Protein Alignment Cyp6d4 and CYP4B1

DIOPT Version :10

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_001093242.1
• Gene: CYP4B1 / 1580
• HGNCID: 2644
• Length: 512
• Species: Homo sapiens
• Alignment Length: 471
• Identity: 118/471 - (25%)
• Similarity: 196/471 - (41%)
• Gaps: 96/471 - (20%)

  Fly    82 IRDADLARRVLAQDFASFHDRGVYVDEERDPLSANIFS------------LRGQSWRSMRHMLSP 134
            |.:.|.|:.|        :.||       ||.:.:::.            |.|..|...|.:|:|
Human    94 IYEPDYAKAV--------YSRG-------DPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTP 143

  Fly   135 CFTSGKLK---SMFSTSEDIG-DKMVAHLQKELPEEGFKEVDIKKVMQNYAIDIIASTIFGL-DV 194
            .|....||   ::|:.|..|. ||.     :|...|| |..||...:.:.|::.:....||. |.
Human   144 GFHYDVLKPYVAVFTESTRIMLDKW-----EEKAREG-KSFDIFCDVGHMALNTLMKCTFGRGDT 202

  Fly   195 NSFENPDNKF------------RKLVSLARANNRFNAMFGMMIFLVPSIAQFLFRIGFKNPVGLA 247
            ....:.|:.:            ::|||....|:       .:.:|.|...:|           |.
Human   203 GLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHND-------FIYWLTPHGRRF-----------LR 249

  Fly   248 MLQIVKETVE--YREKHGIVRKDLLQLLIQLRN--------TGKIDENDEKSFSIQKTPDGHIKT 302
            ..|:..:..:  .||:...::.:.::..||.|.        .|..||:|.|
Human   250 ACQVAHDHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIK-------------- 300

  Fly   303 ISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKITYDSLNKM 367
            :|...:.|:...|...|.:||.|..::.:|.:|.|||...|.::||.|.|...| ...:|.|.||
Human   301 LSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKM 364

  Fly   368 EFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEYFPDPETYDP 432
            .:|.:|::|:.|.||.:|.:.|:.::..|..| ...:|.|:.:.:.:|.:|.::..:||||.:|.
Human   365 TYLTMCIKESFRLYPPVPQVYRQLSKPVTFVD-GRSLPAGSLISMHIYALHRNSAVWPDPEVFDS 428

  Fly   433 ERFS-EESRNYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSEIEFENSGIA 496
            .||| |.:...:|.|||||..|||.||.|:......|:.....|..|... :..|.:..:...:.
Human   429 LRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFS-LDPSRLPIKMPQLV 492

  Fly   497 LIPKHGVRVRLSKRVP 512
            |..|:|..:.|....|
Human   493 LRSKNGFHLHLKPLGP 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	CYP6-like	66..504	CDD:410679	116/461 (25%)
CYP4B1	NP_001093242.1	CYP4B-like	67..502	CDD:410771	116/463 (25%)