Protein Alignment Cyp6d4 and Cyp26a1

DIOPT Version :10

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_031837.2
• Gene: Cyp26a1 / 13082
• MGIID: 1096359
• Length: 497
• Species: Mus musculus
• Alignment Length: 513
• Identity: 111/513 - (21%)
• Similarity: 210/513 - (40%)
• Gaps: 151/513 - (29%)

  Fly    30 GFPFEKHSGIPFG-CLDSVWRQEKSMGLAIYDVYVKSKERVLGI----YLLFRPAVLIRDADLAR 89
            ||||       || .|..|.::.|         :::.|.|..|.    :|..||.|.:..||..|
Mouse    50 GFPF-------FGETLQMVLQRRK---------FLQMKRRKYGFIYKTHLFGRPTVRVMGADNVR 98

  Fly    90 RVLAQDFASFHDRGVYVDEERDPLSANIFSLRGQSW-RSMRHMLSPCFTSGKLKSMFSTSEDIGD 153
            |:|             :.|.|         |....| .|:|.:|.    :|.|.::..:|
Mouse    99 RIL-------------LGEHR---------LVSVHWPASVRTILG----AGCLSNLHDSS----- 132

  Fly   154 KMVAHLQKELPEEGFKEVDIKKVMQNYA-------IDIIASTIFGLDVNSFENPDNKFRKLVSLA 211
                |.|::           |.:||.::       :.:||           |...:...:.:|..
Mouse   133 ----HKQRK-----------KVIMQAFSREALQCYVPVIA-----------EEVSSCLEQWLSCG 171

  Fly   212 RANNRFNAMFGMMIFLVPSIAQFLFRIGFK-------NPVGLAMLQIVKETVEYREKHGIVRKDL 269
            ..        |::::  |.:.:.:|||..:       .|.|..  :..::.||..|:   :.::|
Mouse   172 ER--------GLLVY--PEVKRLMFRIAMRILLGCEPGPAGGG--EDEQQLVEAFEE---MTRNL 221

  Fly   270 LQLLIQLRNTG-------------KIDEN-DEKSFSIQKT-PDGHIK---------------TIS 304
            ..|.|.:..:|             :|:|| ..|...:|.| |||..|               .:.
Mouse   222 FSLPIDVPFSGLYRGVKARNLIHARIEENIRAKIRRLQATEPDGGCKDALQLLIEHSWERGERLD 286

  Fly   305 LEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDE--TLAKN--DGKITYDSLN 365
            ::|:...:......|.|||.|.|...|..|..||.:|:::::|:..  .|.|:  |.|:..::|.
Mouse   287 MQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREEIKSKGLLCKSNQDNKLDMETLE 351

  Fly   366 KMEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEYFPDPETY 430
            ::::....::||:|..|.:|...|...:.:.:  ..:.||||..|:.|:...|..|:.|.:.|.:
Mouse   352 QLKYTGCVIKETLRLNPPVPGGFRVALKTFEL--NGYQIPKGWNVIYSICDTHDVADIFTNKEEF 414

  Fly   431 DPERF----SEESRNYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMS 484
            :|:||    .|::..:   :|:|||.|.|.|:.:...:|..|:..:::.::.:.::::
Mouse   415 NPDRFIVPHPEDASRF---SFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLN 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	CYP6-like	66..504	CDD:410679	102/476 (21%)
Cyp26a1	NP_031837.2	CYP26A1	55..490	CDD:410731	106/501 (21%)