DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Takl2 and DSTYK

DIOPT Version :9

Sequence 1:	NP_651090.2	Gene:	Takl2 / 42692	FlyBaseID:	FBgn0039015	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_056190.1	Gene:	DSTYK / 25778	HGNCID:	29043	Length:	929	Species:	Homo sapiens

Alignment Length:	268	Identity:	74/268 - (27%)
Similarity:	114/268 - (42%)	Gaps:	31/268 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 IGTGFYGSVYRA-VWRNR-EIALKRI----REGCEDKKIEREIYQLTKASHVNIVELYGT---SR 74
            :|.|.||.||.. .|... ..|||.:    .:...|..:|.. |..:...|..:|:|:|:   ..
Human   658 LGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFH-YMRSLPKHERLVDLHGSVIDYN 721

  Fly    75 HEG----CALLLMEFVDGGSLSSFLHAKSKPSYSHAHAFNWAHQIAQGIAYLHGMQPKAVIHRDI 135
            :.|    ..||:||     .|...|:...|...:.......|..:.:||.:||.   :.::||||
Human   722 YGGGSSIAVLLIME-----RLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHS---QGLVHRDI 778

  Fly   136 KPLNTLLCEKGLKLKICDFGTVVDLSQSISCNAGTCRYKAPEVLQGNKPDEKCDVYSWAITFWEI 200
            |..|.|| :|..:.||.|.|.....:.......||..:.|||:..| |.|...|||::.|.||.|
Human   779 KLKNVLL-DKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTG-KYDNSVDVYAFGILFWYI 841

  Fly   201 LSRK----EPFEQYNTLFELYMAINEGERPDLSCIMSGCPADIVALLYASWDPDISKRFSMELIS 261
            .|..    |.||:..:...|:..:..|.||:...:..   .:...|:.|.||.|..||..:.::.
Human   842 CSGSVKLPEAFERCASKDHLWNNVRRGARPERLPVFD---EECWQLMEACWDGDPLKRPLLGIVQ 903

  Fly   262 QSMGRILS 269
            ..:..|::
Human   904 PMLQGIMN 911

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Takl2	NP_651090.2	S_TKc	14..258	CDD:214567	73/255 (29%)
Takl2	NP_651090.2	PKc_like	19..268	CDD:304357	73/265 (28%)
DSTYK	NP_056190.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		PKc_Dusty	651..912	CDD:270877	74/268 (28%)
		S_TKc	653..897	CDD:214567	72/252 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900