Protein Alignment Irp-1A and aco2

DIOPT Version :9

• Sequence 1: NP_477371.1
• Gene: Irp-1A / 42689
• FlyBaseID: FBgn0024958
• Length: 902
• Species: Drosophila melanogaster
• Sequence 2: NP_001011445.1
• Gene: aco2 / 496933
• XenbaseID: XB-GENE-1000785
• Length: 781
• Species: Xenopus tropicalis
• Alignment Length: 921
• Identity: 244/921 - (26%)
• Similarity: 374/921 - (40%)
• Gaps: 204/921 - (22%)

  Fly     1 MSGSGANPFAQFQESFTQDGNVYKYFDLPSIDSKYESLPFSIRVLLESAVRNCDNFHVLEKDVQS 65
            ||...||.:..::........|.|..|.|        |..|.:::..         |:.:...|.
 Frog    36 MSHFEANEYINYERLDKNINIVRKRLDRP--------LTLSEKIVYG---------HIDDPVTQE 83

  Fly    66 ILGWTPSLKQETSDVEVSFKPARVILQDFTGVPAVVDFAAMRDAVRELGGNPEKINPICPADLVI 130
            ::.....|:         .:|.||.:||.|...|::.|.:        .|.|   ....|:.:..
 Frog    84 VVRGKTYLR---------LRPDRVAMQDATAQMAMLQFIS--------SGLP---RVAVPSTIHC 128

  Fly   131 DHSVQV------DFVRSSDALTKNESLEFQRNKERFTFLKWGARAFDNMLIVPPGSGIVHQVNLE 189
            ||.::.      |..|:.|.           |:|.:.||...|..: .:....|||||:||:.||
 Frog   129 DHLIEAQLGGEKDLKRAKDI-----------NQEVYNFLATAAAKY-GVGFWKPGSGIIHQIILE 181

  Fly   190 YLARVVFESDSSADGSKILYPD-SVVGTDSHTTMINGLGVLGWGVGGIEAEAVMLGQSISMLLPE 253
            ..|                :|. .::||||||....|||.:..||||.:|..||.|....:..|.
 Frog   182 NYA----------------FPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPN 230

  Fly   254 VIGYRLEGKLGPLATSTDLVLTITKHLRQLGVVGKFVEFYGPGVAELSIADRATISNMCPEYGAT 318
            |||.:|.|:|....:..|::|.:...|...|..|..||::||||..:|....|||.||..|.|||
 Frog   231 VIGVKLTGQLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGAT 295

  Fly   319 VGYFPIDENTLSYMRQTNRSEKKIDIIRKYLKATRQLRDYSLVDQDPQYTESVTLDLSTVVTSVS 383
            ...||.:.....|:.:|.||        .......:.:.:.:.|:..:|.:.:.::|..:...::
 Frog   296 TSVFPYNHRMKKYLDKTGRS--------AIASLADEFKSHLVPDEGCEYDQLIEINLDELKPHIN 352

  Fly   384 GPKRPHDRVSVSSMCEDFKSCLISPVGFKGFAIPPSALAASGEFQWDDGKSYKIGHGSVVIAAIT 448
            ||..|.               |.:||...|      |:|....:..|           :.:..|.
 Frog   353 GPFTPD---------------LANPVSEVG------AVAEQKGWPLD-----------IRVGLIG 385

  Fly   449 SCTNTSNPSVMLGAGLLAKNAVQKGLSILPYIKTSLSPGSGVVTYYLRESGVIPYLEQLGFDIVG 513
            ||||:|... |..|..:||.|:..||....  :.:::|||..:...:...|....|..:|..::.
 Frog   386 SCTNSSYED-MGRAAAVAKQALAHGLKCKS--QFTITPGSEQIRATIERDGYAAVLRDVGGVVLA 447

  Fly   514 YGCMTCIGNSGPLDENVVNTIEKNGLVCCGVLSGNRNFEGR--IHPNTRANYLASPLLVIAYAIA 576
            ..|..|||.   .|...:...|||.:    |.|.||||.||  .:|.|.| ::.||.:|.|.:||
 Frog   448 NACGPCIGQ---WDRKDIKKGEKNTI----VTSYNRNFTGRNDANPETHA-FVTSPEIVTALSIA 504

  Fly   577 GRVDIDFEIEPL-GVDSNGKEVFLRDIWPTRSEIQEVEHKHVIPAMFQEVYSKIQLGSRDWQTLE 640
            |.:..|.|.:.| |.|  ||:..|:.  |...|:.:        :.|.......|...::..:|:
 Frog   505 GTLKFDPEKDFLTGAD--GKKFKLQP--PDADELPK--------SSFDPGQDTYQHPPKEGSSLK 557

  Fly   641 VSDSKLYPWSEISTYIKLPPF--FEGMTRALPKLKGIEKARCLLLLGDSVTTDHISPAGSIARKS 703
            |..|   |.|:  ....|.||  ::|        |.:|..:.|:.:....||||||.||
 Frog   558 VDVS---PTSQ--RLQLLEPFDKWDG--------KDLENMQILVKVKGKCTTDHISAAG------ 603

  Fly   704 PAARYLSERGLTPRDFNSYGSRRGN-DAVMARGTFANIRLVNKLASKTGPSTLHVPSGEEMDIFD 767
            |..::                 ||: |.:........|.|.|..|:    |..:..:.|...:.|
 Frog   604 PWLKF-----------------RGHLDNISNNLLIGAINLENNKAN----SVKNCVNQEYGAVPD 647

  Fly   768 AAERYASEGTPLVLVVGKDYGSGSSRDWAAKGPFLLGIKAVIAESYERIHRSNLVGMGIIPLQFL 832
            .|..|.:.|...|::..::||.||||:.||..|..||.:|:|.:|:.|||.:||...|::||.|
 Frog   648 TARYYKAHGIKWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTF- 711

  Fly   833 PGQSADTLKLSGREVYNIVLPE-----GELK---PGQRIQ--VDADGNVFETTLRFDT--EVDIT 885
             ...||         |:.:.||     .|||   ||:.::  :.......||.|...|  |..|.
 Frog   712 -SDPAD---------YDKIHPEDKITIAELKHLAPGKPVKCIITHQNGSQETILLNHTFNETQIE 766

  Fly   886 YYKNGGILNYM 896
            :::.|..||.|
 Frog   767 WFQAGSALNRM 777

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irp-1A	NP_477371.1	PTZ00092	1..901	CDD:240263	244/921 (26%)
		AcnA_IRP	88..579	CDD:153136	140/499 (28%)
		AcnA_IRP_Swivel	683..852	CDD:238812	49/169 (29%)
aco2	NP_001011445.1	aconitase_mito	47..777	CDD:273561	239/908 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D190960at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010