DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Takl2 and Map3k9

DIOPT Version :9

Sequence 1:	NP_651090.2	Gene:	Takl2 / 42692	FlyBaseID:	FBgn0039015	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	XP_017170611.1	Gene:	Map3k9 / 338372	MGIID:	2449952	Length:	1120	Species:	Mus musculus

Alignment Length:	292	Identity:	94/292 - (32%)
Similarity:	143/292 - (48%)	Gaps:	29/292 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VPYEEIQTKELIGTGFYGSVYRAVWRNREIALKRIR--------EGCEDKKIEREIYQLTKASHV 64
            :.:.|:..:|:||.|.:|.||||.|...|:|:|..|        :..|:.:.|.:::.:.|  |.
Mouse   132 IDFAELTLEEIIGIGGFGKVYRAFWAGDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLK--HP 194

  Fly    65 NIVELYGTSRHEGCALLLMEFVDGGSLSSFLHAKSKPSYSHAHAFNWAHQIAQGIAYLHGMQPKA 129
            ||:.|.|....|....|:|||..||.|:..|..|..|.   ....|||.|||:|:.|||......
Mouse   195 NIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRIPP---DILVNWAVQIARGMNYLHDEAIVP 256

  Fly   130 VIHRDIKPLNTLLCEK-------GLKLKICDFGTVVDLSQSISCN-AGTCRYKAPEVLQGNKPDE 186
            :||||:|..|.|:.:|       ...|||.|||...:..::...: |||..:.||||::.:...:
Mouse   257 IIHRDLKSSNILILQKVENGDLSNKILKITDFGLAREWHRTTKMSAAGTYAWMAPEVIRASMFSK 321

  Fly   187 KCDVYSWAITFWEILSRKEPFEQYNTLFELY-MAINEGERPDLSCIMSGCPADIVALLYASWDPD 250
            ..||:|:.:..||:|:.:.||...:.|...| :|:|:...|    |.|.||.....|:...|:||
Mouse   322 GSDVWSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLALP----IPSTCPEPFAKLMEDCWNPD 382

  Fly   251 ISKRFSMELISQSMGRILSEAG--SIPPLDFY 280
            ...|.|...|...:..| .|:|  .:|...|:
Mouse   383 PHSRPSFTSILDQLTTI-EESGFFEMPKDSFH 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Takl2	NP_651090.2	S_TKc	14..258	CDD:214567	87/260 (33%)
Takl2	NP_651090.2	PKc_like	19..268	CDD:304357	87/265 (33%)
Map3k9	XP_017170611.1	SH3_MLK1-3	49..106	CDD:212992
Map3k9	XP_017170611.1	STKc_MLK1	130..399	CDD:271047	89/275 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810