Protein Alignment Cyp6d4 and CYP4F11

DIOPT Version :10

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_067010.3
• Gene: CYP4F11 / 57834
• HGNCID: 13265
• Length: 524
• Species: Homo sapiens
• Alignment Length: 531
• Identity: 144/531 - (27%)
• Similarity: 233/531 - (43%)
• Gaps: 88/531 - (16%)

  Fly     4 LILLAV---TLL--TLAWFYLKRHYEYWER-RGFP-------FEKHSGIPFGCLDSVWRQEKSMG 55
            |:||.|   .||  .|||.|  ..|:...| :.||       |..|.|:       |...|:.|.
Human    20 LLLLLVGGSWLLARVLAWTY--TFYDNCRRLQCFPQPPKQNWFWGHQGL-------VTPTEEGMK 75

  Fly    56 --LAIYDVYVKSKERVLGIYLLFRPAVLIRDADLARRVLAQDFASFHDRGVYVDEERDPLSANIF 118
              ..:...|.:..:..||...   |.:::...|:.|.:.:...|......::....:..|...:.
Human    76 TLTQLVTTYPQGFKLWLGPTF---PLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLL 137

  Fly   119 SLRGQSWRSMRHMLSPCFTSGKLK---SMFSTSEDI-GDKMVAHLQKELPEEGFKEVDIKKVMQN 179
            ...|..|...|.||:|.|....||   .:|:.|.:| .||.     :.|..||...:|:.:.:..
Human   138 LSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKW-----QRLASEGSARLDMFEHISL 197

  Fly   180 YAIDIIASTIFGLDVNSFENPDNKFRKLVSLARANNRFNAMFGMMIFLVPSIAQFLFRIGFKNPV 244
            ..:|.:...:|..:.|..|.|......::.|:             .|:.....|.|....|
Human   198 MTLDSLQKCVFSFESNCQEKPSEYIAAILELS-------------AFVEKRNQQILLHTDF---- 245

  Fly   245 GLAMLQIVKETVEYREKHGIVRKDLLQLLIQLRN----TGKIDE---NDEKS--------FSIQK 294
               :..:..:...:|....:|. |....:||.|.    |..||:   |..||        ..:.|
Human   246 ---LYYLTPDGQRFRRACHLVH-DFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFIDVLLLSK 306

  Fly   295 TPDGHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDG-K 358
            ..||  |.:|.|.|.|:|..|...|.:||.|..::.:|.||::||..::.:.||.|.|...:. :
Human   307 DEDG--KELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIE 369

  Fly   359 ITYDSLNKMEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEY 423
            |.:|.|.::.||.:|::|::|.:|.:|:::|.||||:.:|| ..|||||...:|::.|||::...
Human   370 IEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPD-GRVIPKGIVCLINIIGIHYNPTV 433

  Fly   424 FPDPETYDPERFSEES-RNYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNV------- 480
            :||||.|||.||.:|: :..:|.||:||..|||.||.|.......|:.:...|.:|.:
Human   434 WPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTEP 498

  Fly   481 ----EVMSRSE 487
                |::.|:|
Human   499 RRKPELILRAE 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	CYP6-like	66..504	CDD:410679	123/454 (27%)
CYP4F11	NP_067010.3	CYP4F	74..515	CDD:410772	125/468 (27%)