DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cd and Pxd

DIOPT Version :9

Sequence 1:	NP_651081.1	Gene:	cd / 42681	FlyBaseID:	FBgn0263986	Length:	830	Species:	Drosophila melanogaster
Sequence 2:	NP_001163633.1	Gene:	Pxd / 2768671	FlyBaseID:	FBgn0004577	Length:	690	Species:	Drosophila melanogaster

Alignment Length:	711	Identity:	219/711 - (30%)
Similarity:	318/711 - (44%)	Gaps:	100/711 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 AALGHHDGAQAVSAGIKALGDREILEEGLQPNEVNTPSFRHYRSLSTNPEARKLARRGYVENQAT 176
            |.||....|    .|:|......|:..  ||..    ||.:|...|            |::..|.
  Fly    11 ALLGFISSA----LGLKVSSGYHIVHN--QPQS----SFPNYHGFS------------YLQGSAP 53

  Fly   177 IDIAKR----------FNYTKQPGRSNIGWGPKIVLPDPTVLRLECDF------NARYRRSTGVC 225
            ..|...          |:....|..|..|:.      .||..|:.|..      ...||...|.|
  Fly    54 YVIGNSLPTSPAPQNPFSSPASPPVSAYGYS------FPTAGRVSCAAPPAVCEKTAYRTLDGSC 112

  Fly   226 NNKQHPRTYGASMVPYRRMVSPDYADGIAAPRVSHHG-RLPPARQVSLKIHRSSYETDSNFTVML 289
            |:.:.| ..|.:...|.|:::|.|||||:||..|..| .||.||.|||.........|..||:..
  Fly   113 NHLEQP-GLGVANSKYGRLLTPKYADGISAPTRSVTGDELPSARLVSLVAFGEQDVPDPEFTLHN 176

  Fly   290 AVFGQFMDHDITATSLTTSQEGESIDCCVAATR-----EQHPECYPVDILPDDPYYKQYNISCMN 349
            ..:||.|.||::..:..|..:.....||....|     ..|..|:.:.:.|.||.|.|....|:|
  Fly   177 MQWGQIMTHDMSMQAGGTQSKKHPTRCCTDDGRLIGLDTAHKTCFAIIVPPHDPAYSQVGTECLN 241

  Fly   350 FVRSAPAPTGR-------FGPRMQLNQATAFIDASVVYGNLEQRQNQLRSFINGSLRMFVTD-DG 406
            |||:.   |.|       .||..||...|:::|.|:||||..|:.:.:|.|..|  ||.|.: :|
  Fly   242 FVRTL---TDRDSNCQYQGGPAEQLTVVTSYLDLSLVYGNSIQQNSDIREFQGG--RMIVEERNG 301

  Fly   407 RQLLPISSNPADGCNRVQMTRLGKYCFESGDDRANENLLLTSMHLLWARHHNYLARQLQEQNPHW 471
            .:.||:|.|....|:.|..:.:   |:.|||.|.|:|..|..:..:..|.||.:|..|...|||:
  Fly   302 AKWLPLSRNVTGDCDAVDASEV---CYRSGDVRVNQNPGLAILQTILLREHNRIADALSALNPHY 363

  Fly   472 EDERLYQEARKILGAQMAHITYNEFLPVLLGKNISEAKGLLPAKHNLNAP-----DTYDPEVDPS 531
            :|..|:||||||..||...|:|.|:||:.||     .:.:|..:....||     :.:||.:|||
  Fly   364 DDRTLFQEARKINIAQYQQISYYEWLPIFLG-----GENMLKNRLIYKAPSGSYINDFDPNIDPS 423

  Fly   532 IANCFAAAAFRFAHTLLPGLFNISRDNSTPEAIELHKML--------FN-PFSLWAEHGIDHALM 587
            :.|..|.||||:.|:.:.|..::        ..||.::|        || |..:......|....
  Fly   424 VLNEHATAAFRYFHSQIEGRLDL--------LSELRQVLGSLTLSDWFNRPGIIEVGDNFDSLTR 480

  Fly   588 TAANTPVMQVDRFFSLEVTQKLFEGTAEDRVPLCGLDLVSLNIQRGRDHGIPSYPVFRRHCRLPT 652
            ..|..|....|..|..::...||    ...:|. |.||.||:|||.||||:.||...|..|.|..
  Fly   481 GHATQPEELTDINFDRQIKHFLF----RRNMPF-GSDLRSLDIQRNRDHGLASYNDMREFCGLRR 540

  Fly   653 VDTWEEMSQAIDNATLDSIRQIYESPQDVDVYTGALSEPPLDGAIFGPLLSCMVSDQFLRLKLGD 717
            ..:||.....|....|:.::.:|.|.:|||:..||..|..:.||:.||...|::::||.|.::||
  Fly   541 AHSWEGYGDLISPPILEKLKSLYPSHEDVDLTVGASLEAHVAGALAGPTFLCILTEQFYRTRVGD 605

  Fly   718 SHWYERKMGPQKFTKAQLAEIYKTSLAAIICRNSDGITRVREHVMQRLRDGGNPHVDCQDL 778
            ..::|.......||..||.|:.|.|:|.::|.|.:.|:.::.... |.....||.:.|.::
  Fly   606 RFFFENGDKLTGFTPDQLEELRKASMARLLCDNGNHISSMQPEAF-RTVSHSNPIIPCSNI 665

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cd	NP_651081.1	An_peroxidase	218..755	CDD:281139	190/564 (34%)
cd	NP_651081.1	peroxinectin_like	364..750	CDD:188655	135/400 (34%)
Pxd	NP_001163633.1	An_peroxidase	105..643	CDD:281139	190/564 (34%)
Pxd	NP_001163633.1	peroxinectin_like	260..638	CDD:188655	135/400 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	107	1.000	Domainoid score	I2172
eggNOG	1	0.900	-	-		E1_KOG2408
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	109	1.000	Inparanoid score	I2076
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11475
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.970