Protein Alignment Cyp6d4 and Cyp3a2

DIOPT Version :9

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_695224.3
• Gene: Cyp3a2 / 266682
• RGDID: 708379
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 539
• Identity: 182/539 - (33%)
• Similarity: 279/539 - (51%)
• Gaps: 87/539 - (16%)

  Fly     5 ILLAVTLLTLAWFYLKRHYEYWERRGFPFEKHSGIPFGCLDSVWRQEKSMGLAIYDVYVKSKERV 69
            :||||.|:.|......|| ..::::|.|..|  .:||  |.:|....|.:|....:.| |...::
  Rat    13 VLLAVILVLLYRLGTHRH-GIFKKQGIPGPK--PLPF--LGTVLNYYKGLGRFDMECY-KKYGKI 71

  Fly    70 LGIYLLFRPAVLIRDADLARRVLAQD-FASFHDR---------GVYVDEERDPLSANIFSLRGQS 124
            .|::....|...|.|.::.:.||.:: |:.|.:|         |..|...:|           :.
  Rat    72 WGLFDGQTPVFAIMDTEMIKNVLVKECFSVFTNRRDFGPVGIMGKAVSVAKD-----------EE 125

  Fly   125 WRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEVDIKKVMQNYAIDIIASTI 189
            |:..|.:|||.||||:||.||...|..||.:|.:|::| .|.| |.|.:|||...|::|:|.||.
  Rat   126 WKRYRALLSPTFTSGRLKEMFPIIEQYGDILVKYLKQE-AETG-KPVTMKKVFGAYSMDVITSTS 188

  Fly   190 FGLDVNSFENPDNKF-RKLVSLARANNRFNAMFGMMI---FLVP-------------SIA---QF 234
            ||::|:|..||.:.| .|...|.|. :.|:.:|..::   ||.|             |||   :|
  Rat   189 FGVNVDSLNNPKDPFVEKTKKLLRF-DFFDPLFLSVVLFPFLTPIYEMLNICMFPKDSIAFFQKF 252

  Fly   235 LFRIGFKNPVGLAMLQIVKET-VEYREKHGIVRKDLLQLLIQLRNTGKIDENDEKSFSIQKTPDG 298
            :.||              ||| ::.:.||   |.|.|||::...|..|    ||.|.
  Rat   253 VHRI--------------KETRLDSKHKH---RVDFLQLMLNAHNNSK----DEVSH-------- 288

  Fly   299 HIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKITYDS 363
              |.:|...|.||:.||..||.|||.||.:|.:|.||.:|::.|:||:|:|..| .:....|||.
  Rat   289 --KALSDVEIIAQSVIFIFAGYETTSSTLSFVLYFLATHPDIQKKLQEEIDGAL-PSKAPPTYDI 350

  Fly   364 LNKMEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEYFPDPE 428
            :.:||:||:.:.||:|.||....|.|.|.:|..:...  .||||:.|.|..|.:|||.:::|.||
  Rat   351 VMEMEYLDMVLNETLRLYPIGNRLERVCKKDIELDGL--FIPKGSVVTIPTYALHHDPQHWPKPE 413

  Fly   429 TYDPERFSEESR-NYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSEIEFEN 492
            .:.|||||:|:: :.:|..::|||.|||.||..|...:|.|||:.|:||||:.:....::|..:.
  Rat   414 EFHPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIPLKL 478

  Fly   493 SGIALI-PKHGVRVRLSKR 510
            |..|:: |:..:.:::..|
  Rat   479 SRQAILEPEKPIVLKVLPR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	p450	58..500	CDD:278495	163/474 (34%)
Cyp3a2	NP_695224.3	CYP3A	67..493	CDD:410743	162/473 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	256	1.000	Domainoid score	I1960
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2893
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.970