Protein Alignment CG45049 and Tmem47

DIOPT Version :9

• Sequence 1: NP_001287471.1
• Gene: CG45049 / 42691
• FlyBaseID: FBgn0266409
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_620090.1
• Gene: Tmem47 / 192216
• MGIID: 2177570
• Length: 181
• Species: Mus musculus
• Alignment Length: 186
• Identity: 49/186 - (26%)
• Similarity: 90/186 - (48%)
• Gaps: 22/186 - (11%)

  Fly    80 ITITRPLKVIAFICGVIVVALMIMALASTDWLMAS-DWRQGLFVHCIEDDSVPPLPFNIQDPPGC 143
            :::..|||::..:|..:.:.|.:.|:.|..|:.|. .:...|:..|.:       |.|: |...|
Mouse    13 VSVLTPLKLVGLVCIFLALCLDLGAVLSPAWVTADHQYYLSLWESCRK-------PANL-DIWHC 69

  Fly   144 YWTRDVGYIKATAALCI----ITLITDVIATVLTGLGLRTQNHNLKYKFYRIAVLVMLVSLLAVL 204
            ..|....:..||.||.:    |.||..::..:...:|.|.       :|||...:::..:::..:
Mouse    70 ESTLGSDWQIATLALLLGGAAIILIAFLVGLISICVGSRR-------RFYRPVAVMLFAAVVLQV 127

  Fly   205 SALIVYPVCFAGELTMANRRVWEFGWAYGVGWGAAIFLFGAVVLLLCDKESEEIYY 260
            .:|::||:.|..  |::.:...||.|.||:.|||.||.||..:|...:.::.|.||
Mouse   128 CSLVLYPIKFIE--TVSLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKNYEDYY 181

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45049	NP_001287471.1	PMP22_Claudin	<150..249	CDD:304458	29/102 (28%)
Tmem47	NP_620090.1	PMP22_Claudin	21..170	CDD:419754	42/165 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839384
Domainoid	1	1.000	47	1.000	Domainoid score	I11967
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	66	1.000	Inparanoid score	I5340
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1307601at2759
OrthoFinder	1	1.000	-	-		FOG0007301
OrthoInspector	1	1.000	-	-		oto94351
orthoMCL	1	0.900	-	-		OOG6_107190
Panther	1	1.100	-	-	O	PTHR14399
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3171
SonicParanoid	1	1.000	-	-		X5405
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.930