|
Fly 34 SHPGAHTAHL--QLDQFGGFSAATATPLQHHHH---QQTNSSYTFVQIKREPCQVSEISSNNCHQ 93
|.||....|| |..|.||..| |..|.|. .:|.|...::
Human 791 SCPGDLAPHLMMQSGQLGGDPA----PHTHPHPPWLPRTRSPSLWM------------------- 832
Fly 94 QQQQHHQHHQHQVQHQGLSSASMTASSKTMSSSTLTTLVKIEAPSPKVSELEKSTGNSVPIGIAV 158
..|.....|...||.| .....|| :..|.|.|..|
Human 833 --GGHSYGLGHPALHQNL-PPGFPAS--------------VAGPVPSVFPL-------------- 866
Fly 159 ARKRPQEA-----LVPAINTPATLP-----------LQPPLNKDLNCFGIRVADLGATSCGNLYF 207
||:| ::|:..||.:.| |.||: :|
Human 867 ----PQDAPTQLVILPSEPTPHSAPHALADVMDQASLWPPM------YG---------------- 905
Fly 208 TGNGDLMTTGTATAEELALSAAGVNRAPSTFWQYPNALPIES--VISMSPATVGLQYSREAS--- 267
.|.|::..|:|..||:.| .:........||..|.|.
Human 906 ------------------------GRGPASHMQHPGQLPVYSRPQLLRQQELYALQQQRAAQFQR 946
Fly 268 --RGQVVLL--PAGPTALGISNFPL-LTPTDPFQQAAAAAAFVWPSAYIPQAPAPGGHSAAAAAA 327
..|.:.| ||...|...::.|: ||||.|...:.||.....|....|..|.|...|
Human 947 KPEDQHLDLEEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASS------ 1005
Fly 328 AASLQPTPNLSSLPNFIFPSMGGHQALSTTPSYASTLQLYLAAAATATGSSTMCQHSNQQTSTTT 392
||| ...||...||.:..|::..........:..|.:...:|
Human 1006 -----PTP-------------------PPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQST 1046
Fly 393 TNSTINLSLAAGSGVTQSGNAASSLSSSSSLSASSSRFLSLATGQTGIPSLLSLPPPTGLKEEYP 457
.:...:..:|....|..:| ...|:|:...:::|..| ||..| ||..|:....
Human 1047 ADIITSEPVARAHSVAHAG--LEFLASNDPSTSASQSF--------GITDL----PPGYLRPMAG 1097
Fly 458 MPLALPPLVPLEAARDKEQALNLMRLPTPPTSATMEPSSLGHATPHHLFQSGAMATPTPALLNLS 522
:..:||..|......|.|..........|..:.|..|......:|..|.:.|.::....|..:|
Human 1098 LGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDL- 1161
Fly 523 MHGNGGELPAATPLPAVSDEAALNYKLHAPLTPQTPP-RLAD-IPVSGSTQLLPQMQ-DVNIQTD 584
||||.| |.:.|. :.|| .|:.| |.::| ...::..
Human 1162 ---------AATPYP----------------TERGPQGKAADPSPLEG----LQELQCAALLEAG 1197
Fly 585 TP-VCSEDESFPGSAKPQDPAAEAFPPPT---HVQPLELTKPS----EASHTQPTECHTQTEPSD 641
.| ...:..|..|.|:.:....|....|: ..|.||....| |....||.....:.|..:
Human 1198 GPEATGQAHSTQGGAREERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDE 1262
Fly 642 IPSASQEESAEQTPPEPIETMTQATQADQTSPEDLTGLELLSNISTNSKPLVRVKQEPVEHIEQP 706
:...|.|:|.|.....| .:...|..|.||:.|...:.|...| |.: ..|
Human 1263 LGQQSMEDSEEDCGGAP---------DNSHPPRALPGLDALVAATINLGDL------PSD--SPP 1310
Fly 707 APQPQPVNIMPSEPTLPMPPMLEMEPTSEREPLGGLKLLCALAEQRIQ------------EEV-- 757
.|||...:..|| |:|:| ....:.|:.||..||:..|| |:|
Human 1311 DPQPPAASGPPS--TVPLP---------HSSGIHGIALLSELADLAIQRQRSERTVPEEEEDVLA 1364
Fly 758 --VQGSSLFATPSSRTPTPTSLALGTTAATPPIFEAKSCYAFGQSQGSVFPSSTSSFQM------ 814
:|..:..||..|.... ..|...|..|.|| .|..|.. |..|...|:
Human 1365 FNLQHLATLATAWSLVEA-AGLDSSTAPAQPP--TANPCSG---------PRLTPRMQILQRKDT 1417
Fly 815 --PLSSPGFPSMQGIE-LPTTSAGIVAELTPVKRK-----------KHKHSKSSGSDSRKSARCS 865
|.:.|..|....|: |.|...|:...|..::|: :.||.......||..||..
