|
Fly 7 GASSSAADVLSATTATATFLVPTTAAVSHPGAHT--------AHLQLDQFGGFSAATAT------ 57
|.||.......|..|| .|| :|:|.|..| :..|..:.||.|....|
Zfish 434 GISSGGCRDPKANGAT---FVP---SVNHLGEKTRGPFQMGNSECQGVEGGGNSVKDKTMEKNGN 492
Fly 58 -------PLQHHHHQQTNSSYTFVQIKREPCQVSEISSNNCHQQQQQHHQHHQHQVQHQGLSSAS 115
|.:......|...:.:.:.::.|..:.. .:::.|.||||..|...|..|||.:.|.|
Zfish 493 GGHHGNWPRKQQQQPPTQQQHPYRKAEKAPDWMHN-HNHHHHIQQQQQQQQQSHPQQHQSVRSRS 556
Fly 116 ---MTASSKTMSSSTLTTLVKIEAPSPKVSELEKSTGNSVPI----------------------- 154
:.:....:..|||:...|...|.| .::|.||.|.
Zfish 557 ADCINSMETDIFRSTLSQETKAVHPLP-----NQTTTNSQPYRDCSHSGPPTIPSPLAGKTMAQH 616
Fly 155 --------------GIAVARKRPQEALVPAINTPATLPLQPPLNKDLNCFGIRVADLGATSCGNL 205
|..|||.|.|:......:||.| |:...:
Zfish 617 AGGGGHGSCSMQRDGQKVARIRHQQHSRAGPDTPGT-------------------DMAQAN---- 658
Fly 206 YFTGNGDLMTTGTATAEELALSAAGVNRAPSTFWQYPNALPIESVISMSPATVGLQYSREASRGQ 270
||.:: .:::.:|..|.| :....:|:..|.....:|.|..: ..|.::.:
Zfish 659 ---GNQEM-------KQKMEMSPYGYN---NNAQHHPHQQPSVPPWAMQPHHI----HSEENQHK 706
Fly 271 VVLLPAGPTALGISNFPLLTPTDPFQQAAAAAAFVWPSAYIPQAPAPGGH------SAAAAAAAA 329
..:.|....| :|.| |.||....|....|.. |..|||..: |....:|..
Zfish 707 AYMEPNSGAA---NNRP------PTQQQHQTAGMGPPPP--PLHPAPPQNQQEVSGSQGENSAMK 760
Fly 330 SLQPTPNLSSLPNFIFPSMGGHQALSTTPSYAS-TLQ---------------------------- 365
:|....|..|||.......||..:|.|.|:..| :||
Zfish 761 NLLKYSNQQSLPLSQKSPFGGLGSLKTGPNGTSCSLQGGKQTLPSRKGQSHENERGDCGGRGREM 825
Fly 366 ---LYL----------AAAATATGSSTMCQHSNQQTSTT-------------------------- 391
.:| .|.|.|......||.|....|:.
Zfish 826 GEAQHLEGEVRQPPVGIAVAVARQRDPPCQASGSHPSSRQGRVHSTMKGTPRSMYPSDLPGEEER 890
Fly 392 ----------------------------------TTNS-----TINLSLAAGSGVTQSGNAASSL 417
.:|| |.::.:..|:.: |||......
Zfish 891 KRTSIEHMGHRCIERERDAYIRDNKERVEFAHIHPSNSCHGDLTSHIMVPGGTSM-QSGQLGDPA 954
Fly 418 SSSSSL-------SASSSRFL---SLATGQTGIPSLLSLPPPTGLKEEYPMPLALPPLVPL---- 468
|.|.|. :.|.|.:: |...|.|.:.. :||| |.....|.| |.|::||
Zfish 955 SHSHSAHHHWMPRTGSPSLWMTGHSYGIGHTALHQ--NLPP--GFSAAMPAP--LQPVLPLPQDP 1013
Fly 469 ---------EAARDKEQALNLMRLP--TPPT-------SATMEPS-------------------- 495
|.|......|::|..| .||. |....||
Zfish 1014 STQLVVLPSEPATHPSTHLDVMEQPGLWPPVYRARGAHSHMQHPSVYPRSQFLRQQELYALQQHQ 1078
Fly 496 SLGHA--TPHHLFQSGAMATPTPALLNLSMH--GNGGELPAA-----TPLPAVSDEAALNYK--L 549
.|.|. ..|| ||.| ..| .|..||... :.:...|:|.::..: |
Zfish 1079 QLQHQQHPSHH--------TPPP-----QTHRAANNTELQQRDTADHSQVQKKSEEQSMELEDIL 1130
Fly 550 HAPLTPQTPPRL--------ADIPVSGSTQLL---------------------PQMQDVNIQTDT 585
..|.||: ||:. ...|..|||..| |....|.:...:
Zfish 1131 SDPRTPK-PPKCYGYGPSSRVSSPARGSTAHLSPCCQSPCMRPHPKSTPSTPCPAPSPVAVTPCS 1194
Fly 586 PVCSEDES--------------------FPGSAKPQDPAAEAFP---------PPTHVQPLELTK 621
|..|...| :|.|.:|..|....:| |.| |.::||:
Zfish 1195 PAISPSPSQRLKSVESQEKRVEGQPPQDYPQSMEPDLPPGYTYPEINMGYRNGPMT--QDVQLTE 1257
Fly 622 P-------SEA-SHTQPT--------ECHTQTEPSDIPSAS-------------------QEESA 651
| ||| .||.|| |||....|...|.|. |.|..
