DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4907 and enpp7.1

DIOPT Version :9

Sequence 1:	NP_651086.1	Gene:	CG4907 / 42686	FlyBaseID:	FBgn0039010	Length:	919	Species:	Drosophila melanogaster
Sequence 2:	NP_001243734.1	Gene:	enpp7.1 / 557756	ZFINID:	ZDB-GENE-040724-13	Length:	485	Species:	Danio rerio

Alignment Length:	439	Identity:	81/439 - (18%)
Similarity:	141/439 - (32%)	Gaps:	155/439 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQSVLADHCSAVPDLREL 75
            :||..|||.:.|.:::.:......|..:       ::|::...||.|..   .|.....|:|.::
Zfish     1 MLLALSILLLAFPASLSAPTRGHCTTGK-------NKLLLISFDGFRWD---YDRDVDTPNLDKM 55

  Fly    76 FVEQALVGISRA--CPP--TVTRPGHIAIFGG-------------FNEDPAATLTWNPSTFDSVF 123
            .|:    |:..|  .||  |:|.|.|..:..|             ||........:..:.|.:.:
Zfish    56 AVD----GVKAAYVTPPFLTITSPTHFTLLSGRYIENHGVIHNNWFNTTTQEKKQYYMTQFVNDY 116

  Fly   124 NRSRNAIGWMQAEVAKVFT---HLPTGGAPLRFETFARSDISDRL-----------RLDQ----W 170
            ..:.:...|:.|:...:.|   |.|...|..:.|.....::..|.           ::|:    |
Zfish   117 WDNGSLPIWITAQRQGLKTGSLHFPGTAAKYQNEKIKVGEVEPRFYDHTNETLWMEKVDKVMKDW 181

  Fly   171 TFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELF 235
            ..|:..:|:|                 :|..|.|...|.:.|:|...||.:....|.:....|..
Zfish   182 FKDQDLDFVT-----------------LYFGDPDSTGHKYGPDSPERREAVKKVDRTVGYIRETA 229

  Fly   236 ESVFNDSRTAYLMTADYGIS--------------------------------------------- 255
            :..........::|||:|:|
Zfish   230 KKHGLSDHLNIIITADHGMSTVFKGDQVKEIVLTDIPGFSLKDLKFHMVDYGPFGMLLPKEGMLD 294

  Fly   256 -----LHGGGGERGV----ETPFILWGAGVKRSAP-----NPG---------QNFTAGENG---- 293
                 |.||.....|    :.|..|..:...|..|     :||         || ..||:|
Zfish   295 KVYNALKGGHPHLNVYKKEDMPARLHYSKHPRLLPIILYADPGYVINGFYVFQN-NKGEHGYDNE 358

  Fly   294 --PILPLYQ--------------LEQIQLAPLMSALIGLPPPMNNMALM 326
              .:.|.::              .|.:.:.|||..|||:.|.:|:.:|:
Zfish   359 VMDMKPFFRAVGPDFHRNLLVGPFETVNVYPLMCHLIGIRPEINDGSLV 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4907	NP_651086.1	GPI_EPT_1	42..327	CDD:293744	74/408 (18%)
CG4907	NP_651086.1	PigN	413..858	CDD:282796
enpp7.1	NP_001243734.1	Enpp	29..396	CDD:293742	69/391 (18%)
enpp7.1	NP_001243734.1	Phosphodiest	31..356	CDD:279931	63/349 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900