Human 1418 WTPKTKPVCPLKAAIDRLDTQEVGMRVRLAELQRRYKEKQRELARLQRKHDHERDESSRSPARRG 1482
Fly 866 KKSKKKRHHSSSRQQFSAP----------------AEEDLDLQDDQL-----------QSELRNA 903
....:||.|||| ..|| ....|.|...:| :|:|..:
Human 1483 PGRPRKRKHSSS---LPAPRPTGPLPRSDGKKVKAVRTSLGLLCAELRGGSGGEPAKKRSKLERS 1544
Fly 904 LHA--------------------VDPSYAQRFGQEVFSIMDNSMRMRLAKITRQ----------- 937
::| :.||.|.|..|....:....:...|:...::
Human 1545 VYAGLQTASVEKAQCKKSSCQGGLAPSVAHRVAQLKPKVKSKGLPTGLSSFQQKEATPGGRIREK 1609
Fly 938 -YRKKKRKLDEISKHKKKK--------KCSKQQLELQQQQA------------------------ 969
.|.|..|:...::|.:.| :|..|......|:|
Human 1610 LSRAKSAKVSGATRHPQPKGHGSRETPRCPAQPSVAASQEAGSGYDSEDCEGLLGTEAPPREAGL 1674
Fly 970 -----SQQAV---QPSSALQ-------QPQMTLSSVLGT---SSPLRDYKFPKFSSSNLQASSFL 1016
:..|| .|||.:: :.:.....:||. |||..:.|..:.|......::..
Human 1675 LLHTGASVAVLGPSPSSVVKMEANQKAKKKKERQGLLGACRLSSPESEVKIKRRSVKAKVGTTLE 1739
Fly 1017 RFPDKTHSFPPPPSLQQS----------QPEPNPLPSSS---SPSTSSFVRLEPSAL-------- 1060
|.|.:. ||.:|.:. :.||...||.. :||.:...|.|.|.|
Human 1740 RAPGQR----PPGALGKKKAKGKAKGSLRAEPGATPSRDALFNPSRAFACREEGSQLASERLKRA 1800
Fly 1061 --------------DAAVAIAPTTSSTST---SGSPSTKQVASARKQRKMKASTVGAAGEQTAAT 1108
:.|::|...|.:... .|...:|....|.||.|.:| |....|..|..
Human 1801 TRKGTVLQPVLRRKNGALSITLATRNAKAILGKGRKLSKVKHKAGKQGKGRA--VSRLLESFAVE 1863
Fly 1109 E---------------------------AKRRFSAIDRELQLTSEHLYRDETRVLTDM-GGLFYA 1145
| :..:.:|:.|...:..|.| ||...||... ..|.||
Human 1864 EDFEFDDNSSFSEEEEDEEEEEEDSGPLSAEQSAALARSCAIHKEDL-RDGLPVLIPKEDSLLYA 1927
Fly 1146 GVMKPLRPPDVYSITLDGERGNKSHVMSREDILKDTILEVAPKSVESVPVGTRLCAYWSQQYRCL 1210
|.::.|:|||:|||.::|||||:..:.|.|.:|::.:|:|.|:|...:|.|||:||||||:.|||
Human 1928 GSVRTLQPPDIYSIVIEGERGNRQRIYSLEQLLQEAVLDVRPQSSRYLPPGTRVCAYWSQKSRCL 1992
Fly 1211 YPGRAIDSEQVVDGTASSATNAATTAPDFVSVEFDDGDSGRIRLQNIRMLLSDYPI--------- 1266
||| .||.|.:....... |.|.|||||||:|.|.:.|:|:|..|:.|
Human 1993 YPG------NVVRGASGDEDEDL----DSVVVEFDDGDTGHIAVSNVRLLPPDFKIQCTEPSPAL 2047
Fly 1267 -----------------------------------------------------AEY--------- 1269
||.
