DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cd and mpx

DIOPT Version :9

Sequence 1:	NP_651081.1	Gene:	cd / 42681	FlyBaseID:	FBgn0263986	Length:	830	Species:	Drosophila melanogaster
Sequence 2:	NP_001338766.1	Gene:	mpx / 337514	ZFINID:	ZDB-GENE-030131-9460	Length:	893	Species:	Danio rerio

Alignment Length:	799	Identity:	251/799 - (31%)
Similarity:	378/799 - (47%)	Gaps:	139/799 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 TFIAIVFTALCLALVFSDSLGGADGGPSFFFVVN---------------GSDSELAPNRPLPDEP 103
            ||:.:|  ..|.||    |:|..:..|...|:::               ..|..||..|....:|
Zfish     5 TFLFVV--GCCCAL----SMGAEEESPGRPFILDSIEEAKKIVDAAYKYSRDESLARVRKDVIKP 63

  Fly   104 AAEW-ALQQAALGHHDGAQAVSAGIKALGDREILEEG--LQPNEVNTPSFRHYRSLSTNPEARKL 165
            :.:. .|:|.|....:..:|.....:.|  |.|.|:.  :....:|.      .:|.|..|.:.:
Zfish    64 SDKLRLLKQPARKTREAVRAADYMAQTL--RLISEKAHHVHKRSINA------TNLLTQDELQTI 120

  Fly   166 ARRGYVENQATIDIAKRFNYTKQPG-RSNIGWGPKIVLPDPTVLRLECDFNARYRRSTGVCNNKQ 229
            .|....|.|           |:.|. |:.           |.:        .:||.::|||||::
Zfish   121 TRMTGCEAQ-----------TRPPSCRTT-----------PLI--------NKYRTASGVCNNRK 155

  Fly   230 HPRTYGASMVPYRRMVSPDYADGIAAP------RVSHHGRLPPARQVSLKIHRSS---YETDSNF 285
            :| ..|||..|:.|.:...|.|.::.|      ::.:...||..|.||.:|..::   .|:|.:|
Zfish   156 NP-LLGASNTPFARWLPAQYEDAVSQPKGWDPNKLYNGAALPMVRLVSNRILATADADIESDHDF 219

  Fly   286 TVMLAVFGQFMDHDITATSLTTSQEGES--IDC---CVAATREQHPECYPVDILPDDPYYKQYNI 345
            |.||.:|||::|||:|.|..:.|....|  |||   |     |:...|:|:...|.|...:..
Zfish   220 TFMLTIFGQWVDHDLTFTPFSPSIRSFSNGIDCENSC-----ERSEPCFPISAPPGDQRLRPN-- 277

  Fly   346 SCMNFVRSAP-APTGR----FGP----RMQLNQATAFIDASVVYGNLEQRQNQLRSFIN--GSLR 399
            :|:...|||| ..:|.    ||.    |.|:|..||::||..|||:.:....:||...|  |.||
Zfish   278 TCLPVFRSAPTCGSGHTAYMFGEVPNVREQINTLTAYLDAGQVYGSEDGLAKELRDLTNDGGLLR 342

  Fly   400 M--FVTDDGRQLLPISSNPADGC-------NRVQMTRLGKYCFESGDDRANENLLLTSMHLLWAR 455
            :  ...|:||:|||.:|...:.|       |...:|.:.  ||.:||.|.|||..|.|:|.|:.|
Zfish   343 VNNRFKDNGRELLPFTSVNTNLCATRQKILNDSTLTEVP--CFIAGDARVNENPALNSLHTLFVR 405

  Fly   456 HHNYLARQLQEQNPHWEDERLYQEARKILGAQMAHITYNEFLPVLLGKNISEAKGLLPAKHN--L 518
            .||.|||.|...||.|..|.||||||||:||....:...|:||:::|          |..:|  |
Zfish   406 EHNRLARALHVLNPTWSSETLYQEARKIVGAFNQILVIKEYLPLIVG----------PDAYNRHL 460

  Fly   519 NAPDTYDPEVDPSIANCFAAAAFRFAH-TLLPGLFNISRD-NSTPE--AIELHKMLFNPFSLWAE 579
            .....|:..|||:|||.||.||||||| |:.|.:|.:..: .:.|:  ::.|::..|:|:.:..|
Zfish   461 GPYPGYNENVDPTIANVFATAAFRFAHLTIQPFIFRLDENYKNHPQFPSVPLYEAFFSPWRVIFE 525

  Fly   580 HGIDHALMTAANTP--VMQVDRFFSLEVTQKLFEGTAEDRVPLCGLDLVSLNIQRGRDHGIPSYP 642
            .|||..|......|  :...|......:.::||..|:.     ..|||.|||:||||||.||.|.
Zfish   526 GGIDPVLRGLIGRPAKLNTQDHMLVNALRERLFAFTSH-----IALDLASLNMQRGRDHAIPGYN 585

  Fly   643 VFRRHCRLPTVDTWEEMSQAIDNATL-DSIRQIYESPQDVDVYTGALSEPPLDGAIFGPLLSCMV 706
            .:||.|.|......:|::..::|..| ..:.::|.:|:::||:.|.::||...|...|.|.:|::
Zfish   586 AWRRFCGLSAPQNEQELAVVMNNTELARKLIELYGTPENIDVWLGGVAEPFAPGGRVGSLFACLI 650

  Fly   707 SDQFLRLKLGDSHWYERKMGPQKFTKAQLAEIYKTSLAAIICRNSDGITRVREHVMQRLRDGGNP 771
            |.||.:::.||..|:|..   ..||..|...:...|||.|||.|: ||.:|..... |.|...|
Zfish   651 SRQFQKIRDGDRLWFESN---GVFTTKQKTALASVSLARIICDNT-GILKVPRDPF-RFRSPAN- 709

  Fly   772 HVDCQDLEGFHFNFEPWSE 790
            .|:|.::..  |:.|||.|
Zfish   710 FVNCGNIPA--FDLEPWKE 726

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cd	NP_651081.1	An_peroxidase	218..755	CDD:281139	205/579 (35%)
cd	NP_651081.1	peroxinectin_like	364..750	CDD:188655	148/405 (37%)
mpx	NP_001338766.1	An_peroxidase_like	160..726	CDD:326323	208/597 (35%)
mpx	NP_001338766.1	C1q	772..890	CDD:306816
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	297	1.000	Inparanoid score	I2707
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.870