DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cd and R08F11.7

DIOPT Version :9

Sequence 1:	NP_651081.1	Gene:	cd / 42681	FlyBaseID:	FBgn0263986	Length:	830	Species:	Drosophila melanogaster
Sequence 2:	NP_504048.1	Gene:	R08F11.7 / 187708	WormBaseID:	WBGene00019970	Length:	773	Species:	Caenorhabditis elegans

Alignment Length:	782	Identity:	227/782 - (29%)
Similarity:	349/782 - (44%)	Gaps:	134/782 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 SFFFVVNGSDSELAPNRPLPDEPA-AEWALQQAALGHHDGAQAVSAG----------IKALGDRE 134
            :.|..:|..||..:      .||: |:.|:..:.:.:.:..|....|          :|..| .:
Worm    33 ALFEALNTVDSSFS------SEPSVADGAIVSSQIANAESKQLQFTGDVLEIATQILVKKYG-VD 90

  Fly   135 ILEEGLQPNEVNT------PSFRHYRSLSTNPEARKLARRGYVEN-------------------- 173
            |||:.   |||.|      .|.|..||:.      ::.:..:|.|
Worm    91 ILEDA---NEVLTELNAGESSARKKRSVD------EVEQESFVANLRQKRQSRGKRQGGGGGGRG 146

  Fly   174 ------------QATIDIAKRFNYTKQ----------PGRSNIG-WGPKIVLPDPTVLRLECDFN 215
                        ....|..|:.|..:|          |.:||.. .||.....||.        :
Worm   147 GGGGGRGGDGGRSGEQDGRKKRNSGEQQGGGGRTEYSPPKSNATCQGPPKSCSDPV--------H 203

  Fly   216 ARYRRSTGVCNNKQHPRTYGASMVPYRRMV-SPDYADGIAAPR-VSHHGR-LPPARQVSLKIHRS 277
            .|.|..||.|||:..| |...|:...||:: :..|.||:.|.| .|..|. ||..|.:|.|:|..
Worm   204 DRIRSITGYCNNRGKP-TQANSVTAIRRLLGTTSYTDGLQAIRNTSVTGSPLPSTRLISNKLHDE 267

  Fly   278 SYETDSNFTVML----AVFGQFMDHDITATSLTTSQEGESIDC--CVAATREQHPECYPVDILPD 336
            .  :..||:..:    ...|||:.|||.....:|:::|.|::|  |.:.|... ..|.|:....|
Worm   268 G--STPNFSPSVNHLHMQIGQFIAHDIIFMPSSTAKDGSSLNCTSCSSPTTIS-TNCAPIPAPAD 329

  Fly   337 DPYY---KQYNISCMNFVRSAPAPTGRFGPRMQLNQATAFIDASVVYGNLEQRQNQLRSFINGSL 398
            |.|:   .:....|:...|:....:| ||.|.|::|.:.::|.|.|||:.:.....:|||.||
Worm   330 DKYFTPVSRTEARCIRLTRALNGQSG-FGVRTQIDQNSHYLDMSAVYGSSDCEARTVRSFQNG-- 391

  Fly   399 RMFVTDDG-RQLLPISSNPADGCNRVQMTRLGKYCFESGDDRANENLL---LTSMHLLWARHHNY 459
             :.:|:.| ..:||..:.....|   |.|. ..|||.:||.|   |.|   |..:|:::.:.||.
Worm   392 -LLLTNTGIGYVLPPQAPNDTNC---QSTN-PYYCFTAGDFR---NCLHPGLLPLHIVFIKEHNR 448

  Fly   460 LARQLQEQNPHWEDERLYQEARKILGAQMAHITYNEFLPVLLGKNISEAKGLLPAKHNLNAPDTY 524
            ||.:::...|.|.||::||..|||:.||...|.|||:||.||.........|.|.|........|
Worm   449 LAVKVKAAQPSWNDEQIYQFVRKIMVAQWQQIVYNEYLPKLLTDKYLTDFNLKPMKPGAGPFQGY 513

  Fly   525 DPEVDPSIANCFAAAAFRFAHTLLPGLFNISRDNSTPEAIELHKMLFNPFSLWAEH-------GI 582
            ...::.:::..||||||||.|:  ....:.:|.::|.:.|..:.:..|.|  :|:.       |.
Worm   514 STSMNAALSGEFAAAAFRFGHS--QSRQDFARQDATNKTIGAYDLGNNIF--YADQVYQKSLGGS 574

  Fly   583 DHALMTAANTPVMQVDRFFSLEVTQKLFEGTAEDRVPLCGLDLVSLNIQRGRDHGIPSYPVFRRH 647
            :..|:....|..|||||:||..:..:|||...::.   .|:||:|:||.||||.|:..|..:|..
Worm   575 ETMLLGLIKTAGMQVDRYFSFPIRNQLFEIRGKNG---SGVDLISVNIMRGRDVGLMPYVKYRTL 636

  Fly   648 CRLPTVDTWEEMSQAIDNATLDSIRQIYESPQDVDVYTGALSEPPLDGAIFGPLLSCMVSDQFLR 712
            ..|..||||.::|.....|.|.:::.:|..|.|:|:|||.:.|.||.|...||..|.::::||..
Worm   637 VGLSPVDTWNDLSSTFTAANLAALKTVYADPADIDLYTGLVMETPLAGGQLGPTASWIIAEQFRA 701

  Fly   713 LKLGDSHWYERKM-GPQKFTKAQLAEIYKTSLAAIICRNSDGITRVREHVMQRLRDGGNPHVDCQ 776
            ||.||..:||..: ....||..|:..|.:..||.|.|.|:..||.:...:.    |..:..|.|.
Worm   702 LKTGDRFYYENGVANTVGFTPTQIDAIRRVKLAKIFCENTAIITSINTDIF----DLNSSQVACS 762

  Fly   777 DL 778
            .:
Worm   763 SI 764

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cd	NP_651081.1	An_peroxidase	218..755	CDD:281139	185/560 (33%)
cd	NP_651081.1	peroxinectin_like	364..750	CDD:188655	136/397 (34%)
R08F11.7	NP_504048.1	An_peroxidase	207..745	CDD:281139	185/559 (33%)
R08F11.7	NP_504048.1	peroxinectin_like	359..740	CDD:188655	136/397 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49305
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11475
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.890