Protein Alignment Cyp6d4 and cyp26c1

DIOPT Version :10

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_001025122.2
• Gene: cyp26c1 / 554036
• ZFINID: ZDB-GENE-050714-2
• Length: 554
• Species: Danio rerio
• Alignment Length: 575
• Identity: 116/575 - (20%)
• Similarity: 220/575 - (38%)
• Gaps: 176/575 - (30%)

  Fly     3 SLILLAVTLLTLAWFYLKRHYEYWE-RRGFPFEKHSGIPFGCLDSVWRQEKSMGLAIY------- 59
            :::||||:.|            .|| |.....::...:|.        .:.|||..:.
Zfish    22 TVLLLAVSRL------------LWEFRWSITRDRTCKLPL--------PQGSMGWPLVGETFHWL 66

  Fly    60 ----DVYVKSKE---RVLGIYLLFRPAVLIRDADLARRVLAQDFASFHDRGVYVDEERDPLSAN- 116
                ..::..:|   :|...:||.:|.:.:..|:..|::|..:......:  :....|..|..|
Zfish    67 FQGSSFHISRREKHGKVFKTHLLGKPLIRVTGAENIRKILLGEHTVVCTQ--WPQSTRIILGPNT 129

  Fly   117 IFSLRGQSWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEVDIKKVMQNYA 181
            :.:..|...:..|.:|:..|:.|.|::..:..:|:   :.:.:.|...|.|  .|::....::..
Zfish   130 LVNSVGDLHKRKRKVLAKVFSRGALEAYLTRLQDV---VKSEIAKWCTETG--SVEVYTAAKSLT 189

  Fly   182 IDIIASTIFGLDVNSFENPDNKFRKLVSLARA-----NNRFNAMFGMMIFLVPSIAQFLFRIGFK 241
            ..|....:.||.:..        :::..|::.     ||                   ||.:...
Zfish   190 FRIAVRVLLGLHLEE--------QQITYLSKTFEQLMNN-------------------LFSLPID 227

  Fly   242 NPV-GL------------AMLQIVKETVEYREKHGIVRKDLLQLLIQLRNTGKIDENDEKSFSIQ 293
            .|| ||            ||.:|::|.::.::     ..|.......:.::.:  |||.: .::|
Zfish   228 TPVSGLRKGIRAREILHSAMEKIIEEKLKKQQ-----ASDYCDAFDYMLSSAR--ENDYE-LTMQ 284

  Fly   294 KTPDGHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDG- 357
            :..:           ||...||  |...||.|.:...|.:|.::|::.:|.:.|::......||
Zfish   285 ELKE-----------TAVELIF--AAHSTTASASTSLIMQLLRHPDVSERARAELESEGLITDGH 336

  Fly   358 -------------------------------KITY---------------------DSLNKMEFL 370
                                           |.||                     :.|:::.:|
Zfish   337 GHCRSRCNGNAISEEGEAAEKSTSDRRSAINKATYFEAGDKEEGRRSRTHVPYLSLEKLSQLSYL 401

  Fly   371 DLCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEYFPDPETYDPERF 435
            |..|:|.:|..|  |:.....|...|.....:.||||..|:.|:...|..||.:.:||.:||:||
Zfish   402 DCVVKEVLRFLP--PVSGGYRTVLQTFELNGYQIPKGWSVMYSIRDTHETAEAYQNPELFDPDRF 464

  Fly   436 ---SEESRNYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSE 487
               .|||:: ...:::|||.|.|.||    ||   :||:| :|:...||:::.::
Zfish   465 CVGREESKS-ERFSYVPFGGGVRRCI----GR---ELALI-VLKTLAVELLATAD 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	CYP6-like	66..504	CDD:410679	104/500 (21%)
cyp26c1	NP_001025122.2	cytochrome_P450	59..537	CDD:477761	104/518 (20%)