| Sequence 1: | NP_524453.1 | Gene: | Dcr-1 / 42693 | FlyBaseID: | FBgn0039016 | Length: | 2249 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_071451.2 | Gene: | IFIH1 / 64135 | HGNCID: | 18873 | Length: | 1025 | Species: | Homo sapiens |
| Alignment Length: | 657 | Identity: | 136/657 - (20%) |
|---|---|---|---|
| Similarity: | 226/657 - (34%) | Gaps: | 186/657 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 18 RDFQVELLATAYE-RNTIICLGHRSSKEFIALKLLQ---ELSRRARRHGRVSVYLSCEVGTSTEP 78
Fly 79 CSIYTMLTHLTDLRVWQEQPDMQIPFDHCW-------TDYHVSILRP----------------EG 120
Fly 121 FLYLLETRE---LLLSSVELIVLEDCHDS---AVYQRI------RPLFENHIMP--APPADRPRI 171
Fly 172 LGLAGPLHSAGCELQQLSAMLATLEQSVLCQIETASDIVTVLRYCSRPHEYIVQCAPFEMDEL-- 234
Fly 235 -------SLVLADVLNTHKSFLLDHRYDPY-----EIYGTDQFMDELKDIPDPKVDPLNVINSLL 287
Fly 288 VVLHEMGPWCTQRAAHHFYQCNEKLKVKTPHERHYLLYCLVSTALIQLYSLCEHAFHRHLGSGSD 352
Fly 353 SRQTIERYSSPKVRRLLQTLRCFKPEEVHTQADGLRRMRHQVDQADFNRLSHTLESKCRMVDQMD 417
Fly 418 QP--PTETRALVATLEQILHTTEDRQTNRSAARVTPTPTPAHAKPKPSSGANTAQPRTRRRVYTR 480
Fly 481 RHHRDHNDGSDTLCALIYCNQNHTARVLFELLAEISRRDPDLKFLRCQYTTDRVADPTTEPKEAE 545
Fly 546 LEHRRQEEVLKRFRMHDCNVLIGTSVLEEGIDVPKCNLVVRWDPPTTYRSYVQCKGRARAAPAYH 610
Fly 611 VILVAPS 617 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Dcr-1 | NP_524453.1 | DEAD-like_helicase_N | 15..208 | CDD:421690 | 52/230 (23%) |
| Dicer_PBD | 240..344 | CDD:277191 | 18/108 (17%) | ||
| DEAD-like_helicase_C | 490..614 | CDD:365791 | 33/123 (27%) | ||
| Dicer_dimer | 825..916 | CDD:397444 | |||
| PAZ_dicer_like | 1091..1212 | CDD:239209 | |||
| RIBOc | 1724..1930 | CDD:238333 | |||
| RIBOc | 2008..2172 | CDD:238333 | |||
| DSRM_DICER | 2177..2240 | CDD:380680 | |||
| IFIH1 | NP_071451.2 | CARD_MDA5_r1 | 8..99 | CDD:260077 | |
| CARD_MDA5_r2 | 111..201 | CDD:260078 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 271..307 | ||||
| ResIII | 305..491 | CDD:282678 | 48/200 (24%) | ||
| MPH1 | 306..873 | CDD:224036 | 136/657 (21%) | ||
| MDA5_ID | 548..694 | CDD:277189 | 33/206 (16%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 640..662 | 2/25 (8%) | |||
| Helicase_C | 698..823 | CDD:278689 | 34/143 (24%) | ||
| MDA5_C | 900..1015 | CDD:276945 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1337630at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.920 | |||||