DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45049 and EMP1

DIOPT Version :9

Sequence 1:	NP_001287471.1	Gene:	CG45049 / 42691	FlyBaseID:	FBgn0266409	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_024304645.1	Gene:	EMP1 / 2012	HGNCID:	3333	Length:	192	Species:	Homo sapiens

Alignment Length:	202	Identity:	51/202 - (25%)
Similarity:	81/202 - (40%)	Gaps:	46/202 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 VIAFICGVIVV--ALMIMALAST---DWLMAS--DWRQGLFVHC---------------IEDDSV 130
            ::..:.|:.||  |.:||...||   .||:::  |...||:.:|               |..|..
Human     1 MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSDSLSYASEGIYKDID 65

  Fly   131 PPLPFNIQ---DPPG-----CYWTRDVG--YIKATAALCIITLITDVIATVLTGLGLRTQNHNLK 185
            |.|...:.   ..||     |. .|.|.  .:|...|..|:::|..|||.::....|.|..   |
Human    66 PVLTIGVVRECSAPGVTSCPCS-PRPVSTDALKTVQAFMILSIIFCVIALLVFVFQLFTME---K 126

  Fly   186 YKFYRIAVLVMLVSLLAVLSALIVYPVCFAGELTMANR--RVWEFGWAYGVGWGAAIFLF--GAV 246
            ...:.::....||..|.:|..:.:|...:      |||  ..:..|::|.:||....|.|  |.:
Human   127 GNRFFLSGATTLVCWLCILVGVSIYTSHY------ANRDGTQYHHGYSYILGWICFCFSFIIGVL 185

  Fly   247 VLLLCDK 253
            .|:|..|
Human   186 YLVLRKK 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45049	NP_001287471.1	PMP22_Claudin	<150..249	CDD:304458	25/104 (24%)
EMP1	XP_024304645.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000