	74/512 (14%)
		DEXHc_RAD54B	274..508	CDD:350824	28/235 (12%)
		DEGH box	409..412		1/2 (50%)