DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Takl2 and Map3k9

DIOPT Version :9

Sequence 1:	NP_651090.2	Gene:	Takl2 / 42692	FlyBaseID:	FBgn0039015	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	XP_038968662.1	Gene:	Map3k9 / 500690	RGDID:	1562149	Length:	1140	Species:	Rattus norvegicus

Alignment Length:	312	Identity:	96/312 - (30%)
Similarity:	143/312 - (45%)	Gaps:	49/312 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VPYEEIQTKELIGTGFYGSVYRAVWRNREIALKRIR--------EGCEDKKIEREIYQLTKASHV 64
            :.:.|:..:|:||.|.:|.||||.|...|:|:|..|        :..|:.:.|.:::.:.|  |.
  Rat   132 IDFAELTLEEIIGIGGFGKVYRAFWVGDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLK--HP 194

  Fly    65 NIVELYGTSRHEGCALLLMEFVDGGSLSSFLHAKSKPSYSHAHAFNWAHQIAQGIAYLHGMQPKA 129
            ||:.|.|....|....|:|||..||.|:..|..|..|.   ....|||.|||:|:.|||......
  Rat   195 NIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRVPP---DILVNWAVQIARGMNYLHDEAIVP 256

  Fly   130 VIHRDIKPLNT---------------LLCE------------KGLKLKICDFGTVVDLSQSISCN 167
            |||||:|..|:               .|||            ....|||.|||...:..::...:
  Rat   257 VIHRDLKSSNSECGELGWGEQHSLSLRLCEVLILQKVENGDLSNKTLKITDFGLAREWHRTTKMS 321

  Fly   168 -AGTCRYKAPEVLQGNKPDEKCDVYSWAITFWEILSRKEPFEQYNTLFELY-MAINEGERPDLSC 230
             |||..:.||||::.:...:..||:|:.:..||:|:.:.||...:.|...| :|:|:...|
  Rat   322 AAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLALP---- 382

  Fly   231 IMSGCPADIVALLYASWDPDISKRFSMELISQSMGRILSEAG--SIPPLDFY 280
            |.|.||.....|:...|:||...|.|...|...:..| .|:|  .:|...|:
  Rat   383 IPSTCPEPFAKLMEDCWNPDPHSRPSFSSILDQLTTI-EESGFFEMPKDSFH 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Takl2	NP_651090.2	S_TKc	14..258	CDD:214567	89/280 (32%)
Takl2	NP_651090.2	PKc_like	19..268	CDD:304357	89/285 (31%)
Map3k9	XP_038968662.1	SH3_MLK1-3	49..106	CDD:212992
Map3k9	XP_038968662.1	STKc_MLK1	130..419	CDD:271047	91/295 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810