DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4907 and enpp1

DIOPT Version :9

Sequence 1:	NP_651086.1	Gene:	CG4907 / 42686	FlyBaseID:	FBgn0039010	Length:	919	Species:	Drosophila melanogaster
Sequence 2:	XP_005160498.1	Gene:	enpp1 / 562399	ZFINID:	ZDB-GENE-040724-172	Length:	878	Species:	Danio rerio

Alignment Length:	311	Identity:	59/311 - (18%)
Similarity:	105/311 - (33%)	Gaps:	101/311 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SIYFQSTILSDLE--PLSTLRELGLEPPADRLVVFVVDGLRAQSVLADHCSAVPDLRELFVEQAL 81
            ::||:....|..:  |:|| :.:......|||:..::|||:.:::
Zfish   336 TLYFEEPDASGHKYGPMST-QVIEALINVDRLIGMLMDGLKERNL-------------------- 379

  Fly    82 VGISRACPPTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVF-THLP 145
                ..|...|....|     |..|.......:..:..|::     |.|..:|...|:|. .|:|
Zfish   380 ----HKCVNVVLVSDH-----GMEEASCKKAAYVSNYLDNI-----NDITVIQGPAARVRPRHVP 430

  Fly   146 TGGAPLRFETFARSDISDRLRLDQWTFD---KVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAE 207
                    |.|             ::||   .|:|....|.| ||::.        ||.:
Zfish   431 --------EEF-------------FSFDYEGLVKNLSCREPN-QPMKP--------YLKE----- 460

  Fly   208 HVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYGISLHGGGGE-RGVETPFIL 271
              |:|..|:|.:.:. .:|........:::....|...|...     ..||.... :.::..||.
Zfish   461 --HLPKRLHFAKNIR-IERAHLYMQPQWQAALKPSEIKYCRG-----GFHGSDNVFKNMQAIFIG 517

  Fly   272 WGAGVKRSAPNPGQNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPPMNN 322
            :|.|:..:...|                ..|.|::..|:..|:|:.|..||
Zfish   518 YGPGIHYNTTVP----------------PFENIEVYNLLCDLLGISPAANN 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4907	NP_651086.1	GPI_EPT_1	42..327	CDD:293744	53/286 (19%)
CG4907	NP_651086.1	PigN	413..858	CDD:282796
enpp1	XP_005160498.1	Somatomedin_B	70..108	CDD:279385
		SO	112..155	CDD:197571
		Enpp	177..545	CDD:293742	55/302 (18%)
		Phosphodiest	179..505	CDD:279931	46/246 (19%)
		NUC	644..862	CDD:294067
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900