DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4907 and ENPP2

DIOPT Version :9

Sequence 1:	NP_651086.1	Gene:	CG4907 / 42686	FlyBaseID:	FBgn0039010	Length:	919	Species:	Drosophila melanogaster
Sequence 2:	XP_006716647.1	Gene:	ENPP2 / 5168	HGNCID:	3357	Length:	940	Species:	Homo sapiens

Alignment Length:	121	Identity:	30/121 - (24%)
Similarity:	47/121 - (38%)	Gaps:	32/121 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 LEPPADRLVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRACP----------PTVTRP 95
            :.||   |::|.|||.|| |.:......:|::.:|          |:|.          ||.|.|
Human   162 VRPP---LIIFSVDGFRA-SYMKKGSKVMPNIEKL----------RSCGTHSPYMRPVYPTKTFP 212

  Fly    96 GHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPL 151
            ....:..|...:....:  ..|.:|.||:.:.:..|      .:.|.|...||.||
Human   213 NLYTLATGLYPESHGIV--GNSMYDPVFDATFHLRG------REKFNHRWWGGQPL 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4907	NP_651086.1	GPI_EPT_1	42..327	CDD:293744	30/120 (25%)
CG4907	NP_651086.1	PigN	413..858	CDD:282796
ENPP2	XP_006716647.1	SO	55..98	CDD:197571
		SO	99..142	CDD:197571
		Enpp	164..570	CDD:293742	30/119 (25%)
		Phosphodiest	166..530	CDD:279931	28/114 (25%)
		NUC	692..922	CDD:214683
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900