Human 2048 LVSSSCRRTKKVSSEAPPPSEAATPSLSPKAQDGPEALKTPGKKSISKDKAGKAELLTSGAKSPT 2112
Fly 1270 ---------NDNPLYS---VGKQKRSALRGGESGPGGVTQDHLTVPGC-------EDSHSHHSL- 1314
..:||.| |.:.||.|:.....|| ||.|:...:.|. |.....||:
Human 2113 GASDHFLGRRGSPLLSWSAVAQTKRKAVAAASKGP-GVLQNLFQLNGSSKKLRAREALFPVHSVA 2176
Fly 1315 ------GMSSDNTTSLAATMELFT-------QRSEKKRLKKSLKKMSKAQNG------------- 1353
|..:|:.:|||::...|. .|...|.|:....:..:|:.|
Human 2177 TPIFGNGFRADSFSSLASSYAPFVGGTGPGLPRGAHKLLRAKKAERVEAEKGGRRRAGGEFLVKL 2241
Fly 1354 -----VSPATATNGGADAAALGDGVSAEDAARK--------HHKHK----KRKKHKK-------- 1393
.||...| ..|..:|| :|.:.| .:.|. |.||.:.
Human 2242 DHEGVTSPKNKT---CKALLMGD----KDFSPKLGRPLPSPSYVHPALVGKDKKGRAPIPPLPMG 2299
Fly 1394 -HHRKNGSEEQEQQVVQQD-YSAAGQEATEAP--------------STEMSSATSSRVKVEVKVK 1442
..||...:.:.......| :|:...|..:.| |...||:.||.......|.
Human 2300 LALRKYAGQAEFPLPYDSDCHSSFSDEDEDGPGLAAGVPSRFLARLSVSSSSSGSSTSSSSGSVS 2364
Fly 1443 TEQLEMEEEESASNLMSEISDEA-----------------------KGDDLVEH----------- 1473
|..|...:.|. |:..|:..|.| ||.....|
Human 2365 TSSLCSSDNED-SSYSSDDEDPALLLQTCLTHPVPTLLAQPEALRSKGSGPHAHAQRCFLSRATV 2428
Fly 1474 ----------NNSKGS---------------------------SKIAAFLPERQLWGWYGTAYRK 1501
::||.. .||:||||.||||.|.|...::
Human 2429 AGTGAGSGPSSSSKSKLKRKEALSFSKAKELSRRQRPPSVENRPKISAFLPARQLWKWSGNPTQR 2493
Fly 1502 AGVKGRARKQFYKTIKRGKETITVGDSAVFLSTGRPDRPYIGRIESMWETTTGNKVVRVAWFYHP 1566
.|:||:|||.|||.|.||:||:.|||.|||||.|||:.|||||||||||:...|.||:|.|||||
Human 2494 RGMKGKARKLFYKAIVRGEETLRVGDCAVFLSAGRPNLPYIGRIESMWESWGSNMVVKVKWFYHP 2558
Fly 1567 EET-TGCPKLKFPGALFESPHEDENDVQTISHRCEVLQFGSYFEKFGADSKQYQSIYDNNDTYYL 1630
||| .|..:.....||::|.||||||||||||:|:|:....|.:. |.|::.| |..|.|||
Human 2559 EETKLGKRQCDGKNALYQSCHEDENDVQTISHKCQVVAREQYEQM--ARSRKCQ---DRQDLYYL 2618
Fly 1631 AGHYNPRLQVLKLQDDIPTL 1650
||.|:|....|...|.:|.|
Human 2619 AGTYDPTTGRLVTADGVPIL 2638
| 
