Protein Alignment cd and NOX3

DIOPT Version :10

• Sequence 1: NP_651081.1
• Gene: cd / 42681
• FlyBaseID: FBgn0263986
• Length: 830
• Species: Drosophila melanogaster
• Sequence 2: NP_056533.1
• Gene: NOX3 / 50508
• HGNCID: 7890
• Length: 568
• Species: Homo sapiens
• Alignment Length: 552
• Identity: 100/552 - (18%)
• Similarity: 161/552 - (29%)
• Gaps: 218/552 - (39%)

  Fly   344 NISCM-----------NFVRSAPAPTGRFGP-RMQLNQATAFIDASVVYG--------------N 382
            |.:||           :|:|.......  || |.||::...| ...|.||              |
Human    62 NFNCMLILIPVSRNLISFIRGTSICCR--GPWRRQLDKNLRF-HKLVAYGIAVNATIHIVAHFFN 123

  Fly   383 LEQ----RQNQLRSFINGSLRMFVTDDGRQLLPISSNPADGCNRVQMTRLGKYCFESG------- 436
            ||:    :..:.:..:....::..|.:...|.|:.:.|.:....:..|..|    .:|
Human   124 LERYHWSQSEEAQGLLAALSKLGNTPNESYLNPVRTFPTNTTTELLRTIAG----VTGLVISLAL 184

  Fly   437 ---DDRANENLLLTSMHLLWARHHNYL-----------ARQLQEQNPHWEDERLYQEARKILGAQ 487
               ...:.|.:...|..|.|..||.::           .|.::.|.         |::..:....
Human   185 VLIMTSSTEFIRQASYELFWYTHHVFIVFFLSLAIHGTGRIVRGQT---------QDSLSLHNIT 240

  Fly   488 MAHITYNEF-------LPVLLGKNISEAKGLLPAKHNLNAPDTYDPEVDPSIANCFAAAAF-RFA 544
            .....|.|:       :|...||..|..|.:|            .|.|   :..|.....| ||.
Human   241 FCRDRYAEWQTVAQCPVPQFSGKEPSAWKWIL------------GPVV---LYACERIIRFWRFQ 290

  Fly   545 HTLLPGLFNISRDNSTPEAI-ELH------KML----------------FNPFSLWAEHGIDHAL 586
            ..::     |::..|.|..: |||      ||.                ::||:|
Human   291 QEVV-----ITKVVSHPSGVLELHMKKRGFKMAPGQYILVQCPAISSLEWHPFTL---------- 340

  Fly   587 MTAANTPVMQVDRFFSLEV------TQKLFEGTAEDRVPLCGLDLVSLNIQRGRDHGIPSYPVFR 645
                 |...|.| |||:.:      |..|.|....:...|
Human   341 -----TSAPQED-FFSVHIRAAGDWTAALLEAFGAEGQAL------------------------- 374

  Fly   646 RHCRLPTVDTWEEMSQAIDNATLDSIRQIYESPQDVDVYTGALSEPPLDGAIFGPLLSCMVSDQF 710
                   .:.|.....|:|.....::..::..|..|.|..|....|      |..||.
Human   375 -------QEPWSLPRLAVDGPFGTALTDVFHYPVCVCVAAGIGVTP------FAALLK------- 419

  Fly   711 LRLKLGDSHWYERKMGPQKFTKAQ----LAEIYKTSLAAIICRNSDGITRVREHVMQ---RLRDG 768
                   |.||       |.::||    |:::|    ...|||::.......:.::.   |:.:.
Human   420 -------SIWY-------KCSEAQTPLKLSKVY----FYWICRDARAFEWFADLLLSLETRMSEQ 466

  Fly   769 GNPHVDCQDLEGFHFNFEPWSEKQQPQDLHSA 800
            |..|     ...:|.....|.|.|.   ||.|
Human   467 GKTH-----FLSYHIFLTGWDENQA---LHIA 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cd	NP_651081.1	An_peroxidase	218..762	CDD:460804	90/509 (18%)
NOX3	NP_056533.1	PLN02844	<67..>426	CDD:215453	80/469 (17%)
		NOX_Duox_like_FAD_NADP	295..568	CDD:99783	53/283 (19%)