DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Takl2 and Tnni3k

DIOPT Version :9

Sequence 1:NP_651090.2 Gene:Takl2 / 42692 FlyBaseID:FBgn0039015 Length:281 Species:Drosophila melanogaster
Sequence 2:NP_861434.1 Gene:Tnni3k / 295531 RGDID:727908 Length:835 Species:Rattus norvegicus


Alignment Length:291 Identity:83/291 - (28%)
Similarity:136/291 - (46%) Gaps:36/291 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 EIQTKELIGTGFYGSVYRAVWRNREIALKRIREG--CEDKKIE---REIYQLTKASHVNIVELYG 71
            ||:..|:||:|.:|.||:...||:.:|:||.|..  |....::   ||:..|.:.:|..:|:..|
  Rat   462 EIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVVQFVG 526

  Fly    72 TSRHEGCAL-LLMEFVDGGSLSSFLHAKSKPSYSHAHAFNWAHQIAQGIAYLHGM-QPKAVIHRD 134
            ....:.... ::.:::.||||.|.|| :.|...........|..:|:|:.|||.: ||  :||||
  Rat   527 ACLDDPSQFAIVTQYISGGSLFSLLH-EQKRILDLQSKLIIAVDVAKGMEYLHSLTQP--IIHRD 588

  Fly   135 IKPLNTLLCEKGLKLKICDFGTVVDL----SQSISCNAGTCRYKAPEVL-QGNKPDEKCDVYSWA 194
            :...|.||.|.|..: :.|||....|    ..:::...|..|:.||||. |..:...|.||:|::
  Rat   589 LNSHNILLYEDGHAV-VADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYS 652

  Fly   195 ITFWEILSRKEPFEQYNTLFELYMAINEGERPDLSCIMSGCPADIVALLYASWD------PDISK 253
            :..||:|:.:.||.................||.:.   ...|..|.:||...|:      |:.|:
  Rat   653 LCLWELLTGEIPFAHLKPAAAAADMAYHHIRPPIG---YSIPKPISSLLIRGWNACPEGRPEFSE 714

  Fly   254 RFS--------MELISQSMGRILSEAGSIPP 276
            ..|        :||:|.:..   :.:||:.|
  Rat   715 VVSKLEECLCNVELMSPASS---NSSGSLSP 742

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Takl2NP_651090.2 S_TKc 14..258 CDD:214567 75/269 (28%)
PKc_like 19..268 CDD:304357 77/274 (28%)
Tnni3kNP_861434.1 ANK repeat 66..98 CDD:293786
ANK 1 66..96
Ank_2 71..164 CDD:289560
ANK 99..220 CDD:238125
ANK repeat 100..131 CDD:293786
ANK 2 100..129
ANK 3 133..162
ANK repeat 134..164 CDD:293786
Ank_2 138..232 CDD:289560
ANK 161..290 CDD:238125
ANK repeat 166..197 CDD:293786
ANK 4 166..195
ANK repeat 199..232 CDD:293786
ANK 5 199..228
ANK 229..360 CDD:238125
ANK 6 234..263
ANK repeat 234..262 CDD:293786
Ank_4 238..287 CDD:290365
ANK repeat 269..302 CDD:293786
ANK 7 269..298
Ank_2 274..369 CDD:289560
ANK repeat 304..337 CDD:293786
ANK 8 304..335
ANK 334..>401 CDD:238125
ANK repeat 339..369 CDD:293786
ANK 9 339..368
Ank_4 340..401 CDD:290365
ANK 10 381..410
TyrKc 463..719 CDD:197581 76/262 (29%)
PKc_TNNI3K 469..722 CDD:270966 74/259 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0192
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.