Zfish 1258 PADLQPVRSEAVEHTSPTLSSLGEGLECHAMVRPLQEPQAPTMEVDATSLVEEQHEGVFVQGEDV 1322
Fly 652 EQTPP----EPIETMTQATQADQTS-PEDLTGLELLSNISTNSKPLVRVKQEPV----EHIEQPA 707
|.... ||:|...:...|:... |:::...|:..:.:.:|:.::. ::||: |.:|:..
Zfish 1323 ETVMAMGCCEPVEANQEKEHAEIICVPDEVQDCEVGQSPTLSSEEVIH-EEEPIASFEERVEKDI 1386
Fly 708 PQPQPV----NIMPSEPTLPMPPML-EMEPTSEREPLGGLKLLCALAEQRIQEEVVQGSSLFATP 767
| ||.. .:...||.|...|.. :..||::.| :..|.||....:.....|
Zfish 1387 P-PQETEGIETVNDLEPPLTQKPCASDCSPTTQEE------------DAVIVEEDQGSNCTMVAP 1438
Fly 768 S-------SRTPTPTSLALGTTAA----TPPIFEAKSCYAFGQSQGSVFPSSTSSFQM-----PL 816
| |.|.:..||.|...|| .|| ||..||:|. ||
Zfish 1439 STSNTCSQSLTSSYWSLELLIAAAFCGDCPP------------------PSPPSSYQSQKSCGPL 1485
Fly 817 SSPGFPSMQGIELPTTSAGIVAELTPVKRKKHKHSKSSGSD-----------------------S 858
:| :..|:|| ::||..::.:::..|.|...: |
Zfish 1486 NS----TYHGMEL-------LSELADLELQRYHQSCSKTQEEDQWIFDLQSLATLAAARALELGS 1539
Fly 859 RKSARCSKKSKKKRHHSSSRQQFS-APAEEDLDLQDDQLQSELRNALHAVDPSYAQRFGQEVFSI 922
::|....:|....|...:.|::.| .|..|.: ..::..:.::| |||:
Zfish 1540 QESVTTDEKQYPARRTLNLRRKCSWTPRHEPV--------CPVKGTMDSMD-------GQEL--- 1586
Fly 923 MDNSMRMRLAKITRQYRKKKRKLDEIS-KHKKKKKCSKQQLELQQQQASQQAVQP---------- 976
.||:|||::.::|::|:::|.::. ||..:|: |..:..|.:...:|
Zfish 1587 ---EMRVRLAELQQRYKEKQKELAKLQRKHDHQKE------ETPRSPARRGPGRPRKRKSVPGLG 1642
Fly 977 SSALQQPQMTLSSVLGTSSPLRDYK--------------FPKFSSSNLQASSF------------ 1015
|.||.:||..:..|....|||.:.: |.:.||:.:::..:
Zfish 1643 SGALTEPQKKVKLVGAGLSPLAEERGDSQKKRKKLSNRGFSRLSSAQMKSQCYRKNSTIDQQITQ 1707
Fly 1016 ----------------------------------------------------------------- 1015
Zfish 1708 LKQRVPGGQHTSGTTASKSLYSGHSSSKRDSAQLSTANESESLSDTATSGDSGTQESWKRHESVA 1772
Fly 1016 -------------------LRFP-------DKTHSFPPPPSLQQSQPEPNP-------------- 1040
.|.| |:.....||.|....|.|...
Zfish 1773 GKRERKKSPGATACLQQPGARIPQGRRQEVDEDGETSPPESESSEQEEEEEEGSYGSEEGQDVKA 1837
Fly 1041 --------LPSSSSPSTSSFVRLE----------------------------------------- 1056
.|:.:.||..|.|:||
Zfish 1838 PAFRDLSFSPAVTGPSPFSVVKLEANQKAKIKRERQELYGSQFHAVTAGDVKVKQRTPCRSVPIT 1902
Fly 1057 ----PSA-----------------------LDAAVAIAPTTSSTSTSGSPSTKQVASARKQRKMK 1094
||| ...:.::.|..||:|.....:|::.:..|..|:..
