Protein Alignment cd and Duox1

DIOPT Version :10

• Sequence 1: NP_651081.1
• Gene: cd / 42681
• FlyBaseID: FBgn0263986
• Length: 830
• Species: Drosophila melanogaster
• Sequence 2: NP_001092767.1
• Gene: Duox1 / 99439
• MGIID: 2139422
• Length: 1551
• Species: Mus musculus
• Alignment Length: 630
• Identity: 181/630 - (28%)
• Similarity: 276/630 - (43%)
• Gaps: 129/630 - (20%)

  Fly   219 RRSTGVCNNKQHPRTYGASMVPYRRMVSPDYADGIAAPRVSHHGRLPPARQVSLKIHRSSYETDS 283
            :|..|..||....| :|:.....:|:|...||||:..|....:  ||..|.:|.::.|.|....|
Mouse    30 QRFDGWYNNLMEHR-WGSKGSRLQRLVPASYADGVYQPLKEPY--LPNPRHLSNRVMRGSAGQPS 91

  Fly   284 --NFTVMLAVFGQFMDHDITATSLTTSQEGESIDCCVAATREQHPECYPVDIL-----PDDPYY- 340
              |.||:...||..:..|:.:.                    :.|.| |.:.|     ..||.:
Mouse    92 LRNRTVLGVFFGYHVLSDLVSV--------------------ETPGC-PAEFLNIYIPHGDPVFD 135

  Fly   341 --KQYNISCMNFVRSA-PAPTGR--FGPRMQLNQATAFIDASVVYGNLEQRQNQLRSFINGSLR- 399
              |:.|: .:.|.||. ...||:  ..||.|.||.|.::|.|.:||:.....:.||||..|.|.
Mouse   136 PDKRGNV-VLPFQRSRWDRNTGQSPSNPRDQSNQVTGWLDGSAIYGSSHSWSDTLRSFSGGQLAS 199

  Fly   400 ----MFVTDDGRQLLP-ISSNPADGCNRVQMTRLGKYCFESGDDRANENLLLTSMHLLWARHHNY 459
                .|.:|....||. ::.:|:.|    |....|.|.|  |..|.|....|.::.|||.|:||.
Mouse   200 GPDPAFPSDSQSSLLMWMAPDPSTG----QGGPRGVYAF--GAQRGNREPFLQALGLLWFRYHNL 258

  Fly   460 LARQLQEQNPHWEDERLYQEARKILGAQMAHITYNEFLPVLLGKNISEAKGLLPAKHNLNAPDTY 524
            .||:|.:::|||.||.|:|.|||.:.|...:|...|:||..|.:...|..|             |
Mouse   259 CARKLAQEHPHWGDEELFQHARKRVIATYQNIAMYEWLPSFLKQTPPEYPG-------------Y 310

  Fly   525 DPEVDPSIANCFAAAAFRFAHTLLP-GLF--NI--------SRDNSTPEAIELHKMLFNPFSLWA 578
            .|.:||||:..|..|:.:|..|::| |::  |.        |.::|...|:.:..      |.|:
Mouse   311 RPFLDPSISPEFVVASEQFLSTMVPSGVYMRNASCHFQGIPSHNSSVSGALRVCN------SYWS 369

  Fly   579 -EH-------GIDHALMTAANTPVMQVDRFFSLEVTQKLFEGTAEDRVPL--CGLDLVSLNIQRG 633
             ||       .:| ||:....:.:.:.:....:|..|..:.|      ||  ...|.::..:|||
Mouse   370 REHPKLQRAEDVD-ALLLGMASQIAEREDHVVVEDMQDFWPG------PLKFSRTDYLASCLQRG 427

  Fly   634 RDHGIPSYPVFRRHCRLPTVDTWEEMSQAI--DNAT-LDSIRQIYESPQD---VDVYTGALSEPP 692
            ||.|:|||...|....|..:..|::::.|:  .|.| |::...:|.  ||   :::..|.|.|..
Mouse   428 RDLGLPSYTKAREALGLSPISHWQDINPALSRSNGTVLEATAALYN--QDLSRLELLPGGLLESH 490

  Fly   693 LDGAIFGPLLSCMVSDQFLRLKLGDSHWYERKMGPQKFTKAQLAEIYKTSLAAIICRNSDGITRV 757
            .|.   |||.|.:|.|||:||:.||.:|:|.... ..|:|.::|||..|||..|:.    .:|.|
Mouse   491 GDP---GPLFSTIVLDQFVRLRDGDRYWFENTRN-GLFSKEEIAEIRNTSLRDILV----AVTNV 547

  Fly   758 REHVMQRLRDGGNPHVDCQDLEGFHFNFEPWSEKQQPQDLHSAGI 802
            ....:|       |:|         |.:.......||..|.:.|:
Mouse   548 DPSALQ-------PNV---------FFWLAGDPCPQPSQLSAKGL 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cd	NP_651081.1	An_peroxidase	218..762	CDD:460804	173/588 (29%)
Duox1	NP_001092767.1	dual_peroxidase_like	32..591	CDD:188652	180/628 (29%)
		EFh	820..881	CDD:238008
		EFh	857..915	CDD:238008
		PLN02292	1089..>1412	CDD:215165
		NOX_Duox_like_FAD_NADP	1277..1551	CDD:99783