DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4907 and Enpp6

DIOPT Version :9

Sequence 1:	NP_651086.1	Gene:	CG4907 / 42686	FlyBaseID:	FBgn0039010	Length:	919	Species:	Drosophila melanogaster
Sequence 2:	XP_006253218.1	Gene:	Enpp6 / 306460	RGDID:	1311645	Length:	440	Species:	Rattus norvegicus

Alignment Length:	454	Identity:	79/454 - (17%)
Similarity:	137/454 - (30%)	Gaps:	186/454 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQSVLADH 65
            :|:.      |||.|           .|.:.|.|..|         :|:|.::||.|:..:..|.
  Rat     5 LWTF------LLLFG-----------FSWVWPASAHR---------KLLVLLLDGFRSDYISEDA 43

  Fly    66 CSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFN---EDPAATLTWNPST---FDSVFN 124
            .:::|..||:......|.......|:::.|.:..:..|.:   ........|:|.|   ||...|
  Rat    44 LASLPGFREIVNRGVKVDYLTPDFPSLSYPNYYTLMTGRHCEVHQMIGNYMWDPRTNKSFDIGVN 108

  Fly   125 R-SRNAIGWMQAE------------------------------------------------VAKV 140
            | |...:.|..:|                                                |:..
  Rat   109 RDSLMPLWWNGSEPLWITLMKARRKVYMYYWPGCEVEILGVRPTYCLEYKNVPTDINFANAVSDA 173

  Fly   141 FTHLPTGGAPLRFETFARSDI------------SDRLRLDQWTFDKVRNFMTNEQNVQPLRDATS 193
            ...|.:|.|.|......|.|:            .|.|:    ..|.|..:||.....:.|::..:
  Rat   174 LDSLKSGRADLAAIYHERIDVEGHHYGPSSPQRKDALK----AVDTVLKYMTQWIQERGLQNDLN 234

  Fly   194 VIFF-------VYLAD--IDLAEHVHMPNSLNFREKLNYTQRGIRQTY---ELFESVFNDSRTAY 246
            ||.|       ::..|  |:|::::.:.:....::     |..:...:   |....:::..||..
  Rat   235 VILFSDHGMTDIFWMDKVIELSKYISLDDLQQVKD-----QGPVVSLWPVPEKHSEIYHKLRTVE 294

  Fly   247 LMT-------------------------ADYGISL------------------------HGGGGE 262
            .||                         ||.|..:                        ||...|
  Rat   295 HMTVYEKEAIPNRFYYKKGKFVSPLTLVADEGWFIAESREALPFWMNSTGKREGWQHGWHGYDNE 359

  Fly   263 ----RGVETPFILWGAGVKRSAPNPGQNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPPMNN 322
                ||:   |:.:|       |:...||.|   .||      ..:.:..:|..::|:.|..||
  Rat   360 LMDMRGI---FLAFG-------PDFKSNFRA---API------RSVDVYNIMCNVVGITPLPNN 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4907	NP_651086.1	GPI_EPT_1	42..327	CDD:293744	70/413 (17%)
CG4907	NP_651086.1	PigN	413..858	CDD:282796
Enpp6	XP_006253218.1	Enpp	24..397	CDD:293742	67/409 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900