Protein Alignment Cyp6d4 and Cyp3a23-3a1

DIOPT Version :9

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 530
• Identity: 176/530 - (33%)
• Similarity: 279/530 - (52%)
• Gaps: 96/530 - (18%)

  Fly     5 ILLAVTLLTLAWFYLKRHYEYWERRGFPFEKHSGIP-FGCLDSVWRQEKSMGLAIYDVYVKSK-E 67
            :||||.|:.|..|..:.| ..::::|.|..|  .:| ||.:.:.:     |||..:||....| .
  Rat    13 VLLAVVLVLLYGFGTRTH-GLFKKQGIPGPK--PLPFFGTVLNYY-----MGLWKFDVECHKKYG 69

  Fly    68 RVLGIYLLFRPAVLIRDADLARRVLAQD-FASFHDR---------GVYVDEERDPLSANIFSLRG 122
            ::.|::....|...|.|.::.:.||.:: |:.|.:|         |..:...:|
  Rat    70 KIWGLFDGQMPLFAITDTEMIKNVLVKECFSVFTNRRDFGPVGIMGKAISVSKD----------- 123

  Fly   123 QSWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEVDIKKVMQNYAIDIIAS 187
            :.|:..|.:|||.||||:||.||...|..||.:|.:|::   |:| |.|.:|:|...|::|:|.|
  Rat   124 EEWKRYRALLSPTFTSGRLKEMFPVIEQYGDILVKYLRQ---EKG-KPVPVKEVFGAYSMDVITS 184

  Fly   188 TIFGLDVNSFENPDNKF----RKLVSLARANNRFNAMFGMMIFLVPSIAQFLFRIGFKNPVGLAM 248
            |.||::|:|..||.:.|    :||:.:    :.|:.:| :.:.|.|          |..|| ..|
  Rat   185 TSFGVNVDSLNNPKDPFVEKAKKLLRI----DFFDPLF-LSVVLFP----------FLTPV-YEM 233

  Fly   249 LQIV---KETVE------YR---------EKHGIVRKDLLQLLIQLRNTGKIDENDEKSFSIQKT 295
            |.|.   |:::|      ||         :||   |.|.|||::...|    |..|::|
  Rat   234 LNICMFPKDSIEFFKKFVYRMKETRLDSVQKH---RVDFLQLMMNAHN----DSKDKES------ 285

  Fly   296 PDGHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKIT 360
               |.....:| ||||:.||..||.|.|.||.:|.::.||.:|:..|:||:|:|..| .|....|
  Rat   286 ---HTALSDME-ITAQSIIFIFAGYEPTSSTLSFVLHSLATHPDTQKKLQEEIDRAL-PNKAPPT 345

  Fly   361 YDSLNKMEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHV-IPKGTPVVISLYGIHHDAEYF 424
            ||::.:||:||:.:.||:|.||....|.|.|.:|..:   |.| :|||:.|:|..|.:|.|.:::
  Rat   346 YDTVMEMEYLDMVLNETLRLYPIGNRLERVCKKDVEI---NGVFMPKGSVVMIPSYALHRDPQHW 407

  Fly   425 PDPETYDPERFSEESR-NYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSEI 488
            |:||.:.|||||:|:: :.:|..::|||.|||.||..|...:|.|||:.|:||||:.:....::|
  Rat   408 PEPEEFRPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQI 472

  Fly   489 EFENSGIALI 498
            ..:.|...|:
  Rat   473 PLKLSRQGLL 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	p450	58..500	CDD:278495	159/476 (33%)
Cyp3a23-3a1	NP_037237.2	p450	39..492	CDD:278495	167/503 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	256	1.000	Domainoid score	I1960
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2893
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.970