Zfish 1903 VSKPPSARRRPGRPRLQDKRWSGMAGRPGHYRKSSSLLPFPSSSSERLKRATRKTSMLRATRRSY 1967
Fly 1095 ASTVGAAGE--------QTAATEAKRR----------------------FSAIDRELQLT----- 1124
.||...:.: :|...|:|.| ||..|.|.:::
Zfish 1968 WSTKAQSPDSDDNGSTRRTRLRESKGRAVSRLMESFAADEGFHLGEDSSFSEEDEERKVSASCRI 2032
Fly 1125 ---------SEHLYRDETRVL-TDMGGLFYAGVMKPLRPPDVYSITLDGERGNKSHVMSREDILK 1179
::.|..|..::| :....|.||..::||..||||||.:||||||:..|.|.|.:|:
Zfish 2033 APAPPNCVLTKELLTDGLKILISKEDELLYAARVQPLESPDVYSIVIDGERGNRPRVYSLEQLLQ 2097
Fly 1180 DTILEVAPKSVESVPVGTRLCAYWSQQYRCLYPG---RAIDSEQVVDGTASSATNAATTAPDFVS 1241
:.:|:|.|.:...:..|||:|||||::.|||||| |..|..: |..|.
Zfish 2098 EAVLDVRPDTETVLTEGTRVCAYWSERSRCLYPGYVRRGGDESK----------------PGGVM 2146
Fly 1242 VEFDDGDSGRIRLQNIRMLLSDYPIAEYNDNP--------------------------------- 1273
|||||||.|.|.|.|||.|...|.|.....:|
Zfish 2147 VEFDDGDRGWISLSNIRFLPPGYQIQCTESSPALIPEVHLSKNSSEQESRTVSEKMARADRFKSQ 2211
Fly 1274 ---LYSVGKQKRSALRG------GESGPGGVTQDHLTVPGCE----------------------- 1306
:...|:.|.|.|:. .:|....:|...:..|...
Zfish 2212 EKTVRRPGRPKGSGLKKSLSDTVAKSSASALTWPSVAAPRKRMPVNFFQLNGSTSKKTLKSRVVE 2276
Fly 1307 ------------------------DSHSHHSLGMSSDNTTSLAATME-LFTQRSEKKRLKKS--- 1343
||.|..:.|.||..:.:...::| ..|..|:||:.::|
Zfish 2277 ISSRPTVSMTTPTKGLFSSSSFEVDSFSSIANGYSSFGSQTSGISLEGKNTSYSQKKKAEESAPP 2341
Fly 1344 -------LKKMSKAQNGV-SPATATN-----------GGADAAAL------------------GD 1371
|.|:. ..|| ||.|..: |.:...:| ||
Zfish 2342 RGRKVEFLVKLD--HEGVTSPKTKNSKALLLLGASGFGSSGVGSLPRAEVYSHPVLLVKDNRKGD 2404
Fly 1372 GVSAEDAARKHHKHKKRKK--------------HKKHHRKNGSEEQEQQVVQQDYSA-------- 1414
|..||...::....||... |:.........::|:..::.|.:|
Zfish 2405 GSRAELLLKRTSIQKKASPSLHLNEYGDLNLGCHRDCQSSYSDMDEEEVEIRTDSNALASASGGL 2469
Fly 1415 --AGQ--------EATEAPSTEMSSATSSRVKVEVKVKTEQLEMEEEESASNLMSEIS------- 1462
||| .::...|:..||.:.|...:...........|:|||::.|:....
Zfish 2470 RTAGQFLSRISVSSSSSGSSSSSSSGSLSSSSLCSSDNDSSYSSEDEESSTLLLQSCMTPHHSML 2534
Fly 1463 ---------------------DEAKGDDLVEHNNSKGSS-------------------------- 1480
..|||. :.|::.||.
Zfish 2535 QTTEAPVGPSRHTFVAKAVAVSSAKGG---QSNHNTGSKQLKRKECASSLSKSSKDLVKRQRLLA 2596
Fly 1481 -----KIAAFLPERQLWGWYGTAYRKAGVKGRARKQFYKTIKRGKETITVGDSAVFLSTGRPDRP 1540
:::..||.||||.|.|...::.|:||:|||.|||.|.|||:.:.|||.|||||||.|..|
Zfish 2597 DQTKPRVSPILPPRQLWRWSGNPTQRRGLKGKARKLFYKAIVRGKDIVRVGDCAVFLSTGHPPLP 2661
Fly 1541 YIGRIESMWETTTGNKVVRVAWFYHPEET-TGCPKLKFPGALFESPHEDENDVQTISHRCEVLQF 1604
.||||||.||:...:.||:|.|||||||| .|........||::|.||||||||||||:|:|:.
Zfish 2662 LIGRIESFWESWQNSMVVKVKWFYHPEETKLGKRHRDGKHALYQSCHEDENDVQTISHKCQVVT- 2725
Fly 1605 GSYFEKFGADSKQYQSIYDNNDTYYLAGHYNPRLQVLKLQDDIPTL 1650
.|::...::..:|....:|.|||||.|:|....|...|.:..|
Zfish 2726 ---CEEYDRLTRNRKSDGSYHDLYYLAGTYDPTSGQLLTADGMSIL 2768
| 
