DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cyp6d4 and Tbxas1

DIOPT Version :9

Sequence 1:NP_651082.1 Gene:Cyp6d4 / 42682 FlyBaseID:FBgn0039006 Length:515 Species:Drosophila melanogaster
Sequence 2:NP_035669.3 Gene:Tbxas1 / 21391 MGIID:98497 Length:533 Species:Mus musculus


Alignment Length:544 Identity:158/544 - (29%)
Similarity:266/544 - (48%) Gaps:66/544 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 ILLAVTLLTLAWFYLKRHYEYWERRGFPFEKHSGIPFGCLDSVWRQEKSMGLAIYDVYVKSKER- 68
            :.|.|.||.|..:|....:...|:.|....|.|  ||......:||      ..::..::.:|| 
Mouse    18 VTLLVALLALLKWYSMSAFSRLEKLGIRHPKPS--PFVGNLMFFRQ------GFWESQLELRERY 74

  Fly    69 --VLGIYLLFRPAVLIRDADLARRVLAQDFASFHDR---GVYVDEERDPLSANIFSLRGQSWRSM 128
              :.|.||..|..|:|.:.|:.::||.::|::|.:|   |:    |...::.::..||.:.|..:
Mouse    75 GPLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNRMASGL----EPKMVADSVLLLRDRRWEEV 135

  Fly   129 RHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQK-ELPEEGFKEVDIKKVMQNYAIDIIASTIFGL 192
            |..|...|:..||..|........:.:||||:: ....:.|   :|::....|.||::||..||.
Mouse   136 RGALMSSFSPEKLDEMTPLISQACELLVAHLKRYAASRDAF---NIQRCYCCYTIDVVASVAFGT 197

  Fly   193 DVNSFENPDNKFRKLVSLARANNRFNAMFGMMIFLV--PSIAQFLFRI----------GFKNPVG 245
            .|:|..:|::.|   |...|..:.|.....:::.::  |||...|.||          ||.|   
Mouse   198 QVDSQNSPEDPF---VQHCRRASTFCIPRPLLVLILSFPSIMVPLARILPNKNRDELNGFFN--- 256

  Fly   246 LAMLQIVKETVEYREKHGIV--RKDLLQLLIQLR---NTGKIDENDEKSFSIQKT---------- 295
                .:::..:..|::....  |:|.||:::..:   |:..::..|....|:..:          
Mouse   257 ----TLIRNVIALRDQQAAEERRRDFLQMVLDAQHSMNSVGVEGFDMVPESLSSSECTKEPPQRC 317

  Fly   296 -PDGHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKI 359
             |....|..:::.|..|||:|.|||.|...:|.:|..|.||.:|:..:||..|||..:.|:... 
Mouse   318 HPTSTSKPFTVDEIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQERLLKEVDLFMGKHPAP- 381

  Fly   360 TYDSLNK-MEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEY 423
            .|.||.: :.:||:.:.||:|.||......||..||..|  ....||.||.:.|::..:|||.|:
Mouse   382 EYHSLQEGLPYLDMVISETLRMYPPAFRFTREAAQDCEV--LGQRIPAGTVLEIAVGALHHDPEH 444

  Fly   424 FPDPETYDPERFSEESR-NYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSE 487
            :|:|||:|||||:.|:| ...|..::|||.|||.|:..|:|.:..||.|:::|..|..|....::
Mouse   445 WPNPETFDPERFTAEARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRFEASPETQ 509

  Fly   488 IEFE-NSGIALIPKHGVRVRLSKR 510
            :..: .|..||.||:||.:::..|
Mouse   510 VPLQLESKSALGPKNGVYIKIVSR 533

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cyp6d4NP_651082.1 p450 58..500 CDD:278495 139/479 (29%)
Tbxas1NP_035669.3 p450 47..528 CDD:365848 149/508 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0158
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D264519at33208
OrthoFinder 1 1.000 - - FOG0000037
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X40
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
65.820

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