DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6d4 and cest-32

DIOPT Version :9

Sequence 1:	NP_651082.1	Gene:	Cyp6d4 / 42682	FlyBaseID:	FBgn0039006	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_504397.1	Gene:	cest-32 / 178909	WormBaseID:	WBGene00016862	Length:	545	Species:	Caenorhabditis elegans

Alignment Length:	369	Identity:	69/369 - (18%)
Similarity:	113/369 - (30%)	Gaps:	130/369 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 GLAIYDVYVKSKERVLGIYLLFRPAVLIRDADLARRVLAQDFASFHDRGVYVDEERDPLSANIFS 119
            |.|..:..:::||               ::|::.|     :||..|.   |..|:.:.|
Worm   236 GSAFCEFSIRTKE---------------QEAEIFR-----NFAKHHG---YEGEDSESL------ 271

  Fly   120 LRGQSWRSMRHM--LSPCFTSGKLKSMFST-----SEDIGDKMVAHLQKELPE----------EG 167
               ..|...:.:  .....|..|..|.|.|     ..|...|....|.:|.|:          ||
Worm   272 ---LEWYKSQPLSKFQETATFEKKASGFLTFIPNFDGDFFPKPFDELSREAPKLDAMATVDEYEG 333

  Fly   168 FKEVDIKKVMQNYAIDIIASTIFGLDVNSFENPDNKFRKLVSLARANNRFNAMFGMMIFLVPSIA 232
            ...:.:.:..:| .:|||.|: ||.||  .||..:..::::.....|...|....:...|:..|:
Worm   334 LGFLTMFQSRRN-DMDIIKSS-FGSDV--VENAVDVQKRIMEFYMKNIDKNDDKAVEKRLIQLIS 394

  Fly   233 QFLFRIGFKNPVGLAMLQIVKETVEY---------------------------REKHGIVRKDLL 270
            ...|.||        .|:.||.:.:|                           ...||...|.:|
Worm   395 DSWFNIG--------ALETVKTSTKYGSNAYLGSFDYYNMGSNDPYATWFPFKAANHGSELKYML 451

  Fly   271 QLLIQLRNTGKIDENDEKSFSIQKTPDGHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELA 335
            .     ...||....:|:           .|.|.:.......|:.|.......|
Worm   452 G-----EGMGKFSPIEEE-----------FKVIDMMGTLTANFVKYGNPNGING----------- 489

  Fly   336 QYPELLKRLQDEVDETLAK------------NDGKI-TYDSLNK 366
              |||.|:...|...:..|            .||:: .::.:||
Worm   490 --PELWKKYTPEKPYSYFKIDYPKSEMRDNFQDGRLKLFEDINK 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	p450	58..500	CDD:278495	67/366 (18%)
cest-32	NP_504397.1	COesterase	15..516	CDD:278561	65/352 (18%)
cest-32	NP_504397.1	Aes	<104..>227	CDD:223730
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010