Protein Alignment Cyp6d4 and cyp3a65

DIOPT Version :9

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_001032515.1
• Gene: cyp3a65 / 553969
• ZFINID: ZDB-GENE-050604-1
• Length: 517
• Species: Danio rerio
• Alignment Length: 547
• Identity: 167/547 - (30%)
• Similarity: 277/547 - (50%)
• Gaps: 82/547 - (14%)

  Fly     2 FSLILLAVTLLTL--AWFYLKRHYEYWERRGFPFEKHSGIPFGCLDSVWRQEKSMGLAIYDVYVK 64
            ::|:.....||.:  :|     .:.|:::.|.|..|  .|||  ..::.|.:.  |..::|:...
Zfish     8 WTLLAFLAALLVIYGSW-----PHRYFKKLGIPGPK--AIPF--FGTMLRYKD--GFHVFDMDCF 61

  Fly    65 SK-ERVLGIYLLFRPAVLIRDADLARRVLAQD-FASFHDR-----------GVYVDEERDPLSAN 116
            .| .|:.|||...:|.:.|.|..:.:.||.:: ::.|.:|           .|.:.|:.|
Zfish    62 EKYGRIWGIYDGRQPVLCIMDQTIIKTVLIKECYSLFTNRRNFRLNGALYDAVSIAEDDD----- 121

  Fly   117 IFSLRGQSWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEVDIKKVMQNYA 181
                    ||.:|.:|||.||||:||.||...:.....:|..:.| ..:.| :..|||:....|:
Zfish   122 --------WRRIRSVLSPSFTSGRLKEMFGIMKKHSHILVDSMGK-TAKRG-ESADIKEFFGAYS 176

  Fly   182 IDIIASTIFGLDVNSFENPDNKF----RKLVSLARANNRFNAMFGMMIFLVPSIAQFLFRIGFK- 241
            :|::.||.|.:|::|..||.:.|    :|::.....|..|     ::|...|.:|..|.::.|.
Zfish   177 MDVVTSTAFSVDIDSLNNPKDPFVTNIKKMLKFDLLNPLF-----LLIAFFPFMAPVLEKMDFAL 236

  Fly   242 NPVGL-----AMLQIVK---ETVEYREKHGIVRKDLLQLLIQLRNTGKIDENDEKSFSIQKTPDG 298
            .|..:     |.||.:|   :|....:.:...|.|.|||::. ..||           ::...||
Zfish   237 FPTSVTDFFYAALQKIKSDRDTKTVAKDNTKKRVDFLQLMVD-SQTG-----------VKHKSDG 289

  Fly   299 -HI-KTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKITY 361
             |. |.:|...|.:|:.||..||.||:.||.:|..|.||..||.:|:||:|:|||. .|...:.|
Zfish   290 EHTEKGLSDHEILSQSMIFIFAGYETSSSTLSFLFYNLATNPETMKKLQEEIDETF-PNQAPVDY 353

  Fly   362 DSLNKMEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEYFPD 426
            ::|..|::||..:.|::|.:|....|.|.|.:  ||.....:|||...|::..|.:|.|.:|:.:
Zfish   354 ETLMSMDYLDAALSESLRLFPVAARLERVCKK--TVEINGLLIPKDLVVMVPTYALHRDPDYWSE 416

  Fly   427 PETYDPERFSEESR-NYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSEIEF 490
            ||::.||||::.:: :.:|..:||||.|||.||..|..::..||||::|||.|:|.|...:::..
Zfish   417 PESFKPERFTKGNKESIDPYMYMPFGLGPRNCIGMRFAQVTMKLAIVEILQRFDVSVCDETQVPL 481

  Fly   491 E--NSGIALIPKHGVRVRLSKRVPKLS 515
            |  .:|: |.||..::::|..|  |||
Zfish   482 ELGFNGL-LSPKDPIKLKLQPR--KLS 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	p450	58..500	CDD:278495	147/472 (31%)
cyp3a65	NP_001032515.1	p450	35..499	CDD:278495	156/505 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	226	1.000	Domainoid score	I2453
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8426
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.920