DRSC/TRiP Functional Genomics Resources

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Protein Alignment Takl2 and Tnni3k

DIOPT Version :9

Sequence 1:NP_651090.2 Gene:Takl2 / 42692 FlyBaseID:FBgn0039015 Length:281 Species:Drosophila melanogaster
Sequence 2:NP_796040.3 Gene:Tnni3k / 435766 MGIID:2443276 Length:834 Species:Mus musculus


Alignment Length:291 Identity:84/291 - (28%)
Similarity:135/291 - (46%) Gaps:36/291 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 EIQTKELIGTGFYGSVYRAVWRNREIALKRIREG--CEDKKIE---REIYQLTKASHVNIVELYG 71
            ||:..|:||:|.:|.||:...||:.:|:||.|..  |....::   ||:..|.:.:|..:|:..|
Mouse   461 EIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVVQFVG 525

  Fly    72 TSRHEGCAL-LLMEFVDGGSLSSFLHAKSKPSYSHAHAFNWAHQIAQGIAYLHGM-QPKAVIHRD 134
            ....:.... ::.:::.||||.|.|| :.|...........|..:|:|:.|||.: ||  :||||
Mouse   526 ACLDDPSQFAIVTQYISGGSLFSLLH-EQKRILDLQSKLIIAVDVAKGMEYLHSLTQP--IIHRD 587

  Fly   135 IKPLNTLLCEKGLKLKICDFGTVVDL----SQSISCNAGTCRYKAPEVL-QGNKPDEKCDVYSWA 194
            :...|.||.|.|..: :.|||....|    ..:::...|..|:.||||. |..:...|.||:|:|
Mouse   588 LNSHNILLYEDGHAV-VADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYA 651

  Fly   195 ITFWEILSRKEPFEQYNTLFELYMAINEGERPDLSCIMSGCPADIVALLYASWD--PDISKRFS- 256
            :..||:|:.:.||.................||.:.   ...|..|.:||...|:  |:....|| 
Mouse   652 LCLWELLTGEIPFAHLKPAAAAADMAYHHIRPPIG---YSIPKPISSLLMRGWNACPEGRPEFSE 713

  Fly   257 -----------MELISQSMGRILSEAGSIPP 276
                       :||:|.:..   :.:||:.|
Mouse   714 VVRKLEECLCNVELMSPASS---NSSGSLSP 741

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Takl2NP_651090.2 S_TKc 14..258 CDD:214567 76/269 (28%)
PKc_like 19..268 CDD:304357 78/274 (28%)
Tnni3kNP_796040.3 ANK repeat 66..98 CDD:293786
ANK 1 66..96
Ank_2 71..164 CDD:289560
ANK 99..220 CDD:238125
ANK repeat 100..131 CDD:293786
ANK 2 100..129
ANK 3 133..162
ANK repeat 134..164 CDD:293786
Ank_2 138..231 CDD:289560
ANK 161..289 CDD:238125
ANK repeat 166..197 CDD:293786
ANK 4 166..195
ANK repeat 199..231 CDD:293786
ANK 5 199..229
ANK 228..359 CDD:238125
ANK 6 233..262
Ank_4 237..286 CDD:290365
ANK repeat 268..301 CDD:293786
ANK 7 268..297
Ank_2 273..368 CDD:289560
ANK repeat 303..336 CDD:293786
ANK 8 303..334
ANK 333..>400 CDD:238125
ANK repeat 338..368 CDD:293786
ANK 9 338..367
Ank_4 339..400 CDD:290365
ANK 10 380..409
TyrKc 462..718 CDD:197581 77/262 (29%)
PKc_TNNI3K 468..721 CDD:270966 75/259 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 815..834
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0192
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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