DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cd and NOX1

DIOPT Version :9

Sequence 1:	NP_651081.1	Gene:	cd / 42681	FlyBaseID:	FBgn0263986	Length:	830	Species:	Drosophila melanogaster
Sequence 2:	NP_008983.2	Gene:	NOX1 / 27035	HGNCID:	7889	Length:	564	Species:	Homo sapiens

Alignment Length:	161	Identity:	30/161 - (18%)
Similarity:	55/161 - (34%)	Gaps:	67/161 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   708 DQFLRLKLGDSHWYERKMGPQKFTKAQLAEI---YKTSLAAI-ICRNSDGITR---------VRE 759
            |.||:.:..|.::|.||:.......|:.:.:   :.::|..: :|||.....|         :|:
Human    28 DAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTLILLPVCRNLLSFLRGTCSFCSRTLRK 92

  Fly   760 HVMQRLRDGGNPHVDCQDLEGFH-------------------FNFEPWSEKQQPQDLHSAGISRG 805
            .:...|.              ||                   |||:.:|..:|..|        |
Human    93 QLDHNLT--------------FHKLVAYMICLHTAIHIIAHLFNFDCYSRSRQATD--------G 135

  Fly   806 STSVRVMSKANH------------QAHNVTL 824
            |.: .::|..:|            |:.|.|:
Human   136 SLA-SILSSLSHDEKKGGSWLNPIQSRNTTV 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cd	NP_651081.1	An_peroxidase	218..755	CDD:281139	12/50 (24%)
cd	NP_651081.1	peroxinectin_like	364..750	CDD:188655	10/45 (22%)
NOX1	NP_008983.2	Ferric_reduct	66..213	CDD:307763	22/123 (18%)
		NOX_Duox_like_FAD_NADP	297..564	CDD:99783
		Interaction with NOXO1. /evidence=ECO:0000269\|PubMed:16329988	397..536
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910