Protein Alignment Cyp6d4 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: XP_002933245.2
• Gene: cyp46a1.4 / 100498621
• XenbaseID: XB-GENE-29072485
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 548
• Identity: 131/548 - (23%)
• Similarity: 239/548 - (43%)
• Gaps: 100/548 - (18%)

  Fly     2 FSLILLAVTLLTLAW-FYLK-RHYEYWERRGFPFEKHSGIPFGCLDSVWRQEKSMGLAIYDVYVK 64
            |.||::...:..||: .|:| .|.:|.:..|.|   ......|.:.::.:.|::..: ::|:::.
 Frog    17 FLLIIIGAVVAFLAYCAYIKYMHLKYDDIPGPP---RDSFLLGHIPTLSKAEENYSV-VHDLFLH 77

  Fly    65 SKE---RVLGIYLLFRPAVLIRDADLARRVLAQDFASFHDRGVYVDEERDPLSAN-IFSLRGQ-- 123
            ..|   .|..|.:|.|..:.....:..:..|...           ...:||.:.| :|:|.|:
 Frog    78 WAEIYGPVFKINILHRVMIYSTSPESVKECLMSS-----------KYPKDPYTYNQLFNLFGKRF 131

  Fly   124 ------------SWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEVDIKKV 176
                        .|...|.::.|.|::..||.|.....:..::|:..|:::  .:|.:||.:..:
 Frog   132 LGKGLLTDPDHDHWYHQRRIMDPAFSNTYLKEMIGIFNERAEQMMEKLEEK--ADGHQEVSMHSI 194

  Fly   177 MQNYAIDIIASTIFGLDVNSFENPDNKFRKLVSLARANNRFNAMFGMMIFLVPSIAQFLFRIGFK 241
            :....:|:|....||:|:...|.....|...:|        ..:.|||.::             :
 Frog   195 INRVTLDVITKVAFGMDLGLVEGNKTDFPNAIS--------KVLTGMMRYM-------------Q 238

  Fly   242 NPVGLAMLQIVKETVEYREKHGIVRKDLLQLLIQLRNTGK--IDENDEKSFSIQKTPDGHIKTI- 303
            ||.           ::|..||....:::.:....||.|||  |.:..:...:.::.|...:..|
 Frog   239 NPY-----------MQYFPKHWAFVREVQESADLLRKTGKECISQRKKAMQNGEELPKDILTKIL 292

  Fly   304 ---SLE-----AITAQAFI-FYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLA-KNDGK 358
               .||     .|....|| |:|||||||.:..:||:.||.:.||::.:|:.||||.:. |.|
 Frog   293 QCAELENALDDEIMLDNFITFFIAGQETTANQLSFTVMELTRQPEIMTKLRMEVDEVIGFKRD-- 355

  Fly   359 ITYDSLNKMEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEY 423
            |:||.:..:.::...::|::|.||..|..:|...:|.......  ||.|..:..:.|.:....::
 Frog   356 ISYDDIQNLNYMTQVLKESLRFYPPGPGTSRYLKEDTIFEGIK--IPGGVSITFNTYVMGRMEKF 418

  Fly   424 FPDPETYDPERFSEESRNYNPTA------FMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEV 482
            |.||..:|||||       :|.|      :.||..|||.|:.|...::.:|:.:.|::|.|..|:
 Frog   419 FQDPCKFDPERF-------HPAAVKPYFCYFPFALGPRSCLGQIFSQLEAKVILSKLIQRFEFEL 476

  Fly   483 MSRSEIEFENSGIALIPKHGVRVRLSKR 510
            :.......:::| .|.|:.||...|..|
 Frog   477 VPGQSFGIKDTG-TLRPRDGVVCTLKSR 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	CYP6-like	66..504	CDD:410679	114/474 (24%)
cyp46a1.4	XP_002933245.2	CYP46A1-like	72..498	CDD:410706	116/482 (24%)