DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cd and igsf9ba

DIOPT Version :9

Sequence 1:	NP_651081.1	Gene:	cd / 42681	FlyBaseID:	FBgn0263986	Length:	830	Species:	Drosophila melanogaster
Sequence 2:	XP_009289969.2	Gene:	igsf9ba / 567389	ZFINID:	ZDB-GENE-060503-729	Length:	1475	Species:	Danio rerio

Alignment Length:	689	Identity:	140/689 - (20%)
Similarity:	220/689 - (31%)	Gaps:	262/689 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 YTKQPGR--SNIGWGP--KIVLPDPTVLRLECDFNAR----YRRSTGVCNNKQHPRTYGASMVPY 241
            ||..|..  ..:|..|  .:||.||..      ||.|    ||:..|
Zfish   395 YTCVPYNVLGTMGQSPPATLVLKDPPY------FNVRPGGEYRQEAG------------------ 435

  Fly   242 RRMVSPDYADG-----------IAAPRVSHHGRLPPARQVSLKIHRSSYETDSNFTVMLAVFGQF 295
            |.:|.|..|.|           :..|..|.|..||..   ||:....|.|
Zfish   436 RELVIPCAASGDPEIPTIQWRKVGKPSRSKHNLLPSG---SLQFVSLSKE--------------- 482

  Fly   296 MDH---DITATSLTTSQEGESIDCCVAATREQHPECYPVDILPDDP--YYKQYNISCMNFVRSAP 355
             ||   :..||::.||        ..|:||     .:.:...|..|  .:...:.|..| |...|
Zfish   483 -DHGEWECVATNVVTS--------ITASTR-----LFVIGTSPHAPTNVHVSASTSSAN-VSWEP 532

  Fly   356 APTGRFGPRMQLNQATAFIDASVVYGNLEQR-----QNQLRSFINGSLRMFVTDDG------RQL 409
            ...|.|....           ||.||.::.:     .:.|...:.|| :|::...|      .|.
Zfish   533 GYDGGFEQTF-----------SVWYGPVKVKNDVGTHDWLSIPVPGS-QMWLVVQGLEPKTAYQF 585

  Fly   410 LPISSNP--ADGCNRVQMTRLGKYCFESGD-------------DRANENLLLTSMHLLW---ARH 456
            ..::.|.  ....:.|.....|.|...:.:             :|..:.:|||     |   |.|
Zfish   586 SVLAQNKLGTGPFSEVVTVTTGGYPISTPEPLVLLTPPRCLTANRTQQGVLLT-----WLPPANH 645

  Fly   457 HNYLARQLQE--QNPHWE--DERLYQEARKILGAQMAHITYNEFLPV-LLGKNISEAKGLLPAKH 516
            .:.:.|.:.|  ....||  |:.:.....:|:...:...::.||..: ::...:||:..::
Zfish   646 TSPIDRYVIEFRLGEKWEVLDDLIPATETEIIARDLIQDSWYEFRALAIMDDLVSESSNVV---- 706

  Fly   517 NLNAPDTYDP-EVD------PSIAN-----CFAAAAFRFAHTLLPGLFNISRDNSTPEAIELHKM 569
            .:::.|.:.| |:.      |.:|.     ||.|||..|               ||..|..::|
Zfish   707 GVSSTDPFPPTEISDEGLAKPVVAGIVATICFLAAAILF---------------STLAACFVNK- 755

  Fly   570 LFNPFSLWAEHGIDHALMTAANTPVMQVDRFFSLEVTQKLFEGTAEDRVPLCGLDLVSLNIQRGR 634
                     :|  ...|....:.|:       |:..|:|    :.|...||..|.
Zfish   756 ---------QH--RRKLKRKRDPPL-------SITHTRK----SIESPPPLTPLP---------- 788

  Fly   635 DHGIPSYPVFRRHCRLPTVDTWEEMSQAIDNATLDSIRQIYESPQ----DVDVYTGALSEPPLDG 695
              ||..|              |||..::       |.|....|||    .:...:.|.|.||...
Zfish   789 --GIEPY--------------WEEPDRS-------SYRPPSTSPQLSSGKISPESIASSRPPSLA 830

  Fly   696 AIFGPLLSCMVSDQFLRLKLGDSHWYERKMGPQKFTKAQL-----------AEIYKTSLAAIICR 749
            ::.|         ..|.:|...|...|:::...|.||..:           ||:  |:...:|.|
Zfish   831 SVGG---------HGLYVKKLPSPRKEKELSLYKKTKRAITSKKYSVSKHEAEV--TTPIELISR 884

  Fly   750 NSDGITRVREHVMQRLRDGGNPH-VDC----QDLEGFHF 783
            ..||     ..||       :|: :|.    :.:|||.|
Zfish   885 GPDG-----RFVM-------DPNDIDSSLKPRRIEGFPF 911

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cd	NP_651081.1	An_peroxidase	218..755	CDD:281139	120/613 (20%)
cd	NP_651081.1	peroxinectin_like	364..750	CDD:188655	83/446 (19%)
igsf9ba	XP_009289969.2	IG	30..115	CDD:214652
		I-set	139..225	CDD:254352
		I-set	229..321	CDD:333254
		Ig	345..415	CDD:325142	5/19 (26%)
		Ig	438..503	CDD:319273	20/91 (22%)
		FN3	511..606	CDD:238020	20/107 (19%)
		FN3	622..706	CDD:238020	17/88 (19%)
		Atrophin-1	<924..1361	CDD:331285
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900