Protein Alignment Cyp6d4 and Cyp26b1

DIOPT Version :10

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_780684.1
• Gene: Cyp26b1 / 232174
• MGIID: 2176159
• Length: 512
• Species: Mus musculus
• Alignment Length: 547
• Identity: 120/547 - (21%)
• Similarity: 212/547 - (38%)
• Gaps: 140/547 - (25%)

  Fly     6 LLAVTLLTLAWFYLKRHYEYWERR---------GFPFEKHS-GIPFGCLDSVW----------RQ 50
            |::||||      |....:.|:.|         ..|..|.| |.|.......|          |:
Mouse    19 LVSVTLL------LAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIGETGHWLLQGSGFQSSRR 77

  Fly    51 EKSMGLAIYDVYVKSKERVLGIYLLFRPAVLIRDADLARRVLAQDFASFHDRGVYVDEERDPLSA 115
            ||      |.       .|...:||.||.:.:..|:..|::|..:
Mouse    78 EK------YG-------NVFKTHLLGRPLIRVTGAENVRKILLGE-------------------- 109

  Fly   116 NIFSLRGQSW-RSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAH--LQKELPEEGFKEVDIKKVM 177
              ..|....| ||.|.:|.|...:..:..:......:..|:.:|  |:..||:       |:.|:
Mouse   110 --HQLVSTEWPRSARVLLGPNTVANSIGDIHRNKRKVFSKIFSHEALESYLPK-------IQLVI 165

  Fly   178 QN---------YAIDIIAST---IFGLDVN---SFENPDNKFRKLVSLARANNRFNAMFGMMIFL 227
            |:         .||::....   .|.:.|.   .|..|:.....|..:.:       .|...:|.
Mouse   166 QDTLRAWSSQPEAINVYQEAQRLTFRMAVRVLLGFSIPEEDLGHLFEVYQ-------QFVENVFS 223

  Fly   228 VPSIAQFLFRIGFKNPVGLAMLQIVKETVE--YREK----HGIVRKDLLQLLIQLRNTGKIDEND 286
            :|....|   .|::.  |:...||:::.:|  .|||    .|....|.|.:||:      ..:..
Mouse   224 LPVDLPF---SGYRR--GIQARQILQKGLEKAIREKLQCTQGKDYSDALDILIE------SSKEH 277

  Fly   287 EKSFSIQKTPDGHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEV-DE 350
            .|..::|:..||.::.|             .|...||.|.:...|.:|.::|.:|::|::|: .:
Mouse   278 GKEMTMQELKDGTLELI-------------FAAYATTASASTSLIMQLLKHPAVLEKLREELRAQ 329

  Fly   351 TLAKN-----DGKITYDSLNKMEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPV 410
            .|...     :|.:..|:|:.:.:||..::|.:|.:  .|:.....|...|.......||||..|
Mouse   330 GLLHGGGCPCEGTLRLDTLSSLRYLDCVIKEVMRLF--TPVSGGYRTVLQTFELDGFQIPKGWSV 392

  Fly   411 VISLYGIHHDAEYFPDPETYDPERFSEESRNYNPTA---FMPFGEGPRICIAQRMGRINSKLAII 472
            :.|:...|..|..|.|...:||:||| ::|:.:...   ::|||.|.|.|:.:.:.::..|:..:
Mouse   393 MYSIRDTHDTAPVFKDVNVFDPDRFS-QARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAV 456

  Fly   473 KILQNFNVEVMSRSEIEFENSGIALIP 499
            ::......|:.:|:   |..  |.|:|
Mouse   457 ELASTSRFELATRT---FPR--ITLVP 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	CYP6-like	66..504	CDD:410679	102/467 (22%)
Cyp26b1	NP_780684.1	CYP26B1	60..490	CDD:410730	107/500 (21%)