Protein Alignment Irp-1A and ACO3

DIOPT Version :10

• Sequence 1: NP_477371.1
• Gene: Irp-1A / 42689
• FlyBaseID: FBgn0024958
• Length: 902
• Species: Drosophila melanogaster
• Sequence 2: NP_178634.2
• Gene: ACO3 / 815120
• AraportID: AT2G05710
• Length: 990
• Species: Arabidopsis thaliana
• Alignment Length: 886
• Identity: 535/886 - (60%)
• Similarity: 660/886 - (74%)
• Gaps: 15/886 - (1%)

  Fly    20 GNVYKYFDLPSI-DSKYESLPFSIRVLLESAVRNCDNFHVLEKDVQSILGWTPSLKQETSDVEVS 83
            |...|::.||:: |.:.:.||:|||:|||||:||||||.|.::||:.|:.|.   |.....||:.
plant   112 GEFGKFYSLPALNDPRVDKLPYSIRILLESAIRNCDNFQVTKEDVEKIIDWE---KTSPKQVEIP 173

  Fly    84 FKPARVILQDFTGVPAVVDFAAMRDAVRELGGNPEKINPICPADLVIDHSVQVDFVRSSDALTKN 148
            ||||||:||||||||||||.|.||||:.:||.:..||||:.|.|||||||||||..||.:|:..|
plant   174 FKPARVLLQDFTGVPAVVDLACMRDAMNKLGSDSNKINPLVPVDLVIDHSVQVDVARSENAVQAN 238

  Fly   149 ESLEFQRNKERFTFLKWGARAFDNMLIVPPGSGIVHQVNLEYLARVVFESDSSADGSKILYPDSV 213
            ..||||||||||.|||||:.||.|||:||||||||||||||||.||||.:..      :||||||
plant   239 MELEFQRNKERFAFLKWGSTAFQNMLVVPPGSGIVHQVNLEYLGRVVFNTKG------LLYPDSV 297

  Fly   214 VGTDSHTTMINGLGVLGWGVGGIEAEAVMLGQSISMLLPEVIGYRLEGKLGPLATSTDLVLTITK 278
            ||||||||||:||||.|||||||||||.||||.:||:||.|:|::|.||:....|:||||||:|:
plant   298 VGTDSHTTMIDGLGVAGWGVGGIEAEATMLGQPMSMVLPGVVGFKLAGKMRNGVTATDLVLTVTQ 362

  Fly   279 HLRQLGVVGKFVEFYGPGVAELSIADRATISNMCPEYGATVGYFPIDENTLSYMRQTNRSEKKID 343
            .||:.|||||||||||.|::.||:||||||:||.||||||:|:||:|..||.|::.|.||::.:.
plant   363 MLRKHGVVGKFVEFYGNGMSGLSLADRATIANMSPEYGATMGFFPVDHVTLQYLKLTGRSDETVA 427

  Fly   344 IIRKYLKATRQLRDYSLVDQDPQYTESVTLDLSTVVTSVSGPKRPHDRVSVSSMCEDFKSCLISP 408
            :|..||:|.....||:...||..|:..:.|:|..|...:||||||||||::..|..|:.|||.|.
plant   428 MIEAYLRANNMFVDYNEPQQDRVYSSYLELNLDDVEPCISGPKRPHDRVTLKEMKADWHSCLDSK 492

  Fly   409 VGFKGFAIPPSALAASGEFQWDDGKSYKIGHGSVVIAAITSCTNTSNPSVMLGAGLLAKNAVQKG 473
            |||||||||..|......|.: ||:..::.||||||||||||||||||||||||||:||.|...|
plant   493 VGFKGFAIPKEAQEKVVNFSF-DGQPAELKHGSVVIAAITSCTNTSNPSVMLGAGLVAKKACDLG 556

  Fly   474 LSILPYIKTSLSPGSGVVTYYLRESGVIPYLEQLGFDIVGYGCMTCIGNSGPLDENVVNTIEKNG 538
            |.:.|:|||||:|||||||.||.:||:..||.:.||:||||||.|||||||.::|:|...|.:|.
plant   557 LQVKPWIKTSLAPGSGVVTKYLLKSGLQEYLNEQGFNIVGYGCTTCIGNSGEINESVGAAITEND 621

  Fly   539 LVCCGVLSGNRNFEGRIHPNTRANYLASPLLVIAYAIAGRVDIDFEIEPLGVDSNGKEVFLRDIW 603
            :|...|||||||||||:||.|||||||||.||:|||:||.|:||||.||:|...|||:|||||||
plant   622 IVAAAVLSGNRNFEGRVHPLTRANYLASPPLVVAYALAGTVNIDFETEPIGKGKNGKDVFLRDIW 686

  Fly   604 PTRSEIQEVEHKHVIPAMFQEVYSKIQLGSRDWQTLEVSDSKLYPWSEISTYIKLPPFFEGMTRA 668
            ||..||.||....|:|.||:..|..|..|:..|..|.|.::.||.|...||||..||:|:.||..
plant   687 PTTEEIAEVVQSSVLPDMFRATYESITKGNPMWNKLSVPENTLYSWDPNSTYIHEPPYFKDMTMD 751

  Fly   669 LPKLKGIEKARCLLLLGDSVTTDHISPAGSIARKSPAARYLSERGLTPRDFNSYGSRRGNDAVMA 733
            .|....::.|.|||..|||:|||||||||:|.:.||||::|.|||:..:||||||||||||.:||
plant   752 PPGPHNVKDAYCLLNFGDSITTDHISPAGNIQKDSPAAKFLMERGVDRKDFNSYGSRRGNDEIMA 816

  Fly   734 RGTFANIRLVNKLAS-KTGPSTLHVPSGEEMDIFDAAERYASEGTPLVLVVGKDYGSGSSRDWAA 797
            ||||||||:||||.: :.||.|:|:||||::.:||||.||.|.|...:::.|.:|||||||||||
plant   817 RGTFANIRIVNKLMNGEVGPKTVHIPSGEKLSVFDAAMRYKSSGEDTIILAGAEYGSGSSRDWAA 881

  Fly   798 KGPFLLGIKAVIAESYERIHRSNLVGMGIIPLQFLPGQSADTLKLSGREVYNIVLPE--GELKPG 860
            |||.|.|:|||||:|:||||||||||||||||.|..|:.||||.|:|.|.|.|.||.  .|::||
plant   882 KGPMLQGVKAVIAKSFERIHRSNLVGMGIIPLCFKSGEDADTLGLTGHERYTIHLPTDISEIRPG 946

  Fly   861 QRIQVDAD-GNVFETTLRFDTEVDITYYKNGGILNYMIRKM 900
            |.:.|..| |..|..|:||||||::.|:.:||||.|:||.:
plant   947 QDVTVTTDNGKSFTCTVRFDTEVELAYFNHGGILPYVIRNL 987

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irp-1A	NP_477371.1	PTZ00092	1..901	CDD:240263	535/886 (60%)
ACO3	NP_178634.2	PLN00070	59..990	CDD:215047	535/886 (60%)