Protein Alignment Cyp6d4 and CYP4V2

DIOPT Version :10

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_997235.3
• Gene: CYP4V2 / 285440
• HGNCID: 23198
• Length: 525
• Species: Homo sapiens
• Alignment Length: 409
• Identity: 110/409 - (26%)
• Similarity: 193/409 - (47%)
• Gaps: 30/409 - (7%)

  Fly   113 LSANIFSLRGQSWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEVDIKKVM 177
            |...:.:..|..|||.|.||:|.|....|:.......:..:.:|..|:|.:.:|.|   :....:
Human   131 LGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAF---NCFFYI 192

  Fly   178 QNYAIDIIASTIFGLDVNSFENPDNKFRKLVSLARANNRFNAMFGMMI---FLVPSIAQFLFRIG 239
            ...|:|||..|..|.::.:..|.|:::      .||..|.:.|....|   :|...:...:|:.|
Human   193 TLCALDIICETAMGKNIGAQSNDDSEY------VRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEG 251

  Fly   240 FKNPVGLAMLQ-IVKETVEYREKHGIVRKDLLQLLIQLRNTGK---IDENDEKSF--SIQKTPDG 298
            :::...|.:|. .....:..|.......:|       .|..|:   ..:|..::|  .:....|.
Human   252 WEHKKSLQILHTFTNSVIAERANEMNANED-------CRGDGRGSAPSKNKRRAFLDLLLSVTDD 309

  Fly   299 HIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKITYDS 363
            ....:|.|.|..:...|...|.:||.:...:::|.|...||:.|::..|:|:...|:|...|.:.
Human   310 EGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVED 374

  Fly   364 LNKMEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEYFPDPE 428
            |.|:.:|:..::||:|.:|.:|:..|..::|..|  ..:.:.|||..||..|.:|.|..|||:||
Human   375 LKKLRYLECVIKETLRLFPSVPLFARSVSEDCEV--AGYRVLKGTEAVIIPYALHRDPRYFPNPE 437

  Fly   429 TYDPER-FSEESRNYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEV-MSRSEIEFE 491
            .:.||| |.|.::..:|.|::||..|||.||.|:...:..|..:..||::|.:|. ..|.|:..|
Human   438 EFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLE 502

  Fly   492 NSGIALIPKHGVRVRLSKR 510
            .. :.|.|.:|:.::|.:|
Human   503 GQ-LILRPSNGIWIKLKRR 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	CYP6-like	66..504	CDD:410679	108/401 (27%)
CYP4V2	NP_997235.3	CYP4V	76..515	CDD:410773	108/402 (27%)