DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cd and Nox4

DIOPT Version :9

Sequence 1:	NP_651081.1	Gene:	cd / 42681	FlyBaseID:	FBgn0263986	Length:	830	Species:	Drosophila melanogaster
Sequence 2:	XP_008757865.1	Gene:	Nox4 / 85431	RGDID:	620600	Length:	623	Species:	Rattus norvegicus

Alignment Length:	361	Identity:	64/361 - (17%)
Similarity:	118/361 - (32%)	Gaps:	99/361 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 RHYRSLSTNPEARKLARRGYVENQATIDIAKRFNYTKQPGRSNIGWGPKIVLPDPTVLRLECDFN 215
            |.||.:.:|.....::...:..:...:.:.|. |:..:||:       .|:|..|:|..||   |
  Rat   298 RLYRCIRSNKPVTIISVINHPSDVMELRMIKE-NFKARPGQ-------YIILHCPSVSALE---N 351

  Fly   216 ARY-----RRSTGVCNNKQHPRTYGASMVPYRRMVSPDYADGIAAPRVSHHGRLPPARQVSLKIH 275
            ..:     ..|..||..:.  :.:..::..:..::..|.|....|.::.|...|.|.
  Rat   352 HPFTLTMIMSSVWVCQKRW--QLWPGTVYIHTSILCGDAARHDYASKIHHALLLCPT-------- 406

  Fly   276 RSSYETDSNFTVMLAVFGQFMDHDITATSLTTSQEGE---------------------------- 312
                ||.:.|.|...|.|.:.:.........:||:.|
  Rat   407 ----ETKATFGVHFKVVGDWTERFRDLLLPPSSQDSEILPFIQSRNYPKLYIDGPFGSPFEESLN 467

  Fly   313 -SIDCCVAATREQHPECYPVDILPDDPYYKQYNISCMNFVRSAPAPTGRFGPRMQLNQATAFIDA 376
             .:..|||......|....::.|.||  :|.|.:..:.|:...          ..:.....|.|.
  Rat   468 YEVSLCVAGGIGVTPFASILNTLLDD--WKPYKLRRLYFIWVC----------RDIQSFQWFADL 520

  Fly   377 SVVYGNLEQRQNQLRSFINGSLRMFVTDD------------------GRQLLPISSNPADGCNRV 423
            ..|..|...::|: ..|:|..|.:..||.                  ||....:..:....|||.
  Rat   521 LYVLHNKFWQENR-PDFVNIQLYLSQTDGIQKIIGEKYHTLNSRLFIGRPRWKLLFDEIAKCNRG 584

  Fly   424 QMTRLGKYCFESGDDRANENLLLTSMHLLWARHHNY 459
            :  .:|.:|       ...:.:..::|.|..|:::|
  Rat   585 K--TVGVFC-------CGPSSISKTLHNLSNRNNSY 611

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cd	NP_651081.1	An_peroxidase	218..755	CDD:281139	49/294 (17%)
cd	NP_651081.1	peroxinectin_like	364..750	CDD:188655	21/114 (18%)
Nox4	XP_008757865.1	Ferric_reduct	69..204	CDD:280043
Nox4	XP_008757865.1	NOX_Duox_like_FAD_NADP	311..622	CDD:99783	60/348 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910