Protein Alignment Cyp6d4 and Cyp3a41b

DIOPT Version :10

• Sequence 1: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_001098629.1
• Gene: Cyp3a41b / 100041375
• MGIID: 3714859
• Length: 504
• Species: Mus musculus
• Alignment Length: 535
• Identity: 185/535 - (34%)
• Similarity: 289/535 - (54%)
• Gaps: 79/535 - (14%)

  Fly     5 ILLAVTLLTLAWFYLKRHYEYWERRGFPFEKHSGIPFGCLDSVWRQEKSM---GLAIYDVYVKSK 66
            :|||: :|.|.:.|..|.:..::::|.|..|  .:||  |.:|....|.:   .:..|:.|.|:
Mouse    13 VLLAI-ILVLLYRYGTRTHGLFKKQGIPGPK--PLPF--LGTVLNYYKGLWKFDMECYEKYGKT- 71

  Fly    67 ERVLGIYLLFRPAVLIRDADLARRVLAQD-FASFHDRGVYVDEERDP---LSANIFSLRGQSWRS 127
               .|::....|..:|.|.::.:.||.:: |:.|.:|     .|..|   :|..|...:.:.|:.
Mouse    72 ---WGLFDGQMPLFVITDPEMIKNVLVKECFSVFTNR-----REFGPVGIMSKAISISKDEEWKR 128

  Fly   128 MRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEVDIKKVMQNYAIDIIASTIFGL 192
            .|.:|||.|||||||.||...|..||.:|.:|.:| .|:| |.|.:|.|:..|:||:|.||.||:
Mouse   129 YRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQE-AEKG-KPVTMKDVLGAYSIDVITSTSFGV 191

  Fly   193 DVNSFENPDNKF-RKLVSLARANNRFNAMFGMMIFLVPSIAQFLFRIGFKNPVGLAMLQIV---K 253
            :|:|..||::.| .|...:.|.:     .|..::|.|     .||  .|..|| ..||.|.   |
Mouse   192 NVDSLNNPEDPFVEKAKGILRVD-----FFDPLVFSV-----VLF--PFLTPV-YEMLNICMFPK 243

  Fly   254 ETVEY---------------REKHGIVRKDLLQLLIQLRNTGKIDENDEKSFSIQKTPDGHIKTI 303
            :::|:               ::||   |.|.|||::...|.             .|..|.| |.:
Mouse   244 DSIEFFKKFVNRMKESRLDSKQKH---RVDFLQLMMNAHNN-------------SKDKDSH-KAL 291

  Fly   304 SLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKITYDSLNKME 368
            |...||||:.:|..||.|||.||.:||:|.||.:|::.|:||:|:|||| .|....|||::.:||
Mouse   292 SDMEITAQSIVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETL-PNKAPPTYDTVMEME 355

  Fly   369 FLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHV-IPKGTPVVISLYGIHHDAEYFPDPETYDP 432
            :||:.:.||:|.||....|.|.|.:|.   :.|.| ||||:.|:|..|.:|||.:::|:||.:.|
Mouse   356 YLDMVLNETLRLYPIGNRLERFCKKDV---ELNGVYIPKGSTVMIPSYALHHDPQHWPEPEEFQP 417

  Fly   433 ERFSEESR-NYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSEIEFENSGIA 496
            ||||:|:: :.:|..:||||.|||.||..|...:..|||:.|::|||:.:....::|..:.|...
Mouse   418 ERFSKENKGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSRQG 482

  Fly   497 LI-PKHGVRVRLSKR 510
            |: |:..:.:::..|
Mouse   483 LLQPEKPIVLKVVPR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6d4	NP_651082.1	CYP6-like	66..504	CDD:410679	166/463 (36%)
Cyp3a41b	NP_001098629.1	CYP3A	67..493	CDD:410743	168/470 (36%)