DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6d4 and CYP705A32

DIOPT Version :9

Sequence 1:	NP_651082.1	Gene:	Cyp6d4 / 42682	FlyBaseID:	FBgn0039006	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_188731.1	Gene:	CYP705A32 / 821645	AraportID:	AT3G20950	Length:	526	Species:	Arabidopsis thaliana

Alignment Length:	469	Identity:	105/469 - (22%)
Similarity:	195/469 - (41%)	Gaps:	82/469 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 QEKSMGLAIYDVYVKSKERV-------LGIYLLFRPAVLIRDADLARRVLAQDFASFHDRGVYVD 107
            |..::.|.:..:..||.:::       |.:.:...|.||...|.:|..:......:...|| :..
plant    55 QSNNLHLLLSALVHKSFQKISYKYGPLLHLRVFHVPIVLASSASVAYEIFKAQDVNVSSRG-HAP 118

  Fly   108 EERDPL---SANIFSLRGQSWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEE--G 167
            .....|   |:..|:..|..::.||.:::.     ||         :|.:.:...:|...:|  .
plant   119 AGESLLFGSSSFFFAPYGDYFKFMRKLIAT-----KL---------LGPQALERSRKIRADELDR 169

  Fly   168 FKEVDIKKVMQNYAIDIIASTIFGLDVNSFENPDNKFRKLV---SLARANNRFNAMFGMMIFLVP 229
            |....:.|.|:..::||:..   ...:|     :|...|::   |.:..|.....:.|::|....
plant   170 FYRNLLDKAMKKESVDIVEE---AAKLN-----NNIICKMIMGRSCSEDNGEAERVRGLVIESTA 226

  Fly   230 SIAQFLFRIGFKNP---VGLAMLQ------------IVKETVEYREKHGIVRK--DLLQLLIQLR 277
            ...|....:.|..|   :|:::.|            :.|..||:.|:.|...|  |::.||::..
plant   227 LTKQIFLGMIFDKPLKKLGISLFQKDIKSVSRFDELLEKILVEHEERMGKHYKANDMMDLLLEAY 291

  Fly   278 NTGKIDENDEKSFSIQKTPDGHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLK 342
            .    |||.|     .|....|||::.::.:        |||.:|:..|..:|:.||...|.:|:
plant   292 G----DENAE-----YKITRNHIKSLFVDLV--------IAGTDTSAQTIEWTMAELINNPNILE 339

  Fly   343 RLQDEVDETLAKNDGKITYDSLNKMEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKG 407
            ||::|: |::..|...:....|..:.:|...|:|.:|.:|...:..|...:...:  ....||:.
plant   340 RLREEI-ESVVGNTRLVQETDLPNLPYLQAVVKEGLRLHPPGAVFLRTFQERCEL--KGFYIPEK 401

  Fly   408 TPVVISLYGIHHDAEYFPDPETYDPERFSEESRN-------YNPTAFMPFGEGPRICIAQRMGRI 465
            |.:|:::|.|..|.:.:.|||.:.||||...||:       .....:|||..|.|.|....:..:
plant   402 TLLVVNVYAIMRDPKLWEDPEEFKPERFIASSRSGQEDEIREEVLKYMPFSTGRRGCPGSNLAYV 466

  Fly   466 NSKLAIIKILQNFN 479
            :...||..:.|.|:
plant   467 SVGTAIGVMAQCFD 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	p450	58..500	CDD:278495	103/461 (22%)
CYP705A32	NP_188731.1	p450	16..514	CDD:299894	105/469 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D467733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920