DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4907 and Enpp6

DIOPT Version :9

Sequence 1:	NP_651086.1	Gene:	CG4907 / 42686	FlyBaseID:	FBgn0039010	Length:	919	Species:	Drosophila melanogaster
Sequence 2:	NP_796278.1	Gene:	Enpp6 / 320981	MGIID:	2445171	Length:	440	Species:	Mus musculus

Alignment Length:	254	Identity:	52/254 - (20%)
Similarity:	92/254 - (36%)	Gaps:	67/254 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 RLVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFN---EDP 108
            :|:|.::||.|:..:..|..:::|..||:......|.......|:::.|.:..:..|.:   ...
Mouse    25 KLLVLLLDGFRSDYISEDALASLPGFREIVNRGVKVDYLTPDFPSLSYPNYYTLMTGRHCEVHQM 89

  Fly   109 AATLTWNPST---FDSVFNR-SRNAIGWMQAEV---------AKVFTHL-P------TGGAP--- 150
            .....|:|.|   ||...|| |...:.|..:|.         .||:.:. |      .|..|
Mouse    90 IGNYMWDPRTNKSFDIGVNRDSLMPLWWNGSEPLWITLMKARRKVYMYYWPGCEVEILGVRPTYC 154

  Fly   151 LRFET------FARSDISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEHV 209
            |.::|      ||.: :||.|                    ..|:...:.:..:|...||:..|.
Mouse   155 LEYKTVPTDINFANA-VSDAL--------------------DSLKSGRADLAAIYHERIDVEGHH 198

  Fly   210 HMPNSLNFREKLN------------YTQRGIRQTYELFESVFNDSRTAYLMTADYGISL 256
            :.|:|...::.|.            ...||::|  :|...:|:|.....:...|..|.|
Mouse   199 YGPSSPQRKDALRAVDTVLKYMIQWIQDRGLQQ--DLNVILFSDHGMTDIFWMDKVIEL 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4907	NP_651086.1	GPI_EPT_1	42..327	CDD:293744	52/254 (20%)
CG4907	NP_651086.1	PigN	413..858	CDD:282796
Enpp6	NP_796278.1	Phosphodiest	26..357	CDD:366747	52/253 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900