Protein Alignment Cyp6d4 and Cyp26a1

DIOPT Version :10

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_569092.2
• Gene: Cyp26a1 / 154985
• RGDID: 620161
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 515
• Identity: 115/515 - (22%)
• Similarity: 210/515 - (40%)
• Gaps: 147/515 - (28%)

  Fly    30 GFPFEKHSGIPFG-CLDSVWRQEKSMGLAIYDVYVKSKERVLGI----YLLFRPAVLIRDADLAR 89
            ||||       || .|..|.::.|         :::.|.|..|.    :|..||.|.:..||..|
  Rat    50 GFPF-------FGETLQMVLQRRK---------FLQMKRRKYGFIYKTHLFGRPTVRVMGADNVR 98

  Fly    90 RVLAQDFASFHDRGVYVDEERDPLSANIFSLRGQSW-RSMRHMLSPCFTSGKLKSMFSTSEDIGD 153
            |:|             :.|.|         |....| .|:|.:|.    :|.|.::..:|
  Rat    99 RIL-------------LGEHR---------LVSVHWPASVRTILG----AGCLSNLHDSS----- 132

  Fly   154 KMVAHLQ-KELPEEGFKEVDIKKVMQNYAIDIIASTIFGLDVNSFENPDNKFRKLVSLARANNRF 217
                |.| |::..:.|.    ::.:|.| :.:||..:.|.              |........|
  Rat   133 ----HKQRKKVIMQAFN----REALQCY-VPVIAEEVSGC--------------LEQWLSCGER- 173

  Fly   218 NAMFGMMIFLVPSIAQFLFRIGFK-------NPVGLAMLQIVKETVEYREKHGIVRKDLLQLLIQ 275
                |::::  |.:.:.:|||..:       .|.|..  :..::.||..|:   :.::|..|.|.
  Rat   174 ----GLLVY--PEVKRLMFRIAMRILLGCEPGPAGGG--EDEQQLVEAFEE---MTRNLFSLPID 227

  Fly   276 LRNTG-------------KIDEN-DEKSFSIQKT-PDGHIK---------------TISLEAITA 310
            :..:|             :|:|| ..|...:|.. ||...|               .:.::|:..
  Rat   228 VPFSGLYRGVKARNLIHARIEENIRAKIRRLQAAEPDAGCKDALQLLIEHSWERGERLDMQALKQ 292

  Fly   311 QAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDE--TLAK--NDGKITYDSLNKMEFLD 371
            .:......|.|||.|.|...|..|..||.:|:::::|:..  .|.|  ::.|:..::|.:::::.
  Rat   293 SSTELLFGGHETTASAATSLITYLGLYPHVLQKVREEIKSKGLLCKSHHEDKLDMETLEQLKYIG 357

  Fly   372 LCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEYFPDPETYDPERFS 436
            ..::||:|..|.:|...|...:.:.:  ..:.||||..|:.|:...|..|:.|.:.|.::|:||:
  Rat   358 CVIKETLRLNPPVPGGFRVALKTFEL--NGYQIPKGWNVIYSICDTHDVADSFTNKEEFNPDRFT 420

  Fly   437 ----EESRNYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSEIEFEN 492
                |::..:   :|:|||.|.|.|:.:...:|        :|:.|.||:..|.:.:..|
  Rat   421 SLHPEDTSRF---SFIPFGGGLRSCVGKEFAKI--------LLKIFTVELARRCDWQLLN 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	CYP6-like	66..504	CDD:410679	106/478 (22%)
Cyp26a1	NP_569092.2	cytochrome_P450	55..490	CDD:477761	110/503 (22%)