Protein Alignment Cyp6d4 and cyp-13A4

DIOPT Version :10

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_496111.1
• Gene: cyp-13A4 / 188355
• WormBaseID: WBGene00011671
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 551
• Identity: 140/551 - (25%)
• Similarity: 251/551 - (45%)
• Gaps: 80/551 - (14%)

  Fly     3 SLILLAVTLLTLAWFYLKRHYEYWER------RGFPFEKHSGIPFGCLDSVWRQEKSMGLAIYDV 61
            ||::.....:....:|: ..:.:|.|      |||||       ||.: ..:...::.||.....
 Worm     4 SLLIAGALFIGFLTYYI-WIWSFWIRKGVKGPRGFPF-------FGVI-LKFHDYENPGLLKLGE 59

  Fly    62 YVKSKERVLGIYLLFRPAVLIRDADLARRVLAQDFASFHDRGVYVDEERDPLS--------ANIF 118
            :.|....:.||.......:::.:.:....|..:.|.:|:.|      :.:|:.        |::.
 Worm    60 WTKKYGSIYGITEGVEKTLVVSNPEFVHEVFVKQFDNFYGR------KTNPIQGDPNKNKRAHLV 118

  Fly   119 SLRGQSWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEVDIKKVMQNYAID 183
            ..:|..|:.:|.:.||.|::..|:.:.||.|:...:::.||. |...:| |.||:....|.:.:|
 Worm   119 LAQGHRWKRLRTLASPTFSNKSLRKIMSTVEETVVELMRHLD-EASAKG-KAVDLLDYYQEFTLD 181

  Fly   184 IIASTIFG-LDVNSFENPDNKFRKLVSLARANNRFNAMFGMMIFLVPS---IAQFLFR------- 237
            ||.....| .:...|.||        .|.:....|. ..|.|.||:..   ||..|.|
 Worm   182 IIGRIAMGQTESLMFRNP--------MLPKVKEIFK-KGGKMPFLIAGVFPIAGTLMRQLFMKFP 237

  Fly   238 -----IGFKNPVGLAMLQIVKETVEYR---EKHGI----VRKDLLQLLIQLR-NTGKIDENDEKS 289
                 .|..|    .|.:.:.:.:|.|   :|.||    ..:|.:.|.:..| |...|:|.....
 Worm   238 KFSPAFGIMN----TMEKALNKRLEQRAADKKAGIEPSGEPQDFIDLFLDARANVDFIEEESTLG 298

  Fly   290 FSIQKT--PDGHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETL 352
            |:..:.  .|.|   ::.:.|..|.|:|.:||.:||..:.:::.|.||.:||:.|:||:|||...
 Worm   299 FAKSEVLKVDKH---LTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQEEVDREC 360

  Fly   353 AKNDGKITYDSLNKMEFLDLCVQETIRKYPGLPIL-NRECTQDYTVPDTNHVIPKGTPVVISLYG 416
            .  |.::|:|.::|:::::..|:|.:|.||...:: ||:|.:...|....  |.:||.|.:..:.
 Worm   361 P--DPEVTFDQISKLKYMECVVKEALRMYPLASLVHNRKCMKKTNVLGVE--IDEGTNVQVDTWT 421

  Fly   417 IHHDAEYF-PDPETYDPERF-SEESRNYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFN 479
            :|:|.:.: .|...:.|||: :.:...|....::|||.||||||..|:..:..||.:..||:.:.
 Worm   422 LHYDPKVWGDDASEFKPERWETGDELFYAKGGYLPFGMGPRICIGMRLAMMEEKLLLTHILKKYT 486

  Fly   480 VEVMSRSEIEFENSGIALIPKHGVRVRLSKR 510
            .:..:.:||..:..|.|.|....|.::|:.|
 Worm   487 FDTSTETEIPLKLVGSATIAPRNVMLKLTPR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	CYP6-like	66..504	CDD:410679	122/474 (26%)
cyp-13A4	NP_496111.1	CYP3A-like	63..511	CDD:410678	122/475 (26%)