Protein Alignment Cyp6d4 and cyp-25A2

DIOPT Version :10

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_497776.2
• Gene: cyp-25A2 / 175495
• WormBaseID: WBGene00007964
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 533
• Identity: 139/533 - (26%)
• Similarity: 255/533 - (47%)
• Gaps: 64/533 - (12%)

  Fly     3 SLILLAVTLLTLAWFYLKRHYEYWERRGF--PFEKHSGIPFGCLDSVWRQEKSMGLAIYD----- 60
            |:::|.|:.:....|..:..::..|:.|.  | |.|..:  |.|..:..:::.:|   ||
 Worm     8 SILILLVSFIIYILFARREQFKLREKIGLTGP-EPHWFM--GNLKQIVDRKEKLG---YDDSNKW 66

  Fly    61 --VYVKSKERVLGIYLLFRPAVLIRDADLARRVLAQDFASFHDRGVYVDEERDPLSANIF-SLRG 122
              ...|......|||...:..:::.:.:..:.|..::|::|.||.|....:.:.|:.::. :...
 Worm    67 FNELHKQYGETFGIYFGAQMNIVLSNEEDIKEVFIKNFSNFSDRIVPPIFDSNQLNQSLLQNTYA 131

  Fly   123 QSWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQ--KELPEEGFKEVDIKKVMQNYAIDII 185
            ..|:..|..::|.|::||:|:|   .|.|..|:...|.  :|....| ::.||.:..|...:|:|
 Worm   132 TGWKHTRSAIAPIFSTGKMKAM---QETIHSKVDLFLDILREKASSG-QKWDIYEDFQGLTLDVI 192

  Fly   186 ASTIFGLDVNSFENPDNKF----RKLVSLARANNRFNAMFGMMIFLVPSIAQFLFRIGFK-NPVG 245
            ....|.:|.|...:.::.|    ||.:  |..:.|.:.:.... |::|.:|. |:|..:| .|:.
 Worm   193 GKCAFAIDSNCQRDRNDVFYVNARKFI--ANIDIRHSKVIAAS-FILPELAP-LWRALYKYTPLA 253

  Fly   246 LAMLQIVKETVEYREK----HGIVRKDLLQLLIQLRNTGKIDENDEKSFSIQKTPDGHIKTISLE 306
            .|.:.:|:......|:    .|....|||:||        ::..|:||           |.::.:
 Worm   254 DAEIPLVEGLSNVYERRRGGEGSDSVDLLKLL--------LNREDDKS-----------KPMTKQ 299

  Fly   307 AITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKITYDSLNKMEFLD 371
            .:....|.|.:||.|||.:...:..|.|::||.:.::|.:|:.|  ||.:|.:||||::.|::||
 Worm   300 EVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIME--AKENGGLTYDSIHNMKYLD 362

  Fly   372 LCVQETIRKYPGLPI---LNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEYFPDPETYDPE 433
            ...:||:|.||  |:   :||.|..|.|:  .....|||:.|....:.:|.:.|.:..||.:.||
 Worm   363 YVYKETLRCYP--PVIHFINRRCLADITI--RGQFYPKGSVVTCLPHTVHLNPENWDSPEEFHPE 423

  Fly   434 RFSEESRNYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNV-EVMSRSEIEFENSGIAL 497
            ||.......:...::|||.|||.|:..|...:..|..|:|:|..|.: :....:::..:.:|:.:
 Worm   424 RFENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELKQFKGEADLIPDCNGVIM 488

  Fly   498 IPKHGVRVRLSKR 510
            .||..||:.|..|
 Worm   489 RPKDPVRLLLKPR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	CYP6-like	66..504	CDD:410679	120/453 (26%)
cyp-25A2	NP_497776.2	CYP3A-like	73..495	CDD:410678	120/454 (26%)