Protein Alignment Cyp6d4 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_598730.1
• Gene: Cyp4v3 / 102294
• MGIID: 2142763
• Length: 525
• Species: Mus musculus
• Alignment Length: 546
• Identity: 138/546 - (25%)
• Similarity: 236/546 - (43%)
• Gaps: 90/546 - (16%)

  Fly     6 LLAVTLLTLAWFYLKRHYEYWER-RGFPFEKHSGIPFGCLDSVWRQEKSMGLAIYD--------- 60
            |...|:|...:..|..:...|:: |..|             ||.|....:|.|:|.
Mouse    24 LAGATILISIFPMLVSYARKWQQMRSIP-------------SVARAYPLVGHALYMKPNNAEFFQ 75

  Fly    61 --VYVKSKERVLGIYLLF---RPAVLIRDADLARRVLAQDFASFHDRGVYVDEERDPLSANIFSL 120
              :|...:.|.|.|..|:   .|.|.:..|:....:|..  :...|:.......:..|...:.:.
Mouse    76 QLIYYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILTS--SKQIDKSFLYKFLQPWLGLGLLTS 138

  Fly   121 RGQSWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEVDIKKVMQNYAIDII 185
            .|..||:.|.||:|.|....|::......:..:.:|..|:|.:.:|.|   :....:...|:|||
Mouse   139 TGSKWRTRRKMLTPTFHFTILENFLDVMNEQANILVNKLEKHVNQEAF---NCFFYITLCALDII 200

  Fly   186 ASTIFGLDVNSFENPDNKFRKLVSLARANNRFNAMF---GMMIFLVPSIAQFLFRIGFKNPVGLA 247
            ..|..|.::.:..|.|:::      .|...|.:.|.   ..|.:|...:...:|:.|..:..||.
Mouse   201 CETAMGKNIGAQSNNDSEY------VRTVYRMSDMIYRRMKMPWLWFDLWYLVFKEGRDHKRGLK 259

  Fly   248 ML-----QIVKETVEYREK--------HGIV-----RKDLLQLLIQLRNTGKIDENDEKSFSIQK 294
            .|     .::.|.|:.|:.        .|.:     ||..|.||:.:        .||:.
Mouse   260 CLHTFTNNVIAERVKERKAEEDWTGAGRGPIPSKNKRKAFLDLLLSV--------TDEEG----- 311

  Fly   295 TPDGHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKI 359
                  ..:|.|.|..:...|...|.:||.:...:::|.|...||:.:::..|:||...::...:
Mouse   312 ------NRLSQEDIREEVDTFMFEGHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFGRSHRPV 370

  Fly   360 TYDSLNKMEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEYF 424
            |.:.|.|:::||..::||:|.:|.:|:..|..::|..|  ..:.:.|||..:|..|.:|.|..||
Mouse   371 TLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEV--GGYKVTKGTEAIIIPYALHRDPRYF 433

  Fly   425 PDPETYDPER-FSEESRNYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSEI 488
            ||||.:.||| |.|.|:..:|.|::||..|||.||.|:...:..|..:..||:.|.||    |..
Mouse   434 PDPEEFRPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILRQFWVE----SNQ 494

  Fly   489 EFENSGIA----LIPKHGVRVRLSKR 510
            :.|..|:|    |.|.:|:.::|.:|
Mouse   495 KREELGLAGDLILRPNNGIWIKLKRR 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	CYP6-like	66..504	CDD:410679	122/466 (26%)
Cyp4v3	NP_598730.1	CYP4V	76..515	CDD:410773	123/474 (26%)