DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4907 and pign

DIOPT Version :9

Sequence 1:	NP_651086.1	Gene:	CG4907 / 42686	FlyBaseID:	FBgn0039010	Length:	919	Species:	Drosophila melanogaster
Sequence 2:	XP_002934435.2	Gene:	pign / 100497214	XenbaseID:	XB-GENE-960725	Length:	929	Species:	Xenopus tropicalis

Alignment Length:	969	Identity:	251/969 - (25%)
Similarity:	438/969 - (45%)	Gaps:	135/969 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQSVL---ADH 65
            :..|.|||:...||..|||.|.::..:.|..|    .|.|||.|||:||.|||||.:..   .:.
Frog     6 LAGLAVHLVFFTSIFDIYFTSPLVHGMTPHHT----SLPPPAKRLVLFVADGLRADTFFELDENE 66

  Fly    66 CSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAATLT-W--NPSTFDSVFNRSR 127
            .|..|.||.:...:...|:|....||.:||||:|:..||.||.:|... |  ||..|||:||.|:
Frog    67 TSRAPYLRNIIETRGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSIFNESK 131

  Fly   128 NAIGWMQAEV----AK------VFTHLPTGGAPLRFETFARSDISDRLRLDQWTFDKVRNFMTNE 182
            ....|...::    ||      :|||..:..:    |.||..|.:   :||.|.|:.::.|.::.
Frog   132 FTWSWGSPDILPMFAKGASGDHIFTHCYSANS----EDFASDDAT---KLDTWVFEHLKAFFSSA 189

  Fly   183 QNVQPL---RDATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVF-NDSR 243
            .:.|.|   .:...::||::|..:|...|.|.|.|..::|.:....:||::...|.|..: ||:.
Frog   190 HSNQTLLRKLNEEKIVFFLHLLGLDTNGHAHKPGSREYKENVKKVDKGIKEVALLLEDFYGNDNN 254

  Fly   244 TAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRSAPNPGQNFTAGENGPI--LPLYQLEQ 303
            |||::|:|:|::   .||.|......||.:.|||||:.......|:....:...:  |....:.|
Frog   255 TAYILTSDHGMTDWGSHGAGHPSETLTPLVAWGAGVRYPTKVQEQSDKQSKAWKLEHLKRNDVNQ 319

  Fly   304 IQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQVLHLNAMQLLAQARILIKRHEDGILYLL 368
            ..:||||::|||:|.|:|::.::|..:||.|..::.:.:..||:|:|.|.::.:.:.::..|..|
Frog   320 ADVAPLMASLIGIPYPLNSVGILPGEYLNNSELFKAESMLTNALQILEQFKVKMAQKKETTLPFL 384

  Fly   369 LPKFESLGSAEIENYPQIIKYLVAKEQYEEALKVSHKIAKLAQECMEYYHGYYHLPLLVATTASY 433
            ...|..|..::..:..:..:..:.:|.|:||:.:...:..||...:.|||.|....|.::..|.:
Frog   385 FSPFSLLSDSKQLDILRKTRSYIHRENYKEAMALCENLIDLALRGLAYYHTYDRFFLGISVFAGF 449

  Fly   434 LVWF-YLLLVRLARESNHPKSERKGYLTWTTL----MMCLGGLVLLELMILQRVPHLTAFYLLLP 493
            ..|. |::||.|...:...|...|.....|::    :..||..:::.|. .|..|.....|.|||
Frog   450 SGWISYVILVILRTNTGITKDSLKLNKEKTSVAQYAVSALGIFIIIFLK-SQSCPWTYYIYCLLP 513

  Fly   494 FGILILALAE--RPCQDRDLMCQFPVLHLVG---IVMPGV-LLILMAFHNS--HIGLLYL---PI 547
            ..:......|  ..|...|.:.....|.:||   :...|: :|:|..|:.|  .:||:..   |:
Frog   514 IPVWYAVSKEWYILCNLTDCLQSLSPLRIVGFLTVTFMGIEVLVLSFFYRSILTVGLIAFACWPV 578

  Fly   548 VCLNNRRAFFRPSLKLIFWLALVFLLS------------GILLVKQSASLHFITDTIG----VY- 595
            |...:.:|    .:..:.|:.|..||:            .|.||..:..|..:...:.    :|
Frog   579 VMQISTQA----KITTLIWVFLCLLLAVFPLMPVVGKEPNITLVTTAGLLALLISLVSCLWVIYK 639

  Fly   596 -----IGN----SHVVYFSMILSIIRPLILGHQHSTRVWIVNMAALLVTAYGIYQWDADQPVCTY 651
                 .||    .||.  .|::.|:...|:...||:          |....|:       |:...
Frog   640 RKNKSAGNIDKMVHVC--QMLILILAMYIVNTTHSS----------LAAKQGL-------PLINQ 685

  Fly   652 VYAACWSYLLFAFLSIPYSGTKDLRRRLELIIFNMLTVHIMLTTSIGSLFVQI----MVTEFVL- 711
            :.:  |:.|..| |.:|...|..|.:||..|..::::.:::|:|...:||..:    |.|...:
Frog   686 IVS--WTVLASA-LVVPLCTTAVLFQRLLSIFLSLMSTYLLLSTGYEALFPLVLSCLMCTWIYIE 747

  Fly   712 --GLELYEESFSY----ANLKDAIANQQQNNQGLEESRNESPNNPLEHVRQSYRYAALILLYLYI 770
              .|..|..||.|    .:....|...:|.|              |:.:|:|:    .::.::..
Frog   748 QGTLVKYGLSFKYMLNGIDFSPEITQSRQLN--------------LDDIRRSF----FLVFFIIT 794

  Fly   771 SFFGTGHWFFNFTFKPMTSRLFFPQFHLHMLVAFILLKIFIPSIIVMSSIYALVSFGRKNVRSIF 835
            :|||||:.....:|.|.:...|...|...::...::.||.||.::||.:...:....:.:.:.:|
Frog   795 AFFGTGNIASINSFDPASVYCFLTVFSPFVMGGLMMWKILIPFVLVMCAFETVQISAQISSKCLF 859

  Fly   836 ICLFLMNDAMSLYFCYFVINRGSLEKVRESLDRLLVSHVFIILLLVCSWIAKGFLANTK 894
            :.:.::.|.|||:|.:.|.:.||...:..|:...::.....|.|::.|.:.. :|..||
Frog   860 LIVLVITDIMSLHFFFLVKDYGSWLDIGTSISHFVIVMSTTIFLMLLSGLVH-YLTTTK 917

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4907	NP_651086.1	GPI_EPT_1	42..327	CDD:293744	101/309 (33%)
CG4907	NP_651086.1	PigN	413..858	CDD:282796	109/497 (22%)
pign	XP_002934435.2	GPI_EPT_1	40..343	CDD:293744	101/309 (33%)
pign	XP_002934435.2	PigN	429..882	CDD:398585	109/497 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D141925at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2480
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010