Protein Alignment Cyp6d4 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_036819.1
• Gene: Tbxas1 / 24886
• RGDID: 3826
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 156/554 - (28%)
• Similarity: 265/554 - (47%)
• Gaps: 86/554 - (15%)

  Fly     5 ILLAVTLLTLAWFYLKRHYEYWERRGFPFEKHSGIPFGCLDSVWRQEKSMGLAIYDVYVKSKER- 68
            :.|:|.||.|..:|....:....:.|....:.|  ||......:||      ..::.:::.:||
  Rat    18 VTLSVVLLALLKWYSTSAFSRLRKLGIRHPEPS--PFVGNLMFFRQ------GFWESHLELRERY 74

  Fly    69 --VLGIYLLFRPAVLIRDADLARRVLAQDFASFHDR---GVYVDEERDPLSANIFSLRGQSWRSM 128
              :.|.||..|..::|.|.|:.:.||.::|::|.:|   |:    |...::.::..||.:.|..:
  Rat    75 GPLCGYYLGRRMYIVISDPDMIKEVLVENFSNFSNRMASGL----EPKLIADSVLMLRDRRWEEV 135

  Fly   129 RHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPE-EGFKEVDIKKVMQNYAIDIIASTIFGL 192
            |..|...|:..||..|........:.:::||:..... :.|   ||::....:..:::||..||:
  Rat   136 RGALMSAFSPEKLNEMTPLISQACELLLSHLKHSAASGDAF---DIQRCYCCFTTNVVASVAFGI 197

  Fly   193 DVNSFENPDNKF-------------RKLVSLARANNRFNAMFGMMIFLVPSIAQFLFRI------ 238
            :|||.:.|::.|             |.|::|              |...|||...|.||
  Rat   198 EVNSQDAPEDPFVQHCQRVFAFSTPRPLLAL--------------ILSFPSIMVPLARILPNKNR 248

  Fly   239 ----GFKNPVGLAMLQI-VKETVEYREKHGIVRKDLLQLLIQLRNTGK---IDENDEKSFSIQKT 295
                ||.|.:...::.: .|:|.|.|      |.|.||:::..:.:..   ::..|..:.::...
  Rat   249 DELNGFFNTLIRNVIALRDKQTAEER------RGDFLQMVLDAQRSMSSVGVEAFDMVTEALSSA 307

  Fly   296 -----------PDGHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVD 349
                       |....|.::::.|..|||:|.|||.|.|.:|.:|..|.||.:||..:||..|||
  Rat   308 ECMGDPPQRCHPTSTAKPLTVDEIAGQAFLFLIAGHEITTNTLSFITYLLATHPECQERLLKEVD 372

  Fly   350 ETLAKNDGKITYDSLNK-MEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVIS 413
            ..:.|:... .|.:|.: :.:||:.|.||:|.||......||..||..|  ....||.|:.:.|:
  Rat   373 LFMEKHPAP-EYCNLQEGLPYLDMVVAETLRMYPPAFRFTREAAQDCEV--LGQHIPAGSVLEIA 434

  Fly   414 LYGIHHDAEYFPDPETYDPERFSEESR-NYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQN 477
            :..:|||.|::|:|||:|||||:.|:| ...|..::|||.|||.|:..|:|.:..||.::::|..
  Rat   435 VGALHHDPEHWPNPETFDPERFTAEARLQQKPFTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLHK 499

  Fly   478 FNVEVMSRSEIEFE-NSGIALIPKHGVRVRLSKR 510
            |..|....:::..: .|..||.||:||.|::..|
  Rat   500 FRFEACPETQVPLQLESKSALCPKNGVYVKIVSR 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	CYP6-like	66..504	CDD:410679	141/485 (29%)
Tbxas1	NP_036819.1	cytochrome_P450	74..527	CDD:477761	139/482 (29%)