DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Takl2 and map3k9

DIOPT Version :9

Sequence 1:	NP_651090.2	Gene:	Takl2 / 42692	FlyBaseID:	FBgn0039015	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	XP_689128.2	Gene:	map3k9 / 560639	ZFINID:	ZDB-GENE-081113-5	Length:	1009	Species:	Danio rerio

Alignment Length:	291	Identity:	88/291 - (30%)
Similarity:	141/291 - (48%)	Gaps:	25/291 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VPYEEIQTKELIGTGFYGSVYRAVWRNREIALKRIREGCED------KKIEREIYQLTKASHVNI 66
            :.:.|:..:|:||.|.:|.||||:|..:|:|:|..|...::      :.:.:|.......:|.||
Zfish   131 IDFSELALEEMIGVGGFGKVYRAIWNGQEVAVKAARRDPDEDVSQTLESVRQEAKLFAMLTHPNI 195

  Fly    67 VELYGTSRHEGCALLLMEFVDGGSLSSFLHAKSKPSYSHAHAFNWAHQIAQGIAYLHGMQPKAVI 131
            :.|.|....|....|:||:..||.|:..|..|..|.::   ..:||.|||:.:.|||......||
Zfish   196 MALLGVCLQEPNLCLVMEYARGGPLNRALAGKRIPPHT---LVDWAVQIARAMLYLHCQAIVPVI 257

  Fly   132 HRDIKPLNTLLCEK-------GLKLKICDFGTVVDLSQSISCN-AGTCRYKAPEVLQGNKPDEKC 188
            |||:|..|.|:.|:       ...||:.|||...:..::...: |||..:.||||::.:...:..
Zfish   258 HRDLKSSNILILERVENDDLSNKTLKVTDFGLAREWHRTTKMSAAGTYAWMAPEVIRSSTFSKGS 322

  Fly   189 DVYSWAITFWEILSRKEPFEQYNTLFELY-MAINEGERPDLSCIMSGCPADIVALLYASWDPDIS 252
            ||:|:.:..||:|:.:.||...:.|...| :|:|:...|    |.|.||.....|:...|:.|..
Zfish   323 DVWSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLSLP----IPSTCPEPFARLMEDCWNVDPH 383

  Fly   253 KRFSMELISQSMGRILSEAG--SIPPLDFYS 281
            .|.....|...:..| .|:|  .:|...|.|
Zfish   384 SRPPFTSILDQLTAI-EESGFFEMPAESFQS 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Takl2	NP_651090.2	S_TKc	14..258	CDD:214567	80/258 (31%)
Takl2	NP_651090.2	PKc_like	19..268	CDD:304357	80/263 (30%)
map3k9	XP_689128.2	SH3_MLK1-3	47..104	CDD:212992
		STKc_MLK1	129..398	CDD:271047	82/273 (30%)
		STYKc	136..395	CDD:214568	81/265 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48171
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010