| Sequence 1: | NP_524453.1 | Gene: | Dcr-1 / 42693 | FlyBaseID: | FBgn0039016 | Length: | 2249 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055129.2 | Gene: | DDX58 / 23586 | HGNCID: | 19102 | Length: | 925 | Species: | Homo sapiens |
| Alignment Length: | 624 | Identity: | 122/624 - (19%) |
|---|---|---|---|
| Similarity: | 233/624 - (37%) | Gaps: | 149/624 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 7 DNNLHTTVFTPRDFQVELLATAYE-RNTIICLGHRSSKEFIALKLLQELSRR--ARRHGRVSVYL 68
Fly 69 SCEVGTSTEPCSIYTMLTHLTDLRVW--QEQPDMQIPFDHCWTDYHVSILRPEGFLYLLETREL- 130
Fly 131 LLSSVELIVLEDCHDSAVYQRIRPLFENHI---MPAPPADRPRILGL-----AGPLHSAGCELQQ 187
Fly 188 LSAMLATLEQSVLCQIETASDIVTVLRYCSRPHEYIVQCAPFEMDELSLVLADVLNTHKSFLLDH 252
Fly 253 RYDPYEIYGTDQFMDELKDIPDPKVDPLNVINSLLVVLHEMGPW-CTQRAAHHFYQCNEK----- 311
Fly 312 ----LKVKTPHERHYLLYCLVSTALIQLYSLCEHAFHRHLGSGSDSRQTIERYSSPKVRRLLQTL 372
Fly 373 RCFKPEEVHTQADGLRRMRHQVDQADFNRLSHTLESKCRMVDQMDQPPTETRALVATLEQILHTT 437
Fly 438 EDRQTNRSAARVTPTPTPAHAKPKPSSGANTAQPRTRRRVYTRRHHRDHNDGSDTLCALIYCNQN 502
Fly 503 HTARVLFELLAEISRRDPDLKFLRCQYTTDRVADPTTEPKEAELEHRRQEEVLKRFRMH-DCNVL 566
Fly 567 IGTSVLEEGIDVPKCNLVVRWDPPTTYRSYVQCKGRARA 605 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Dcr-1 | NP_524453.1 | DEAD-like_helicase_N | 15..208 | CDD:421690 | 41/206 (20%) |
| Dicer_PBD | 240..344 | CDD:277191 | 23/113 (20%) | ||
| DEAD-like_helicase_C | 490..614 | CDD:365791 | 34/117 (29%) | ||
| Dicer_dimer | 825..916 | CDD:397444 | |||
| PAZ_dicer_like | 1091..1212 | CDD:239209 | |||
| RIBOc | 1724..1930 | CDD:238333 | |||
| RIBOc | 2008..2172 | CDD:238333 | |||
| DSRM_DICER | 2177..2240 | CDD:380680 | |||
| DDX58 | NP_055129.2 | DD | 2..92 | CDD:326335 | |
| CARD_RIG-I_r2 | 100..189 | CDD:260076 | |||
| Interaction with ZC3HAV1. /evidence=ECO:0000269|PubMed:21102435 | 218..925 | 122/624 (20%) | |||
| helicase_insert_domain | 243..771 | CDD:327377 | 118/614 (19%) | ||
| DECH box | 372..375 | 0/2 (0%) | |||
| Mediates interaction with RNF135. /evidence=ECO:0000269|PubMed:23950712 | 735..925 | ||||
| RIG-I_C | 805..918 | CDD:276943 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1337630at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.920 | |||||