Protein Alignment Cyp6d4 and cyp-25A1

DIOPT Version :10

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 546
• Identity: 136/546 - (24%)
• Similarity: 253/546 - (46%)
• Gaps: 84/546 - (15%)

  Fly     3 SLILLAVTLLTLAWFYLKRHYEYWERR-GFPFEKHSGIP-------FGCLDSVWRQEKSMGL--- 56
            :|::|:..::::..|::   |....|| .|...:..|:.       .|.|.....:::.:|.
 Worm     2 ALLILSSLVISIFTFFI---YIILARRERFKLREKIGLSGPEPHWFLGNLKQTAERKEKLGYDDA 63

  Fly    57 -----AIYDVYVKSKERVLGIYLLFRPAVLIRDADLARRVLAQDFASFHDRGVYVDEERDPLSAN 116
                 .:::.|.::    .|||...:..::|.:....:.|..::|::|.||.|....|.:.|:|:
 Worm    64 NRWFNELHEQYGET----FGIYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIYEANQLTAS 124

  Fly   117 -IFSLRGQSWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQ--KELPEEGFKEVDIKKVMQ 178
             :.:.....|:..|..::|.|::||:|:|   .|.|..|:...|.  :|....| ::.||....|
 Worm   125 LLMNSYSSGWKHTRSAIAPIFSTGKMKAM---QETINSKVDLFLDILREKASSG-QKWDIYDDFQ 185

  Fly   179 NYAIDIIASTIFGLDVNSFENPDNKF----RKLVSLARANNRFNAMFGMMIFLVPSIAQFLFRIG 239
            ...:|:|....|.:|.|...:.::.|    :|.:|  ..:.|.:.:....: |:|.::.|...:.
 Worm   186 GLTLDVIGKCAFAIDSNCQRDRNDVFYVNAKKYIS--NIDIRHSKIIAASV-LLPELSTFWKALY 247

  Fly   240 FKNPVGLAMLQIVKETVEYREK----HGIVRKDLLQLLIQLRNTGKIDENDEKSFSIQKTPDGHI 300
            ...|:..|.:.:|:......|:    .|....|||:||        ::..|:||
 Worm   248 KYTPLADAEIPLVEGLSNVYERRRGGEGSDSVDLLKLL--------LNREDDKS----------- 293

  Fly   301 KTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKITYDSLN 365
            |.::.:.:....|.|.:||.|||.:...:..|.|::||.:.::|.:|:.|  ||.:|.:||||::
 Worm   294 KPMTKQEVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIME--AKENGGLTYDSIH 356

  Fly   366 KMEFLDLCVQETIRKYPGLPILN---RECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEYFPDP 427
            .|::||...:||:|.||  |:::   |.|.:|.|:  .....|||..||...:.:|.:.|.:..|
 Worm   357 NMKYLDCVYKETLRFYP--PVIHFIRRLCREDITI--RGQFYPKGAIVVCLPHTVHRNPENWDSP 417

  Fly   428 ETYDPERFSEESRNYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSEIEFEN 492
            |.:.||||.......:...::|||.|||.|:..|...:..|..|:|:|..|.::       :||.
 Worm   418 EEFHPERFENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELK-------QFEG 475

  Fly   493 --------SGIALIPKHGVRVRLSKR 510
                    :|:.:.|...||:.|..|
 Worm   476 EADLIPDCNGVIMRPNDPVRLHLKPR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	CYP6-like	66..504	CDD:410679	120/459 (26%)
cyp-25A1	NP_497775.3	CYP3A-like	73..495	CDD:410678	121/464 (26%)